Clinical trials
Chemotherapy Effect clinical trials
Below are recruiting chemotherapy effect clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06041477RecruitingPhase 3
Combining treatments for liver cancer before surgery
This study tests whether giving targeted therapy and immunotherapy at the same time or one after the other is better for shrinking liver tumors that can't be removed right now but might be removable after treatment.
Guangzhou, GuangdongAges 18–75 - NCT06226857RecruitingPhase 3
Anti-EGFR for left-sided, RAS wild-type metastatic colorectal cancer
This trial tests whether anti-EGFR therapy works better for people with left-sided colorectal cancer that has spread, whose tumors do not have certain gene mutations (RAS wild-type). It is for those who have not yet had treatment for metastatic disease.
MoscowAges 18–99 - NCT06313203RecruitingPhase 2
Chemotherapy with or without liver-directed treatment for bile duct cancer
This trial tests whether adding a liver-directed treatment (HAI floxuridine or SIRT) to standard chemotherapy (GemOx) is more effective for people with bile duct cancer inside the liver that cannot be removed by surgery. It may be an option for those whose cancer is only in the liver or nearby lymph nodes.
Oslo, OsloAges 18 years+ - NCT06892158Recruiting
Massage therapy for sleep in teens with cancer
This trial studies if massage therapy can help teenagers and young adults with cancer sleep better while they are in the hospital. Participants will receive massage sessions and answer questions about their sleep.
Washington D.C., District of ColumbiaAges 12–21 - NCT03275194RecruitingPhase 2
HIPEC during interval surgery for advanced ovarian cancer
This trial looks at whether a heated chemotherapy treatment given in the abdomen during a planned second surgery (HIPEC) can improve outcomes for certain advanced ovarian cancers. It is for people who have already had initial chemotherapy and partially responded, with enough health to safely undergo surgery.
Mexico CityAges 18–70 - NCT07391774RecruitingPhase 3
Hormone therapy with or without chemo for early breast cancer
This trial tests whether skipping chemotherapy and using only hormone therapy with a drug called ribociclib works as well as chemotherapy followed by hormone therapy with ribociclib for certain early breast cancers that have a low risk of coming back.
Jonesboro, ArkansasAges 18 years+ - NCT05874297Recruiting
Online nutrition coaching to help breast cancer chemo side effects
This study tests whether an online nutrition education program can reduce or lessen side effects from chemotherapy in people with breast cancer. If you qualify, you would complete online lessons and questionnaires through the rest of your chemotherapy.
Seattle, WashingtonAges 18 years+ - NCT03137095Recruiting
Study how chemotherapy affects brain function in breast cancer
This study looks at changes in thinking and brain function in people with early to locally advanced breast cancer before and during chemotherapy. You may also be offered a brain MRI in a separate optional part of the research to learn more about brain changes.
Rochester, New YorkAges 21 years+ - NCT06725953Recruiting
Remote exercise program for cancer survivors with or without diabetes
This study tests a 12-week home-based physical activity program to see if it helps cancer survivors who had chemotherapy and now have memory or thinking problems. It includes both survivors with type 2 diabetes and those without.
Oklahoma City, OklahomaAges 18 years+ - NCT06468943Enrolling by invitationPhase 2
New drug combo for non-GCB diffuse large B-cell lymphoma
This trial tests a combination of three targeted drugs (polatuzumab vedotin, zanubrutinib, and R-CHP) for people newly diagnosed with a specific subtype of DLBCL called non-GCB. The goal is to see if this powerful mix can work better than standard treatment.
Suzhou, NanjingAges 18 years+ - NCT03589729RecruitingPhase 2
Dexrazoxane to help protect the heart during blood-cancer chemo
This Phase 2 study tests dexrazoxane, a heart-protecting medicine, to reduce heart side effects from chemotherapy in people with certain blood cancers. If you qualify, you would receive dexrazoxane along with chemotherapy, and the team will monitor your heart function closely.
Houston, TexasAges 12 years+ - NCT06669416Recruiting
A study on taste changes during chemotherapy
This study looks at how taste may change when you start chemotherapy for cancer. It aims to help doctors better understand and support patients through these changes.
