Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,988 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04824027Recruiting
Breast ultrasound testing during chemotherapy for breast cancer
This study looks at how breast tissue changes during chemotherapy given before surgery (neoadjuvant therapy). It may help doctors better understand treatment effects by taking special breast measurements.
New York, New YorkAges 18 years+ - NCT07041710Recruiting
Aromatherapy for taste and smell problems from chemo
This trial tests whether aromatherapy can help improve taste and smell problems caused by chemotherapy. It is for people who are still undergoing chemotherapy and have noticed these side effects.
VilleurbanneAges 18 years+ - NCT07042438RecruitingPhase 2
Fecal transplant to improve CAR T therapy for lymphoma
This study tests whether a fecal transplant (transferring healthy gut bacteria) can improve outcomes for people with certain lymphomas who have taken strong antibiotics and are about to get CAR T-cell therapy (Yescarta). The goal is to see if rebuilding gut bacteria helps the treatment work better.
Duarte, CaliforniaAges 18 years+ - NCT07042685RecruitingPhase 2
5-FU and Fruquintinib for advanced colorectal cancer
This trial tests a combination of two drugs (5-FU and fruquintinib) in people with advanced colorectal cancer that cannot be removed by surgery or has spread. It is for those who have not had chemotherapy before.
Houston, TexasAges 18 years+ - NCT07040189Recruiting
AI nutritional plan for taste changes from chemo
This study tests an AI-created diet plan to help with taste problems caused by chemotherapy. It may help manage taste issues by suggesting recipes tailored to you.
Munich, BavariaAges 18 years+ - NCT04691284Recruiting
Test how the gut microbiome changes during major cancer treatment
This study looks at your gut “microbiome” (the bacteria in your intestines) while you receive high-dose chemotherapy and a stem cell transplant, or CAR-T cell therapy. Researchers hope to understand how these treatments affect the microbiome, which may relate to how well patients do.
Bratislava, SlovakiaAges 18 years+ - NCT07033689RecruitingEarly Phase 1
Testing Suizenji for newly diagnosed pancreatic cancer
This trial tests a new ultrasound treatment called Suizenji for people with pancreatic cancer that cannot be removed by surgery. The goal is to see if it can safely target the tumor.
San Francisco, CaliforniaAges 18 years+ - NCT07024615RecruitingPhase 1
Study of ASP2138 before surgery for pancreatic cancer
This study tests an experimental drug, ASP2138, given before surgery for pancreatic cancer that is still removable. After surgery, you will receive standard chemotherapy. The goal is to see if adding ASP2138 before surgery helps improve outcomes.
Boston, MassachusettsAges 18 years+ - NCT07025889RecruitingPhase 1/Phase 2
IBI343 plus sintilimab and chemo for gastric cancer
This trial tests a new combination of IBI343, sintilimab, and chemotherapy for people with advanced stomach or gastroesophageal junction cancer that hasn't been treated yet. It's for those whose tumors are CLDN18.2-positive and not HER2-positive.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07030140RecruitingPhase 2
Immunotherapy, radiation and chemo for bile duct cancer
This trial tests a new combination of immunotherapy (tislelizumab), radiation, and chemotherapy before surgery for people with bile duct cancer that is hard to remove. The goal is to shrink the tumor enough to allow successful surgery.
Jinan, ShandongAges 18–75 - NCT07033819RecruitingPhase 2
Fuzuloparib and apatinib before surgery for ovarian cancer
This trial tests a combination of two oral drugs—fuzuloparib (a PARP inhibitor) and apatinib (which blocks blood vessel growth to tumors)—given before surgery for advanced ovarian cancer that cannot be removed right away. It is for people whose tumors have a specific genetic marker (HRD positive) and who have not had prior cancer treatment.
Beijing, Beijing MunicipalityAges 18–70 - NCT04084496RecruitingPhase 2
FOLFIRINOX chemo after surgery for pancreatic cancer
This Phase 2 study tests whether FOLFIRINOX given after pancreatic surgery can lower the chance the cancer comes back. It focuses on people with pancreatic ductal adenocarcinoma who had their tumor completely removed and have no spread to distant organs.
Guangzhou, GuangdongAges 18–79 - NCT04861558RecruitingPhase 3
Warm chemotherapy placed in the abdomen to treat colon cancer
This Phase 3 trial tests whether heating chemotherapy and delivering it directly into the abdomen (along with standard surgery for cancer spread) works better for colon cancer that has spread to the lining of the abdomen. It may help control the cancer after surgery, especially when the spread is mainly in the abdomen (and possibly the liver or lungs).
