Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06677983Recruiting
How well do Bioflx crowns work for children's back baby teeth?
This study tests how well children and parents like a new type of crown for baby molars. The crowns are placed on back baby teeth that need full coverage, and the study looks at how they perform and how comfortable and satisfied you and your child are.
AlexandriaAges 4–8 - NCT06372561Recruiting
Melatonin vs MTA for treating tooth nerve in children
This trial compares two materials—melatonin and MTA (a commonly used dental material)—for treating the nerve of a child's permanent back tooth that has a cavity but isn't infected. The goal is to see which material works better to keep the tooth healthy.
IsmailiaAges 6–8 - NCT05272254RecruitingPhase 2
Povidone iodine in kids’ dental cavities surgery
This trial tests whether povidone iodine helps prevent problems or improves outcomes when children with severe early childhood cavities need dental treatment in the operating room. You may be able to join if your child fits the age and dental needs and has no iodine-related or thyroid problems.
Rochester, New YorkAges 2 years–5.9 years - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT06489093RecruitingEarly Phase 1
Silver agents for early cavities in children's baby teeth
This study checks if silver-containing agents can help heal early white spots (cavities) on baby teeth of children aged 3 to 8. It compares different silver treatments to see which works best for stopping or reversing these early cavities.
PlovdivAges 3–8 - NCT06683833RecruitingPhase 4
Comparing materials for protecting tooth nerves in deep cavities
This study compares three materials used to protect the nerve inside a deep cavity. If you have a deep cavity in a live tooth, you may be able to join and help find which material works best.
CairoAges 22–45 - NCT07146464Recruiting
Peptide vs calcium paste for early cavity spots
This trial tests whether a new peptide treatment or a calcium-phosphate paste works better at reversing early white-spot cavities on front teeth. If you're a young adult with early decay on your front teeth, you may be able to join.
Cairo, Cairo GovernorateAges 15–25 - NCT06495320Recruiting
Teaching parents about safe medicine use for hospitalized children
This study tests whether teaching parents about safe and correct medicine use (rational drug use) changes their attitudes. It's for parents of children up to age 12 who are currently in the hospital and who haven't had this training before.
BilecikAges Any age - NCT06543680Recruiting
Comparing two tooth-filling materials for non-cavity neck lesions
This trial compares two types of tooth fillings for wear-and-tear cavities that form near the gum line on the side of the tooth (non-carious cervical lesions). It tests whether a newer self-sticking resin composite works as well as a glass ionomer filling that is often used for these spots.
Al Mansurah, DakahliyaAges 30–60 - NCT07343063Recruiting
Comparing tooth-colored fillings for front teeth cavities
This trial tests different tooth-colored materials for fixing cavities on the front teeth (Class III and IV restorations). It aims to find which type lasts longest and works best for patients in good general health.
Merkez, Rize ProvinceAges 18 years+ - NCT07111403Recruiting
Testing remineralizing agents for early white spots on teeth
This study tests whether a special remineralizing agent can help reverse early white spots (soft spots) on adult teeth before they become cavities. It's for people who have a few small spots but keep their teeth clean.
Al MansurahAges 14–26 - NCT05816525Recruiting
Study tooth symptoms and cavity depth after partial removal
This study looks at how tooth symptoms and the depth of a cavity affect outcomes when dentists remove only part of the decayed tissue. You might benefit by getting care guided by careful tooth testing and dental imaging, while contributing to better treatment decisions for deep cavities.
EspooAges 18–50 - NCT06918639Recruiting
Pulpotomy for painful adult teeth with deep cavities
This study tests a treatment called pulpotomy for adults with a deep cavity in a tooth that is causing pain. If you have a tooth that hurts but is still healthy enough to save, this treatment might help relieve the pain and keep the tooth.
Alcorcón, MadridAges 18 years+ - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT07730359Recruiting
Testing a treatment for white spots after braces
This trial tests a new gel called Epinamel to reverse white spots that form on teeth after braces are removed. If you recently had braces taken off and have white marks on your teeth, this study might help improve them.
LondonAges 12–60 - NCT07327060Recruiting
Camera-Assisted Parent Training for Children's Teeth
This study tests whether teaching parents with a small intraoral camera can help improve their child's toothbrushing habits. It focuses on children ages 5–7 who have a new permanent molar coming in.
AydinAges 5–7 - NCT07343050Recruiting
Testing flowable composites for tooth fillings and sensitivity
This trial is testing if a special type of dental filling material (flowable composite) causes less tooth sensitivity after getting a cavity filled. It may help people with cavities in the back teeth.
Merkez, Rize ProvinceAges 18 years+ - NCT07344038Recruiting
Bioceramic Putty vs MTA and Crowns for Baby Teeth
This study compares two types of putty used to treat the nerve of a deep cavity in a baby tooth, and then looks at two types of crowns (caps) placed on top. It's for healthy children ages 5–7 who need this treatment on a back baby tooth.
AlexandriaAges 5–7 - NCT07220850Recruiting
Oral health help for caregivers of kids having dental surgery
This trial tests a program to help caregivers improve their child's oral health after dental surgery. It may be a good fit if you care for a child under 8 years old who is getting dental surgery at the University of Illinois at Chicago clinic.
Chicago, IllinoisAges Up to 7 years - NCT07703176Recruiting
Testing a new tooth filling in children's first molars
This study compares how well a newer filling material (Cention-N) works in children's permanent back teeth that have cavities. It's for healthy children ages 8 to 10 who have cavities in both lower or both upper first molars.
Minya, Asyut GovernorateAges 8–10 - NCT03753256Recruiting
Testing a dental eye scan during orthodontic treatment
This study checks whether an optical coherence tomography scan—a quick, non-invasive imaging test—can help in dentistry for people who need orthodontic (braces/alignment) treatment. If you join, you’ll likely be scanned as part of the study and your dentist/doctor will compare results to see how useful the scan is.
HeidelbergAges 6 years+ - NCT04040920Recruiting
Ozone treatment before dental sealants
This trial tests whether applying ozone to certain back teeth before placing sealants helps the sealants work better. You might qualify if you need sealants on specific molars and can safely have the area isolated during treatment.
Trieste, TriesteAges 6–16
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 122 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.