Clinical trials
Children, Only clinical trials
Below are recruiting children, only clinical trials, each written for real people, not researchers. We’re tracking 2,992 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04903223RecruitingPhase 1
Testing how fat in the liver affects statin use in kids
This early study tests whether “liver fat” changes how a statin (rosuvastatin) works in children and teens. It may help doctors choose safer or more effective dosing in kids based on biology and a specific genetics marker.
Kansas City, MissouriAges 8–21 - NCT04924491RecruitingPhase 1/Phase 2
Treg cell therapy to help prevent rejection after child heart transplant
This early-phase study tests a cell treatment (Treg cells made from a child’s thymus tissue) to help prevent the body from rejecting a new heart. It may help reduce rejection risk, but it is experimental and involves added risks and follow-up.
Madrid, MadridAges Up to 2 years - NCT04881240RecruitingPhase 1
Donor T-cell therapy for CD19-positive leukemia in young patients
This study tests a new treatment using donor immune cells (T-cells) that target a protein called CD19 on leukemia cells. It is for children and young adults with CD19-positive leukemia that has come back or not responded to standard treatments.
Memphis, TennesseeAges Up to 21 years - NCT04923828Recruiting
Study drug resistance in very sick children with infections
This trial enrolls children in the pediatric intensive care unit (PICU) who have a severe infection. It aims to better understand germs and drug resistance so future treatments can be more effective.
Shanghai, Shanghai MunicipalityAges 1 month–16 years - NCT04905381Recruiting
Test a home language program to help toddlers prepare for school
This study looks at whether a home-based language program (called the LENA Start Program) can improve toddlers’ readiness for school. It focuses on families with toddlers around 16–30 months old in the Alief Independent School District area.
Houston, TexasAges 1.3 years–2.5 years - NCT04925375RecruitingPhase 2
Abatacept for children with CVID and lung scarring
This Phase 2 trial tests abatacept to improve a specific type of lung disease in children with common variable immunodeficiency (CVID). It aims to slow or reduce ongoing lung changes seen on CT scans while they continue their usual immune “replacement” therapy.
San Francisco, CaliforniaAges 4 years+ - NCT04897321RecruitingPhase 1
CAR T therapy for children with B7-H3 solid tumors
This early-phase study tests a lab-made immune therapy (CAR T cells) made from your own cells to treat children’s solid tumors that have a specific marker called B7-H3. It is designed for kids whose cancer has come back or did not respond to standard treatment, aiming to shrink tumors and keep the therapy safe.
Memphis, TennesseeAges Up to 21 years - NCT04900597Recruiting
Testing blended tube feeds on kids’ stomach function
This study compares how “blended” tube feeds affect stomach and upper digestive function in children who use a feeding tube. It may help doctors understand whether blended feeds change digestion in ways that matter for comfort and physiology.
Boston, MassachusettsAges 1 year+ - NCT04580368Recruiting
Personalized drug testing for cystic fibrosis using small trials
This trial tests how well cystic fibrosis (CF) medicine works for you using an “n-of-1” approach, meaning you try treatments in a structured, repeated way to see what helps you most. It may help your care team choose the best option for your specific CF genetics and health status.
Cincinnati, OhioAges 6 years+ - NCT03657693Recruiting
MRI test in newborns with breathing problems (BPD)
This study uses MRI (a special scan) to look at babies with bronchopulmonary dysplasia, a long-term breathing condition that can happen after being in the NICU. It aims to learn more about what’s happening in the lungs and how MRI can be used safely in these babies.
Cincinnati, OhioAges Up to 4 months - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT03481881Recruiting
Drug dosing study in children getting routine medicines
This study measures how children’s bodies handle medicines they are already prescribed as standard care. It may help doctors choose safer, more accurate doses for children in the future.
Durham, North CarolinaAges birth–20 years - NCT04103268Recruiting
Study blood tests to understand organ injury in children with sepsis
This study uses special blood testing to learn what is happening in the immune system during sepsis in children and how it may relate to organ injury. Your results may help doctors recognize and treat sepsis earlier and more accurately.
