Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07361146Recruiting
Physical therapy during or before dialysis: a comparison
This study compares doing physical therapy during your dialysis session versus right before it. It looks at which timing might work better for people on hemodialysis.
HawalliAges 21–65 - NCT07662889Enrolling by invitation
Comparing two types of dialysis for kidney failure
This trial compares a newer type of dialysis called hemodiafiltration with standard hemodialysis to see if it improves certain health measures in people with end-stage kidney disease. It may help determine which method works better for long-term treatment.
Lahore, Punjab ProvinceAges 18–70 - NCT05835271Enrolling by invitation
Hip exoskeleton to help walking in severe lung disease
This trial tests a powered hip exoskeleton device to improve walking ability in people with stable, severe lung-related breathing problems. It may help you walk farther or more comfortably by supporting your movement, as long as your heart, blood pressure, and skin/body fit are safe for the device.
Toronto, OntarioAges 18 years+ - NCT07736872Recruiting
Sleep apnea screening in diverse groups
This study is screening people from different backgrounds for obstructive sleep apnea (a condition where breathing stops and starts during sleep). It uses a sleep test and questionnaires to see if you might have it.
Guangzhou, GuangdongAges 18–80 - NCT07512687Recruiting
Portable Oxygen During Daily Activity for Lung Disease
This study tests whether using portable oxygen during everyday activities helps people with certain lung diseases (like pulmonary fibrosis or COPD) who only experience low oxygen levels when moving around. Researchers want to see if a portable oxygen device improves how well participants can function and feel during daily life.
Buffalo, New YorkAges 18–85 - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT03120481Recruiting
Check how respiratory health changes in people without lung problems
This trial enrolls adults who recently had a chest X-ray as part of routine health screening and did not show major abnormal findings, and who do not have significant breathing symptoms. It may help researchers understand changes in respiratory health over time and improve how respiratory disease risk is monitored.
Seoul, SeoulAges 19–90 - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT05780762Recruiting
Nurse-led follow-up for long-term conditions in primary care
This study tests whether adding a specific nursing care approach improves partnership in health between patients and their care team. It’s for people with one or more stable long-term (chronic) conditions followed by an advanced practice nurse in primary care.
FirminyAges 18 years+ - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT06713512Recruiting
Estrogen and its effect on lung tissue in obstructive lung disease
This study looks at how the hormone estrogen affects the lungs of people with asthma or COPD. It will help researchers understand why these diseases may be different in women.
LondonAges 18–99 - NCT06983847Recruiting
Long-term study of Vitamin-C Injektopas in vitamin C deficiency
This study observes patients with vitamin C deficiency who receive Vitamin-C Injektopas 7.5 g over time to understand how it is used and its effects. It may help if you have low vitamin C levels.
Vienna, Etc., AustriaAges 18–120 - NCT00307281Recruiting
Emphysema and COPD patient registry with sample storage
This study enrolls people who have emphysema/COPD into a research registry and collects health information and biological samples. It may help researchers understand the disease better and improve future treatments.
Pittsburgh, PennsylvaniaAges 21 years+ - NCT05318196Recruiting
Predict kidney disease risk and progression from patient data
This trial looks at ways to predict how kidney disease may develop, change, or cause complications using information from patients. It may help doctors identify people at higher risk and tailor care earlier.
ToulouseAges 18–99 - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT07169422Recruiting
Pharmacist prescribing for kidney care in type 2 diabetes
This study tests whether having a pharmacist prescribe kidney-protective medications works better than usual care for people with type 2 diabetes and early kidney disease. If you don't have a family doctor, you may be able to get these medications more easily through a pharmacist.
Halifax, Nova ScotiaAges 18 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Phoenix, ArizonaAges 18–90 - NCT07606703RecruitingPhase 2
Madecassoside for Hardened Skin After Bone Marrow Transplant
This trial tests whether a plant-derived medicine called madecassoside can help treat sclerotic chronic graft-versus-host disease (a hardening and tightening of the skin that sometimes happens after bone marrow transplant). You would take tablets and be monitored to see if your skin condition improves.
Wuhan, HubeiAges 14–65 - NCT06812767Enrolling by invitation
Chronic disease risks in working-age people
This study looks at risk factors for chronic diseases in healthy working-age adults. You may help researchers understand how to prevent conditions like heart disease or diabetes.
MoscowAges 18 years+ - NCT07613827Enrolling by invitation
AI screening for fatty liver disease using CT scans
This study uses artificial intelligence to help doctors identify fatty liver disease from CT scans you may already be having. If eligible, you'll have some blood tests and possibly an ultrasound or MRI to confirm liver health, helping catch liver disease early.
Shenyang, LiaoningAges 18 years+ - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT03326921RecruitingPhase 1
T cell treatment for leukemia after a bone marrow transplant
This early-phase trial tests an immune “T cell” therapy made to recognize a specific leukemia target. It is for people whose acute leukemia has come back (relapsed) or did not fully respond after receiving a donor stem cell transplant.
Seattle, WashingtonAges Up to 80 years - NCT07112235Recruiting
COPD and cold virus study
This study looks at how the common cold virus affects people with COPD to find new treatments. If you have moderate COPD and your symptoms flare up when you catch a cold, you may be able to help.
LondonAges 40–75
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,260 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.