Clinical trials
Chronic Disease Prevention clinical trials
Below are recruiting chronic disease prevention clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06283966RecruitingPhase 3
Triple inhaler for COPD with heart risk
This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) to see if it can help protect the heart and lungs in people with COPD who also have heart problems or high risk for them.
Athens, AlabamaAges 40–80 - NCT07727915Enrolling by invitation
Using genetics to predict chronic disease risk
This trial uses genetic information to help predict your risk of developing chronic diseases. It aims to create a platform that can identify health risks earlier so you can take preventive steps.
Medellín, AntioquiaAges 18–99 - NCT06224556Recruiting
Preventing frailty in older adults with chronic conditions
This study tests if a personalized prevention program based on a full health check (comprehensive geriatric assessment) can help prevent frailty in older adults who already have at least one long-term health condition (like heart disease, diabetes, or arthritis). If it works, the program could keep you stronger and healthier longer.
BariAges 65 years+ - NCT03890224Recruiting
Testing breathing support needs in COPD with high CO2
This trial studies how different breathing support strategies affect people with COPD who have high carbon dioxide (CO2) in their blood. It may help care teams choose safer respiratory support after a breathing machine is stopped.
Paris, Île-de-France RegionAges 18 years+ - NCT06891677Recruiting
Online therapy and education for COPD
This trial tests a program you can do from home on your computer. It combines talk therapy and education to help you manage your COPD symptoms and feel better.
Norrköping, Östergötland CountyAges 18 years+ - NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Birmingham, AlabamaAges 2–17 - NCT07547098Recruiting
Heart, Kidney, and Metabolism Health Long-Term Study
This research study tracks patients with heart disease, kidney disease, or metabolic conditions (like diabetes) over time to understand how these conditions connect and affect long-term health. By collecting medical records and health information, researchers aim to predict outcomes and improve care.
Fuzhou, FujianAges 18–80 - NCT06493799RecruitingPhase 3
Injectable placenta extract for fatty liver disease
This trial tests an injectable medication made from human placenta to see if it can improve liver health in people with fatty liver disease (from alcohol or other causes). It may help lower liver enzyme levels and reduce liver damage.
Yongin-siAges 19–70 - NCT06253507Enrolling by invitationPhase 1/Phase 2
Gene therapy for p47 chronic granulomatous disease
This trial tests a new gene therapy for people with a specific type of chronic granulomatous disease (p47 CGD). The treatment uses your own blood stem cells, which are modified in a lab to help your body fight infections better. It is for people who do not have a matched stem cell donor and have had serious infections.
Bethesda, MarylandAges 3–65 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT06335992Recruiting
Lung tissue repair study for COPD patients through exercise
This trial tests whether a special exercise program can help repair lung tissue in people with Chronic Obstructive Pulmonary Disease (COPD). It aims to find new ways to improve lung health and quality of life.
LundAges 50–85 - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT05283512Recruiting
IV versus drink fluids to protect kidneys after CT scan
This study compares giving fluids through a vein versus drinking fluids to lower the risk of sudden kidney injury after a CT scan with contrast dye. It focuses on adults with very poor kidney function who are scheduled for an elective CT scan.
Odense C, FynAges 18 years+ - NCT06981585Recruiting
Physical effects in children with chronic kidney failure
This study looks at physical changes in children with chronic kidney failure compared to healthy children. If you join, you will have some physical measurements taken to help doctors understand how kidney disease affects the body.
IzmirAges 8–18 - NCT05325099RecruitingPhase 1/Phase 2
Azacitidine to help prevent kidney injury after heart surgery
This early-phase study tests whether azacitidine (a medication that changes how cells read genes) can lower the risk of acute kidney injury after cardiac surgery, especially in people already at risk along the chronic kidney disease (CKD) pathway. It aims to protect kidney function during the vulnerable period after surgery.
TaipeiAges 20 years+ - NCT07025538RecruitingPhase 1
Preventing chronic graft-versus-host disease with ruxolitinib
This trial tests whether the drug ruxolitinib, given based on a blood test that predicts risk, can prevent chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It may help people who have a higher risk of developing this complication.
Duarte, CaliforniaAges 18 years+ - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Los Angeles, CaliforniaAges 6 months–26 years - NCT07050823Recruiting
Studying chronic breathing issues and other health problems
This trial looks at how long-term health conditions like heart disease, diabetes, or high blood pressure might affect breathing problems. The goal is to better understand and help people with both issues.
São Carlos, São PauloAges 30 years+ - NCT07394959Recruiting
Guided hydration to protect kidneys in elderly heart patients
This trial tests a new way to manage fluids during heart procedures to prevent kidney injury. It uses a special vest that measures lung fluid to guide how much hydration you get.
Beijing, Beijing MunicipalityAges 60 years+ - NCT06863194RecruitingPhase 1/Phase 2
Probiotics and kidney disease progression trial
This trial tests whether taking a probiotic supplement can slow down the decline of kidney function in people with moderate chronic kidney disease (CKD stages 3 and 4). If you have stable kidney disease and are not already taking probiotics, joining this study could help researchers find a new way to protect your kidneys.
Al Mansurah, DakahliyaAges 18 years+ - NCT04375280Recruiting
Study of mobility problems in people with long-term illnesses
This study observes how people with chronic health conditions affect their ability to move and do everyday activities. It may help researchers better understand mobility limits and what factors influence them.
Clermont-FerrandAges 18–90 - NCT07519603Recruiting
Exercise program for older adults with COPD and frailty
This study tests whether a structured exercise and training program called VIVIFRAIL can help older adults with COPD feel stronger and more independent. You'll participate in guided physical activities designed to improve your strength and daily functioning.
Hanoi, HanoiAges 60 years+ - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+
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Common questions
- Are there clinical trials for chronic disease prevention?
- Yes. Clin2 currently lists 198 recruiting chronic disease prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.