Clinical trials
Cardiovascular Risk clinical trials
Below are recruiting cardiovascular risk clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06930885RecruitingPhase 3
Polypill and colchicine for heart and artery risk
This trial tests a combination pill (polypill) and a medicine called colchicine to see if they can lower the risk of future heart attacks, strokes, or other artery problems. It is for people who already have a history of heart or blood vessel disease.
Maceió, AlabamaAges 45 years+ - NCT06908473Enrolling by invitationPhase 3
Tongmai Jiangtang capsule for heart risks in metabolic syndrome
This trial tests whether the Tongmai Jiangtang capsule can reduce serious heart and stroke problems in older adults with metabolic syndrome who are also at high risk for heart disease. It focuses on people with a specific traditional Chinese medicine pattern called Qi-deficiency and Blood Stasis.
Guangzhou, GuangdongAges 65 years+ - NCT04544527Recruiting
Study risks for heart disease in older people with diabetes
This study follows older adults with diabetes to understand what factors may raise the risk of heart disease. It may help doctors spot risks earlier in people like you.
Suzhou, JiangsuAges 65–100 - NCT07349498Recruiting
Heart health after stem cell transplant
This study follows patients who have had a stem cell transplant to see how their heart and blood vessels are doing over time. It helps doctors learn about long-term heart risks after transplant.
Beijing, Beijing MunicipalityAges Any age - NCT07438327Recruiting
AI study to improve heart and aorta CT analysis
This trial uses artificial intelligence to better analyze CT scans of the aorta, the large artery that carries blood from your heart. If your CT scan shows the aorta is partly cut off or missing in the images, the AI will help measure the parts that are fully visible.
Chapel Hill, North CarolinaAges 22 years+ - NCT07149714Recruiting
Heart pump support for high-risk angioplasty
This trial tests the iVAC 2L device, a temporary heart pump placed in the main artery, to help patients who need a high-risk angioplasty (PCI) because of a very narrowed or blocked coronary artery. The goal is to prevent the heart from failing during the procedure.
MoscowAges 18 years+ - NCT07128771Enrolling by invitation
Heart effects of gender-affirming hormone therapy
This study looks at how gender-affirming hormone therapy affects the heart and blood vessels. It aims to understand any changes in heart health for transgender individuals starting or continuing this treatment.
Oslo, OsloAges 16 years+ - NCT07087431Recruiting
Genetic risk score for heart disease and health habits
This study looks at whether sharing a genetic risk score for heart disease can help people make heart-healthy changes. If you're not on cholesterol medication, you may be able to join.
Boston, MassachusettsAges 30–75 - NCT00001853Recruiting
Heart disease risk study in Black adults
This study looks at how obesity and blood fat (triglyceride) levels affect heart disease risk differently in Black men and women. You may join if you're a healthy Black adult between 18 and 70, without diabetes.
Bethesda, MarylandAges 18–70 - NCT06542432Enrolling by invitation
Genetic risk test for heart disease prevention
This trial uses a polygenic risk score to see if knowing your genetic risk for coronary artery disease can help prevent a first heart attack. If you have an intermediate 10-year risk and no prior heart events, you may be eligible.
Rochester, MinnesotaAges 40–70 - NCT05888467Recruiting
Exercise study for women at risk of pregnancy heart problems
This study looks at how physical activity affects the heart and blood-vessel health “profile” in women who have risk factors for a pregnancy condition (called GHD, related to preeclampsia risk). It may help researchers find safer or more helpful activity guidance before pregnancy.
Diepenbeek, LimburgAges 18–50 - NCT05951764Recruiting
Checking risk prediction for heart and brain conditions
This study builds or tests computer models that predict risk for heart (cardiovascular) and thinking/memory (neurocognitive) problems using information from people in the general population. It may help improve early detection and planning for care.
ParisAges 45 years+ - NCT07833995Recruiting
Long-term outcomes after heart attack and stenting
This study looks at what happens to people after they have a heart attack and receive a stent (a small mesh tube) to open the blocked heart artery. It will track their health over time to better understand the short- and long-term risks of heart and brain events like another heart attack or stroke, so doctors can improve care.
ShanghaiAges 18 years+ - NCT06443151Recruiting
Blood Vessel Health After Spinal Cord Injury
This study looks at how blood vessel health is affected in people with long-term spinal cord injury (over 1 year). It tests whether blood vessel function plays a role in heart and circulatory risk.
Englewood, ColoradoAges 18–89 - NCT07463898Recruiting
Finding early heart markers in women with preeclampsia
This study looks for proteins in the blood that may show early signs of heart stress in pregnant women with preeclampsia, before symptoms appear. It also uses heart ultrasound to see how the heart changes during pregnancy, which could help find women at risk earlier.
AbujaAges 13–50 - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06114615Recruiting
Remote monitoring after heart treatment to prevent future events
This trial tests whether digital tools can help monitor patients after a stent procedure to lower the chance of another heart problem. It aims to make follow-up care easier and more effective.
Sacramento, CaliforniaAges Any age - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+ - NCT05472207Recruiting
Risk check study for heart disease patients
This study looks at how to better sort people with heart disease into different risk groups. You may be asked for information about your heart condition and related health to help guide future care.
Innsbruck, TyrolAges 18 years+ - NCT06863545Recruiting
PCSK9 Inhibitors for High-Risk Coronary Plaques on CT
This study tests whether adding a PCSK9 inhibitor (a newer cholesterol-lowering shot) to standard treatment can reduce heart risks in people who have certain high-risk plaque features seen on a CT scan of their heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT05693857Recruiting
Understanding heart risk from test results and questionnaires
This study looks at how well questionnaires and cholesterol test results match a person’s future heart risk. It may help researchers improve how doctors spot who is at higher risk and who can benefit from prevention.
ShatinAges 40–90 - NCT06387017Recruiting
Can blood tests improve lung cancer screening in smokers with artery disease?
This study looks at whether certain blood tests can help find lung cancer early in people who have smoked for a long time and also have artery disease. The goal is to see if adding these tests to current screening methods can better identify those at highest risk.
MarseilleAges 45–80 - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Athens, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for cardiovascular risk?
- Yes. Clin2 currently lists 270 recruiting cardiovascular risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.