Clinical trials
Chronic Insomnia Disorder clinical trials
Below are recruiting chronic insomnia disorder clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07695246Recruiting
Efficacy of CBT-I With Adjuvant Melatonin in Older Adults Chronic Insomnia
Hong KongAges 60 years+ - NCT07420816RecruitingPhase 2
Testing a new drug for insomnia
This trial tests a new medication, APSTZD, to see how well it works and how safe it is for people with insomnia, especially those who have trouble staying asleep through the night.
Bragança Paulista, São PauloAges 18–64 - NCT07595185Enrolling by invitation
Brain Stimulation to Improve Sleep in Chronic Insomnia
This study tests whether accelerated repetitive transcranial magnetic stimulation (rTMS)—a non-invasive brain stimulation technique—can improve sleep architecture and quality in people with chronic insomnia. The treatment may help you fall asleep faster and sleep longer without medication.
San Francisco, CaliforniaAges 18–85 - NCT07048600Recruiting
Brief trial of ACT-i for adults with chronic insomnia
This trial tests a psychological treatment called ACT-i for people with chronic insomnia (trouble sleeping for a long time). It aims to see if this online therapy can help improve sleep without drugs.
Cluj-NapocaAges 18–59 - NCT04545606Recruiting
Helping kids with autism sleep better by treating insomnia
This study looks for the best way to improve sleep in children with autism who have ongoing insomnia. You and your child will complete sleep tracking and participate in an insomnia treatment plan to reduce trouble falling asleep, staying asleep, or waking too early.
Columbia, MissouriAges 6–12 - NCT05618002Recruiting
Study compares sleep medicines for chronic pain insomnia
This trial tests different treatments to help people with long-term (chronic) pain and severe insomnia sleep better. It’s looking at three options—one medicine (lemborexant) compared with existing sleep medicines (zopiclone and clonidine)—and whether they improve sleep when non-medicine sleep strategies haven’t worked.
Surrey, British ColumbiaAges 20–99 - NCT05780177Recruiting
Brief behavioral therapy for insomnia in PTSD veterans
This trial tests a short, structured behavioral program to help improve sleep problems (insomnia) in veterans who also have posttraumatic stress disorder (PTSD). It may help you fall asleep easier and sleep more consistently while continuing your usual care when it’s stable.
San Francisco, CaliforniaAges 18–75 - NCT05813392Recruiting
Digital CBT for insomnia in breast cancer survivors
This trial tests a phone-based program (digital cognitive behavioral therapy for insomnia) to improve sleep and daytime functioning. It is for people with long-term insomnia who have finished breast cancer treatment and are currently stable.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06270121Recruiting
Mobile health app for healthy aging at home
This study is testing a mobile health app designed to help seniors live independently at home. If you join, you will use the app and answer surveys to see if it supports healthy aging.
SeoulAges 65 years+ - NCT06727448Recruiting
Testing a new French sleep regularity questionnaire
This study is testing a new French questionnaire about sleep regularity. You will wear a small device (actimetry) for 14 days as part of your regular sleep check-up, and fill out the questionnaire to help doctors see if it's a good tool.
BordeauxAges 18 years+ - NCT06767137Recruiting
Comparing two therapies for insomnia
This study compares two types of talk therapy — BRT (a brief version) and CBT-I (the standard approach) — to see which works better for people with insomnia. You would attend sessions and learn techniques to improve your sleep.
Bern, Canton of BernAges 18–80 - NCT06779149Recruiting
Comparing therapy and medication for chronic insomnia
This trial compares two treatments for chronic insomnia: cognitive behavioral therapy (CBT-I) and a medication called lemborexant. It aims to find which works better for different types of insomnia. You may qualify if you have ongoing trouble sleeping and are not taking other sleep aids.
Québec, QuebecAges 18 years+ - NCT06797284Recruiting
Light, electrical, and magnetic therapy for sleep issues
This study tests if light, electrical, or magnetic treatments can help people with insomnia, narcolepsy, or REM sleep behavior disorder improve their sleep-wake problems. It compares these gentle brain stimulation methods to understand which works best.
Suzhou, JiangsuAges 8–75 - NCT06926348Recruiting
Testing a digital sleep aid for chronic insomnia
This study tests a digital sleep aid (a smartphone program) to see if it's easy to use and helps improve sleep. If you have chronic insomnia and own a compatible device, you may be able to join.
Verona, VeronaAges 18–70 - NCT06967974Recruiting
Tai chi for chronic insomnia with anxiety
This trial tests whether practicing tai chi can help people with chronic insomnia who also feel anxious or on edge. You'll learn tai chi movements to improve sleep and calm your mind.
BeijingAges 18 years+ - NCT06972303RecruitingPhase 1/Phase 2
Mindfulness meditation for insomnia
This trial tests if a mindfulness meditation program, delivered through a mobile app, can help people with chronic insomnia fall asleep faster. You will use your own smartphone or tablet to follow the program and report your sleep.
Boston, MassachusettsAges 18 years+ - NCT07419152Recruiting
Yoga for chronic insomnia
This study tests whether yoga can help people with chronic insomnia sleep better. You will practice yoga regularly and see if it improves your sleep quality.
New Delhi, National Capital Territory of DelhiAges 18–65 - NCT07429578Recruiting
Brain stimulation for anxiety and insomnia
This study tests whether a gentle, non-invasive brain stimulation technique (tACS) can help people who have both generalized anxiety and long-term sleep problems. It aims to see if this treatment can reduce anxiety and improve sleep.
São Paulo, São PauloAges 18–65 - NCT07486882Recruiting
Comparing two insomnia treatments: sound therapy vs. cognitive behavioral therapy
This study compares a new sound-based therapy (Acoustic Resonance Therapy) using a headband to standard cognitive behavioral therapy for insomnia. It aims to see which approach helps people with moderate-to-severe insomnia sleep better.
Rochester, MinnesotaAges 22 years+ - NCT07542756RecruitingPhase 4
Testing Common Sleep Medications for Insomnia
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Philadelphia, PennsylvaniaAges 18–80 - NCT07495189Enrolling by invitation
Mood, sleep, and brain study
This trial looks at how mood problems and sleep issues affect each other. It compares people with and without these conditions to understand the connection.
Jinan, ShandongAges 18–80 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06281756RecruitingEarly Phase 1
CBT and Trazodone for Sleep and Blood Pressure in Insomnia
This trial tests whether cognitive behavioral therapy (a type of talk therapy for sleep) and/or the medication trazodone can improve sleep and lower blood pressure in people with chronic insomnia. You must be 18 or older and have ongoing trouble sleeping.
Denver, ColoradoAges 18 years+ - NCT06658171Recruiting
Relaxation training for chronic insomnia with anxiety
This study tests whether a relaxation training program and sleep habit changes can help people with chronic insomnia and anxiety. It aims to understand how these techniques improve sleep patterns and reduce anxiety.
BeijingAges 18–65
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Common questions
- Are there clinical trials for chronic insomnia disorder?
- Yes. Clin2 currently lists 69 recruiting chronic insomnia disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic insomnia disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic insomnia disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.