Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05606562Recruiting
Free dental care during hospital treatment for drug abuse
This study offers free dental treatment to people who are staying in a hospital for drug abuse treatment. It aims to see how adding dental care can help while you’re getting help for substance use.
Narvik, NordlandAges 18 years+ - NCT07866482Recruiting
Nano-silver vs bioactive glass for children's teeth after radiation
This study compares two treatments to protect children's teeth from damage caused by radiation therapy for head and neck cancer. It aims to find which treatment is better at preventing tooth decay and other dental problems.
Cairo, Cairo GovernorateAges 6–10 - NCT07845110Recruiting
Fluoride varnish with laser for early tooth spots in baby teeth
This study tests whether two types of fluoride varnish, with or without a special laser, can help reverse early white spots on baby teeth in children aged 3 to 6. It aims to find the best way to remineralize these spots and prevent cavities.
Alexandria, Alexandria GovernorateAges 3–6 - NCT07829328Enrolling by invitationPhase 4
Can a special rinse help prevent early cavities between teeth?
This trial tests a special rinse called SAP P11-4 to see if it can stop or reverse early cavities between teeth before they need fillings. It may help keep your teeth healthy without more involved dental work.
Schofield Barracks, HawaiiAges 18–74 - NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40 - NCT07748676Recruiting
Comparing two rinsing solutions for deep cavities with tooth pain
This study tests whether rinsing the inside of a painful tooth with a special solution (calcium hypochlorite or sodium hypochlorite) after removing the damaged nerve tissue helps preserve the tooth and reduce pain. It's for people with a deep cavity causing severe toothache, and may help avoid a root canal or tooth loss.
Rohtak, HaryanaAges 18–40 - NCT07730359Recruiting
Testing a treatment for white spots after braces
This trial tests a new gel called Epinamel to reverse white spots that form on teeth after braces are removed. If you recently had braces taken off and have white marks on your teeth, this study might help improve them.
LondonAges 12–60 - NCT06641011Recruiting
Sealing molars with enamel spots: rinsing vs blotting
This study tests whether rinsing off or blotting dry a special silver fluoride liquid before placing a tooth sealant helps the sealant last longer on molars affected by a common condition called molar-incisor hypomineralization. The goal is to find the best way to protect these teeth from cavities.
AnkaraAges 6–14 - NCT07703176Recruiting
Testing a new tooth filling in children's first molars
This study compares how well a newer filling material (Cention-N) works in children's permanent back teeth that have cavities. It's for healthy children ages 8 to 10 who have cavities in both lower or both upper first molars.
Minya, Asyut GovernorateAges 8–10 - NCT06677983Recruiting
How well do Bioflx crowns work for children's back baby teeth?
This study tests how well children and parents like a new type of crown for baby molars. The crowns are placed on back baby teeth that need full coverage, and the study looks at how they perform and how comfortable and satisfied you and your child are.
AlexandriaAges 4–8 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT06517927Recruiting
Long-term dental effects of childhood cancer chemo
This study looks at how chemotherapy given before age 10 affects teeth later in life. Researchers want to know if childhood cancer survivors have more dental problems than others.
BrusselsAges 12–36 - NCT07619729Enrolling by invitationPhase 4
Oral Health Program for People With Type 2 Diabetes
This study tests whether a text-message and online program about caring for your teeth and gums can help people with type 2 diabetes. Researchers want to see if better oral health habits improve overall health outcomes.
Long Island City, New YorkAges 18 years+ - NCT06706115Recruiting
Testing breast milk nasal drops in preterm babies
This study tests whether putting a few drops of breast milk into a preterm baby's nose can help their brain get more oxygen. It is for babies who are not yet ready to feed all by mouth and who don't have certain health problems.
KonyaAges 6 months–9 months - NCT04119180RecruitingPhase 4
Sedation vs protective positioning for kids' dental work
This study compares two ways of keeping children comfortable and safe during dental treatment: sedation or a protective positioning approach. It may help find which method works better for comfort and safety for children who need fillings or other cavity repair.
Goiânia, GoiásAges 1–7 - NCT07547904Recruiting
Bioactive filling material for back tooth cavities
This trial tests a newer type of tooth-filling material (bioactive bulk-fill) in back teeth that need repair. Researchers will compare how well it works compared to standard fillings, which may help improve how long fillings last.
IstanbulAges 18–50 - NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT05981573Recruiting
Measuring methadone doses for chronic pain
This trial is for people with chronic pain who take daily methadone. It aims to measure how much methadone is in your body to help doctors find the right dose.
Lemon Grove, CaliforniaAges 18–70 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT07344038Recruiting
Bioceramic Putty vs MTA and Crowns for Baby Teeth
This study compares two types of putty used to treat the nerve of a deep cavity in a baby tooth, and then looks at two types of crowns (caps) placed on top. It's for healthy children ages 5–7 who need this treatment on a back baby tooth.
AlexandriaAges 5–7 - NCT07343063Recruiting
Comparing tooth-colored fillings for front teeth cavities
This trial tests different tooth-colored materials for fixing cavities on the front teeth (Class III and IV restorations). It aims to find which type lasts longest and works best for patients in good general health.
Merkez, Rize ProvinceAges 18 years+ - NCT07343050Recruiting
Testing flowable composites for tooth fillings and sensitivity
This trial is testing if a special type of dental filling material (flowable composite) causes less tooth sensitivity after getting a cavity filled. It may help people with cavities in the back teeth.
Merkez, Rize ProvinceAges 18 years+ - NCT06699199RecruitingPhase 4
Testing silver diamine fluoride on mouth bacteria in kids
This study tests if a liquid medicine (silver diamine fluoride) painted on baby teeth cavities can change the bacteria in a child's mouth. It is for healthy children ages 4–10 with an open cavity.
Jeddah, Mecca RegionAges 4–12
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 112 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.