Clinical trials · Maryland
Children clinical trials in Maryland
We’re tracking 124 recruiting children studies with a site in Maryland — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT05304585RecruitingPhase 3
Chemo for children with early, low-risk fusion-negative rhabdomyosarcoma
This Phase 3 study tests a chemotherapy plan for children and teens with newly diagnosed, very low-risk or low-risk rhabdomyosarcoma that does not have certain gene fusions (FOXO1 fusion negative). The goal is to see if this treatment can work well while limiting side effects by matching therapy to early-stage risk.
Baltimore, MarylandAges Up to 21 years - NCT05361811Recruiting
Therapy coaching for parents of children with rare genetic syndromes
This trial tests an “Acceptance and Commitment Therapy” program for parents or legal guardians who feel moderate parenting stress. It aims to help caregivers cope in healthier ways and may also improve how they manage stress while supporting their child.
Bethesda, MarylandAges 18 years+ - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Baltimore, MarylandAges 2 years+ - NCT05465174RecruitingPhase 2
Tovorafenib for children and young adults with craniopharyngioma
This trial studies tovorafenib to treat craniopharyngioma in children and young adults. It aims to shrink the tumor or slow its growth, and to learn which patients benefit most and what side effects to expect.
Baltimore, MarylandAges 1–39 - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Bethesda, MarylandAges 18–70 - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Baltimore, MarylandAges 6–39 - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Baltimore, MarylandAges 2–18 - NCT05723198RecruitingPhase 3
Baricitinib for severe childhood hair loss from alopecia areata
This trial tests whether baricitinib can improve severe alopecia areata (patchy, autoimmune hair loss) in children and teens. It’s meant for people who have had long-lasting, severe hair loss and have tried other treatments without enough benefit.
Rockville, MarylandAges 6–17 - NCT05726591Recruiting
Robotic exoskeleton study to improve walking in children
This study looks at how safely using a pediatric robotic exoskeleton over the long term can improve how children walk. It’s for children ages 3–17 who have certain movement or spine-related conditions and who can meet walking and joint-movement requirements.
Bethesda, MarylandAges 3–17 - NCT05829668Recruiting
Behavior plan study for children with Cornelia de Lange syndrome
This study tests a structured behavior assessment and treatment program for children with Cornelia de Lange syndrome who have challenging behaviors. It may help reduce self-injury, aggression, and disruptive behavior through a plan families can carry out.
Baltimore, MarylandAges 3–15 - NCT05919849RecruitingPhase 1
Helping parents support their LGBTQ+ children who face stigma
This Phase 1 study tests a program for parents (or guardians) to help them better support their LGBTQ+ young adult family member who is experiencing stigma and not feeling accepted. It aims to see if the approach can improve support and coping within families.
College Park, MarylandAges 15 years+ - NCT05975671Recruiting
Survey in pediatric ICU to reduce upfront vancomycin use
This study is a survey and quality-improvement effort in participating children’s intensive care units. It aims to understand and change how doctors decide to start vancomycin (an antibiotic) when sepsis is suspected, to improve care and avoid unnecessary use.
Baltimore, MarylandAges Any age - NCT06023589RecruitingPhase 3
Testing tezepelumab for kids with severe asthma
This study tests if tezepelumab can help reduce severe asthma attacks in children ages 5 to 11. It compares the drug to a placebo (a dummy treatment) to see if it is safe and effective.
Baltimore, MarylandAges 5–11 - NCT06066983Recruiting
Treating anxiety in children with autism (DINO RCT)
This study tests a therapy to help young children with autism who also have anxiety. The goal is to reduce anxious behaviors and improve daily life.
Baltimore, MarylandAges 4–6 - NCT06242873Recruiting
Spinal cord stimulation for kids with incomplete injuries
This study tests if mild electrical pulses to the spinal cord can help children ages 3 to 16 with incomplete spinal cord injuries walk better. It is important for children who still have some movement in their legs but need extra help to improve their walking.
Baltimore, MarylandAges 3–16 - NCT06380517RecruitingPhase 3
Headset therapy vs patching for lazy eye in children
This study tests a new way to treat lazy eye (amblyopia) in 4 to 7 year olds using special shows watched through a headset (dichoptic therapy). It compares this to the standard treatment of wearing a patch over the stronger eye. The goal is to see if the headset therapy works as well or better than patching.
Baltimore, MarylandAges 4–7 - NCT06410976Recruiting
Study of hypochondroplasia in children
This study is for children with hypochondroplasia, a condition that causes short stature. It will look at how the condition changes over time and aims to better understand it, with the goal of finding new treatments.
Baltimore, MarylandAges 2.5 years–16 years - NCT06442761RecruitingPhase 1
Collecting stem cells for gene therapy in sickle cell disease
This study tests a new drug called motixafortide to help collect your own blood stem cells for future gene therapy. It is for adults with severe sickle cell disease who are willing to donate their stem cells and meet certain health requirements.
Bethesda, MarylandAges 18 years+ - NCT06498596Recruiting
New ways to study movement in kids with movement disorders
This study tests new ways to measure movement (like walking and joint motion) in children and young adults. It's for people with cerebral palsy and healthy volunteers, to better understand movement differences.
Bethesda, MarylandAges 5–25 - NCT06524882RecruitingPhase 3
Special glasses for lazy eye in children 8 to 12 years old
This trial tests if special movies or games viewed through a headset can improve vision in children with lazy eye (amblyopia). It compares these treatments to wearing glasses alone.
Baltimore, MarylandAges 8–12 - NCT06585631Recruiting
Collaborative care for young men with HIV and substance use
This study looks at how to better support young men living with or at risk for HIV while also addressing substance use. You'll work with a care team that helps you stay healthy and connected to services.
Baltimore, MarylandAges 15–29 - NCT06683092Recruiting
Restarting triple therapy with close monitoring for side effects
This trial tests whether carefully restarting a triple-combination CFTR modulator (VTD) is safe and helpful for people with cystic fibrosis who had to stop or change Trikafta because of mental health side effects or liver injury. You will be closely monitored with surveys and daily diaries to ensure your safety.
Baltimore, MarylandAges 6 years+ - NCT06865664RecruitingPhase 1
Engineered immune cells for relapsed rhabdomyosarcoma in youth
This early-phase trial tests a new immune cell therapy (CAR T cells) for children and young adults whose rhabdomyosarcoma has returned or not responded to standard treatments. The goal is to see if these specially engineered cells can find and attack the cancer.
Bethesda, MarylandAges 3–39
Children trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting children studies listed above.
- National Institutes of Health Clinical Center · 5 studies
- Johns Hopkins University · 4 studies
- Kennedy Krieger Institute · 3 studies
- Greater Baltimore Medical Center · 2 studies
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · 2 studies
- Sinai Hospital of Baltimore · 2 studies
- Wilmer Eye Institute · 2 studies
- DermAssociates PC
What taking part in a children study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Children trials in other states
Common questions
- Are there children clinical trials in Maryland?
- Yes. We're currently tracking 124 recruiting children studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a children study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New children studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.