Chicago, IllinoisAges 18 years+ - NCT07069790Recruiting
Chemotherapy effects on body reflexes after breast cancer treatment
This study looks at how chemotherapy affects the body's automatic reflexes, like heart rate and blood pressure control. It compares women who recently finished chemo for breast cancer with healthy women to understand side effects and recovery.
StrasbourgAges 18 years+ - NCT06946901RecruitingPhase 2
Heated chemo in abdomen plus IV chemo for pancreatic cancer
This trial tests a treatment that combines heating chemotherapy drugs and delivering them directly into the abdomen (HIPEC) with standard chemotherapy through a vein. It is for people whose pancreatic cancer has spread to the lining of the abdomen but not to other organs, and who have not had prior cancer treatment.
Changsha, HunanAges 18–80 - NCT07202819Recruiting
Chemotherapy and MRI before bladder surgery
This study looks at how well MRI scans can detect bladder cancer after chemotherapy, before surgery to remove the bladder. It may help doctors know if the chemo is working.
Asyut, Asyut GovernorateAges 18 years+ - NCT07244016Recruiting
TCR test to guide immunotherapy and chemo for extensive SCLC
This trial tests whether a blood test (TCR) can help predict how well a combination of the immunotherapy drug tislelizumab and chemotherapy works for people with extensive-stage small cell lung cancer (SCLC) that has not been treated before.
Zhengzhou, HenanAges 18 years+ - NCT07675967Recruiting
Blood Cell Changes During Cancer Treatment
This study is for people with solid tumors who are about to start chemotherapy or radiation. It looks at how these treatments affect blood cells and may help doctors understand changes in blood health over time.
Boston, MassachusettsAges 18 years+ - NCT06955702Recruiting
Cryotherapy to Prevent Eyelash Loss from Chemo
This trial tests if cooling the eyelids during chemotherapy can prevent eyelash loss in women with newly diagnosed breast cancer. It is for those who have not yet started treatment.
Santander, CantabriaAges 18 years+ - NCT04901234RecruitingPhase 2
Adaptive radiation for advanced throat cancer
This study tests an approach called “adaptive radiotherapy,” where the radiation plan may be adjusted based on how your tumor and anatomy look during treatment. It is for adults with biopsy-proven oropharyngeal (throat) squamous cell carcinoma who are planning curative radiation, with or without chemotherapy.
MelbourneAges 18 years+ - NCT07524829Recruiting
Phone-based nurse support for breast cancer medication side effects
This study tests whether regular phone check-ins with a nurse can help catch and manage side effects from CDK4/6 inhibitor medications (like palbociclib, ribociclib, or abemaciclib) that you're taking for breast cancer. The goal is to help you stay on treatment safely and feel better.
Asti, ASTIAges 18 years+ - NCT07762586RecruitingPhase 2
Neoadjuvant chemotherapy for muscle-invasive bladder cancer
This study looks at how well a standard chemotherapy given before surgery works for muscle-invasive bladder cancer. It aims to see if higher responses lead to better outcomes.
New Brunswick, New JerseyAges 18–90 - NCT05937477Recruiting
AI tool study to predict chemotherapy side effects and symptoms
This study tests an artificial-intelligence (AI) tool in a phone app that helps predict side effects and symptoms from chemotherapy. It may help patients and their care team plan and respond to side effects more effectively.
Seoul, GangnamguAges 20 years+ - NCT04107077RecruitingPhase 2
HIPEC surgery plus chemotherapy for advanced stomach cancer
This study tests whether a specialized surgery called HIPEC (heat-treated chemotherapy placed in the belly) can improve outcomes for people with advanced stomach cancer that has reached the lining of the abdomen. It’s given after you’ve already had standard chemotherapy, aiming to better control disease in the belly.
Chicago, IllinoisAges 18 years+ - NCT05885048Recruiting
Testing how cancer treatments affect future fertility
This study looks at how treatments that can harm ovaries or testicles (like certain chemotherapy, radiation, and immune therapies) may affect fertility. It may help you and others by measuring hormone levels (and in some cases sperm) before and during/after treatment.
BernAges 14–50
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Common questions
- Are there clinical trials for chemotherapy effect?
- Yes. Clin2 currently lists 135 recruiting chemotherapy effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.