Clinical trials
Primary Prevention clinical trials
Below are recruiting primary prevention clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06551038Recruiting
Suicide prevention program for at-risk teens
This study tests a new program to help prevent suicide in teens and young adults who face extra challenges. It is designed for those who are already struggling with mental health, school, detention, or other tough life situations.
Geneva, Canton of GenevaAges 14–25 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT07362056Recruiting
Suicide prevention for patients in Nepal primary care
This study tests a suicide prevention program for patients receiving care at government health facilities in Nepal's Bagmati Province. If you or a loved one are at risk for suicide and speak Nepali, this program may offer additional support through your regular clinic.
DolakhāAges 18 years+ - NCT06718322Enrolling by invitation
Large-scale cancer prevention program implementation study
This trial looks at how to improve the use of cancer prevention programs. It involves people who are already using a special planning tool to see how these programs can be adapted and put into practice more effectively.
TiranaAges 18 years+ - NCT05373940Recruiting
ICD placement to prevent sudden heart death in people over 70
This study looks at placing an ICD, a device that can stop dangerous heart rhythms, to help prevent sudden cardiac death. It is for people over 70 with specific heart function and heart failure symptoms.
Aix-en-ProvenceAges 70 years+ - NCT06810557Recruiting
Better sleep intervention to prevent obesity in kids
This trial tests a brief sleep program for children ages 6 to 11 who sleep less than 9 hours a night. The goal is to see if improving sleep can help prevent unhealthy weight gain. Eligible families will be randomly assigned to the sleep program or to a comparison group.
Philadelphia, PennsylvaniaAges 6–11 - NCT06792981Recruiting
Digital school program to prevent eating disorders in pre-teens
This trial tests a digital program for schools to help prevent eating disorders in pre-teens. It is designed for 5th and 6th graders and involves activities and questionnaires.
Santa Cruz de Tenerife, Santa Cruz de TenerifeAges 10–13 - NCT07230886Recruiting
Reducing transplant complications with enhanced preservation
This trial tests a new way to preserve donated lungs before transplant to lower the risk of complications. It may help primary graft dysfunction, a serious lung problem after surgery.
Toronto, OntarioAges 17 years+ - NCT05845489RecruitingPhase 4
Clopidogrel to prevent heart problems from minor artery plaque
This trial tests whether clopidogrel (a blood-thinning medicine) can prevent future heart attacks or strokes in people who have early, “subclinical” plaque in their heart arteries. You may be considered if scans show plaque but not major artery blockage that needs a procedure.
Seoul, OtherAges 40 years+ - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT07382583Recruiting
Study of a decision tool for endometrial cancer prevention
This study is developing a tool to help women decide if using a hormone-releasing intrauterine device (IUD) is right for them to lower their risk of endometrial cancer. Researchers are interviewing women at different risk levels and healthcare providers to make the tool useful and easy to understand.
Houston, TexasAges 18 years+ - NCT06503341Recruiting
Preventive cardiology patient registry
This study is a registry that collects information from people who visit preventive cardiology clinics. It helps doctors learn more about heart disease prevention and how to better care for patients.
Karachi, SindhAges 18–90 - NCT06905054RecruitingPhase 2
Preventing PSC recurrence after liver transplant
This trial tests whether fenofibrate can prevent primary sclerosing cholangitis (PSC) from coming back after a liver transplant. It is for adults who had a liver transplant for PSC between 1 and 7 years ago and have certain risk factors.
Scottsdale, ArizonaAges 18–75 - NCT06277063Recruiting
Nerve-stimulation device for headache in children and young adults
This trial tests if a gentle nerve-stimulating device worn on the neck (called nVNS) can prevent and treat common headaches like migraine, cluster, and tension-type headaches in children and young adults. If you often get headaches and want a drug-free option, this might help.
Guangzhou, GuangdongAges 7–20 - NCT06864468Recruiting
Preventing obesity in American Indian kids in rural schools
This trial studies a program to help prevent obesity in American Indian children. It includes a 3-day summer camp and focuses on healthy habits for 3rd and 4th graders in rural tribal schools.
Flagstaff, ArizonaAges 8–10 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT05198960RecruitingPhase 3
Blood thinner drugs vs aspirin to prevent clot problems
This trial compares apixaban or rivaroxaban (blood thinners) against aspirin to prevent future clot-related complications in people with certain bone marrow diseases (PV, ET, or pre-PMF) that have a specific JAK2 mutation. It may help lower the risk of clots, but it also carefully considers bleeding risk.
AngersAges 18 years+ - NCT06626178Recruiting
AI for preventing smoking-related diseases
This study uses artificial intelligence to analyze CT scans and other health data to better identify people at risk for smoking-related diseases like lung cancer. Researchers hope to improve early detection and prevention.
MilanAges 18 years+ - NCT05482386Recruiting
Blood and health traits study in older people on statins
This study looks at blood markers (“biomarkers”) to better understand health risk in older adults who have multiple long-term illnesses and are taking statin medicines. It may help researchers predict outcomes and improve care for people with complex health needs.
BernAges 70 years+ - NCT05725096Recruiting
CT scan helps guide cholesterol and heart risk care
This study is testing how a special heart scan (coronary CT angiography) can help manage cholesterol levels and other heart risk factors in people who feel well and have no known heart disease. It may help doctors better decide what lifestyle or medicines you may need to lower risk.
Nanjing, JiangsuAges 40–69 - NCT05482399Recruiting
Study statin use and silent artery plaque in older adults
This study looks at “subclinical atherosclerosis,” meaning early or silent plaque buildup in the arteries, in older people already taking statins. It may help doctors understand how well statins can slow artery damage in people with multiple health conditions.
BernAges 70 years+ - NCT04646252Recruiting
Testing a blood-surface feature to prevent heart problems
This study looks at whether a healthy blood lining (the glycocalyx) can help predict and reduce the risk of major heart events in people who have not yet had heart disease. You may be asked to do screening tests and share health information to see how these factors relate to future risk.
Athens, AtticaAges 18–85 - NCT06832644Recruiting
Heart risk prediction study for healthy adults in Italy
This study tests a new way to predict your future risk of heart disease. It is for healthy adults aged 40-80 who have never had heart problems or diabetes. You will use your email and internet to take part.
Milan, MilanAges 40–80 - NCT03770312RecruitingPhase 4
Testing low/moderate statin use to prevent heart problems in older adults
This study looks at whether taking a low- to moderate-dose statin can prevent first-time heart and stroke problems in people age 70 and older. It may help you lower “bad cholesterol” (LDL) and see if that leads to fewer heart events over time.
SeoulAges 70 years+
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Common questions
- Are there clinical trials for primary prevention?
- Yes. Clin2 currently lists 89 recruiting primary prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.