Clinical trials
Cardiovascular Disease Risk Factor clinical trials
Below are recruiting cardiovascular disease risk factor clinical trials, each written for real people, not researchers. We’re tracking 159 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT06825936Recruiting
Asian-Mediterranean diet for women's health
This trial tests whether an Asian-Mediterranean diet helps improve health in women who are overweight or obese. You would follow a special eating plan for six months and learn how it affects your weight, heart, and overall well-being.
Singapore, SingaporeAges 21–50 - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60 - NCT07272499RecruitingPhase 2
New drug combo for untreated high-risk mantle cell lymphoma
This trial tests a combination of three drugs (orelabrutinib, lisaftoclax, and rituximab) for people with mantle cell lymphoma who have not had treatment before and have high-risk features. The goal is to see if this combination works better than standard treatments.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT06931470Recruiting
Remote exercise training study for heart health
This study tests whether a remotely supervised exercise program is feasible and helpful for people who are at risk for heart disease but are not currently active enough. You would do exercises at home while being guided and monitored online.
New York, New YorkAges 45 years+ - NCT04686253Recruiting
Study how a heart opening and its flow link to stroke
This study looks at the detailed flow pattern through a patent foramen ovale (PFO)—a small opening in the heart—and how it may relate to stroke, TIA, or migraine. Doctors use special ultrasound testing with contrast to better understand who is most affected.
Beijing, Beijing MunicipalityAges 16–65 - NCT06347276Recruiting
PFO closure and brain microemboli study
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Beijing, Beijing MunicipalityAges 18–65 - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT06633380Recruiting
Different physical activity strategies for breast cancer survivors
This study tests different ways to add physical activity into your daily routine to help manage side effects from breast cancer treatment. The goal is to see if simple, practical strategies can improve your health and well-being while you are on aromatase inhibitors.
Toronto, OntarioAges Any age - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06454864Recruiting
Exercise and Diet for Breast Cancer Survivors
This study tests whether a 6-month program combining weekly supervised exercise and dietary advice can improve health in breast cancer survivors who have completed initial treatments. It aims to help with weight, heart health, and overall well-being.
Toronto, OntarioAges Any age - NCT06345937Recruiting
Heart health lifestyle program for women with multiple risks
This study tests whether a weekly, 24-week lifestyle program at the University of Toronto can improve heart health in women who have several risk factors like being inactive, having a BMI of 25 or higher, and additional issues like high waist circumference or conditions like high blood pressure or pre-diabetes.
Toronto, OntarioAges 30 years+ - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65 - NCT06210490RecruitingPhase 2
Antibody-drug combo with radiation for HER2+ UTUC after surgery
This trial tests a combination of an antibody-drug conjugate (Disitamab Vedotin) plus radiation therapy after surgery to prevent upper tract urothelial cancer from coming back. It is for patients with HER2-positive tumors and high-risk features who cannot receive cisplatin chemo.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05841784Recruiting
Mindfulness coaching for stress and mood after heart risk
This study tests a structured mindfulness program (MBCT-T) to help people who have elevated stress and/or mild anxiety or depression in the setting of heart disease or heart risk factors. It may help improve emotional well-being and stress levels while you live with these health concerns.
New York, New YorkAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT04485871Recruiting
Omega-3 supplements to lower diabetes risk in at-risk adults
This trial tests whether taking omega-3 fatty acids can reduce risk factors for developing diabetes in people with normal cholesterol but other risk factors. You might be asked to follow study visits and dietary/health restrictions for about 33 weeks.
Montreal, QuebecAges 45–74 - NCT05768464RecruitingPhase 2
Surgery aftercare for non-clear kidney cancer at high risk
This Phase 2 trial studies an after-surgery treatment for people with non-clear types of kidney cancer who are at high risk of coming back. It aims to lower the chance of recurrence by giving extra therapy after your tumor is completely removed.
Nanjing, JiangsuAges 18–75 - NCT05920863RecruitingPhase 2
Lenvatinib, immunotherapy, plus liver artery treatment before surgery
This Phase 2 trial tests whether giving lenvatinib and immunotherapy along with TACE (a liver artery treatment) before surgery can lower the risk of hepatocellular carcinoma coming back after surgery. It targets people with certain higher-risk early-stage liver tumors (CNLC IB/IIA).
Hangzhou, ZhejiangAges 18–75 - NCT07061093Recruiting
Hormonal birth control and 24-hour blood pressure study
This study looks at how different types of hormonal birth control might affect your blood pressure over 24 hours. It could help you and your doctor choose a birth control that is safer for your heart.
Genova, GEAges 18–50 - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Huntsville, AlabamaAges 12 years+
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Common questions
- Are there clinical trials for cardiovascular disease risk factor?
- Yes. Clin2 currently lists 159 recruiting cardiovascular disease risk factor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk factor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk factor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.