AhmedabadAges 18–79 - NCT07023315RecruitingPhase 3
Study of cadonilimab plus SOX before and after surgery for stomach cancer
This trial tests if adding the drug cadonilimab to standard chemotherapy (SOX) before and after surgery can help treat stomach or gastroesophageal junction cancer that can be removed. The goal is to see if this combination improves outcomes for patients.
Beijing, Beijing MunicipalityAges 18–75 - NCT07020065RecruitingPhase 2
Reduced chemo plus immunotherapy vs immunotherapy alone for older lung cancer patients
This trial tests whether a reduced dose of chemotherapy plus an immunotherapy drug (Cemiplimab) works better than Cemiplimab alone for older or frail patients with advanced lung cancer whose PD-L1 level is below 50%. It aims to find a gentler but effective treatment option.
Fribourg, Villars-sur-GlâneAges 70 years+ - NCT07018622RecruitingPhase 2
Protecting kidneys from platinum chemotherapy damage
This trial tests a way to protect your kidneys while you receive platinum-based chemotherapy (cisplatin or carboplatin) for a solid tumor. It may help reduce the risk of kidney damage so you can complete your treatment more safely.
México, TlalpanAges 18 years+ - NCT04962711Recruiting
Risk-guided plan to prevent heart failure after cancer treatment
This trial tests whether a personalized, risk-based heart care plan can help prevent heart failure in people who had certain cancer treatments. It focuses on monitoring and guiding treatment, using heart ultrasound results and other health factors.
Melbourne, VictoriaAges 40–85 - NCT05188859RecruitingPhase 2
Testing sintilimab, anlotinib, and chemo for pleural mesothelioma
This Phase 2 study tests whether adding three medicines—sintilimab, anlotinib, and standard platinum chemo—can control malignant pleural mesothelioma that cannot be removed by surgery. It may help shrink tumors and slow disease progression, but you must meet specific health and prior-treatment requirements.
Taiyuan, ShanxiAges 18 years+ - NCT07007559RecruitingPhase 2
Evorpacept with trastuzumab and chemo for HER2-positive breast cancer
This study tests an experimental drug called evorpacept when given with trastuzumab and chemotherapy for people with HER2-positive breast cancer that has spread. The goal is to see if this combination can shrink tumors or slow down the cancer.
Phoenix, ArizonaAges 18 years+ - NCT07010419RecruitingPhase 3
Firmonertinib vs placebo for early-stage lung cancer with rare EGFR mutations
This trial tests if Firmonertinib, a targeted pill, can prevent lung cancer from returning after surgery in people with non-small cell lung cancer that has certain uncommon EGFR gene changes. If you have had complete tumor removal and have one of these specific mutations, this study may help you stay cancer-free longer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06944106RecruitingPhase 2
Ivonescimab plus chemo before surgery for pancreatic cancer
This trial tests whether adding the drug ivonescimab to chemotherapy before surgery can help people with borderline resectable pancreatic cancer. The treatment is given for a short time to shrink the tumor and make surgery more likely to succeed.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07003737Recruiting
Blinatumomab before stem cell transplant for high-risk B-ALL
This trial tests giving a drug called blinatumomab before a stem cell transplant for people with high-risk B-cell acute lymphoblastic leukemia (B-ALL) that is in remission and has no detectable cancer cells. The goal is to see if this extra treatment helps prevent the leukemia from coming back after transplant.
Hangzhou, ZhejiangAges 18–65 - NCT07007364RecruitingPhase 2
Testing low-dose radiation with immunotherapy and chemo for early oral cancer
This trial tests if combining a low dose of radiation with an immunotherapy drug (adebrelimab) and a chemotherapy drug (albumin-bound paclitaxel) before surgery can help treat early-stage oral squamous cell carcinoma. It aims to see if this combination is safe and effective.
Wuhan, HubeiAges 18–70 - NCT06998394RecruitingPhase 2
Cadonilimab Plus Chemoradiation for Oligometastatic Cervical Cancer
This trial tests a new immunotherapy drug (cadonilimab) combined with standard chemoradiation for cervical cancer that has spread to a few other places in the body. It aims to see if this combination can help control the cancer better.
Zhengzhou, HenanAges 18 years+
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,988 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.