Boston, MassachusettsAges 1 month–17 years - NCT04851119RecruitingPhase 1/Phase 2
Tegavivint for kids and young adults with hard-to-treat solid tumors
This early-phase study tests tegavivint to see how well it works and how safe it is for children and young adults with solid cancers that have come back or are not responding. It may be an option if your tumor type (including certain lymphomas or desmoid tumors) matches the study’s rules.
Birmingham, AlabamaAges 1–30 - NCT04640987RecruitingPhase 1
Stem cell transplant with added T-cells for blood cancers
This Phase 1 study tests a stem cell transplant plan that uses donor T-cells that have been specially processed and then added back. It aims to see if this approach is safer and works better for children and adults with serious blood cancers who need a transplant.
Palo Alto, CaliforniaAges 1 month–45 years - NCT04629469Recruiting
Two types of MRI scans in children
This study compares two MRI scan settings (a lower and higher magnetic field) in children to see how well they work for pediatric patients. It may help doctors choose the best MRI approach for kids without changing any care beyond the scan itself.
Kansas City, MissouriAges birth–22 years - NCT04791748Recruiting
Virtual reality balance training for kids with inner-ear problems
This study uses virtual reality tasks to understand and compare balance and movement in children with long-term inner-ear (vestibular) problems versus those without. It may help doctors learn what supports best balance and safety during daily activities.
ParisAges 7 years+ - NCT04794296Recruiting
Care plan for children newly diagnosed with acute lymphoblastic leukemia
This trial uses a standard treatment plan for children who have just been diagnosed with acute lymphoblastic leukemia (ALL). It aims to guide the best initial treatment for certain cell types of ALL and help improve outcomes while avoiding specific higher-risk subtypes.
AbidjanAges Up to 18 years - NCT04836390Enrolling by invitationPhase 2
Donor immune cell treatment after transplant for high-risk AML
This trial tests an additional immune therapy made from donor natural killer (NK) cells given around the time of a special stem cell transplant for children and young adults with high-risk acute myeloid leukemia (AML). It aims to help prevent the leukemia from coming back or not responding after transplant.
Phoenix, ArizonaAges birth–25 years - NCT04825587Recruiting
Study after first ACL reconstruction in children
This study looks at children’s outcomes after their first ACL ligament surgery using a specific graft (quadriceps tendon). It may help doctors compare and improve how ACL repairs are done in growing kids with open or closing growth plates.
Chicago, IllinoisAges Up to 18 years - NCT04794686Recruiting
Study for children with a brain tumor with multilayer rosettes
This registry research program collects information and tumor samples from people with a specific type of brain embryonal tumor (with multilayer rosettes). It may help researchers understand the tumor better and improve future treatments.
Hackensack, New JerseyAges Any age - NCT04789746Enrolling by invitation
Physical fitness program for children with mobility challenges
This study tests a physical fitness program designed for children who have mobility challenges due to conditions like cerebral palsy. The program aims to improve fitness and overall well-being in a safe and supportive environment.
Chicago Heights, IllinoisAges 6–18 - NCT04786977Recruiting
Measuring a nerve-related eye signal in children on vincristine
This study checks how children’s pupil responses look while they are receiving vincristine (a cancer medicine). The goal is to learn whether a simple eye measurement can reflect how the body is responding to treatment.
Washington D.C., District of ColumbiaAges 6–18 - NCT04840017Enrolling by invitation
Rehab program for balance and walking in flexible flatfeet
This trial tests whether a rehabilitation exercise program can improve balance and walking in children who have flexible flatfeet. The goal is to see if targeted rehab improves posture, stability, and gait (how your child walks).
GdanskAges 7–12
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Common questions
- Are there clinical trials for children, only?
- Yes. Clin2 currently lists 2,992 recruiting children, only studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, only trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, only trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.