Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06501222Recruiting
Remote ischemic preconditioning for kidney protection in CKD
This study tests whether a simple, non-invasive treatment called remote ischemic preconditioning (RIC) can help protect the kidneys of people with chronic kidney disease. RIC involves briefly restricting blood flow to one arm using a blood pressure cuff, which may trigger the body's own protective response.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06879340RecruitingPhase 1
Testing a new CAR-T therapy for B-cell blood cancers
This study tests a new CAR-T cell therapy called DuoCAR20.19.22-D95 for people with certain blood cancers (like lymphoma and ALL) that have come back or haven't responded to multiple treatments. It aims to see if this therapy is safe and can help shrink or control the cancer.
Westwood, KansasAges 18 years+ - NCT07617376RecruitingPhase 4
Flu shot before leaving hospital after heart problems
This study tests whether giving a flu vaccine to patients before they leave the hospital after a heart condition improves their health. The vaccine may help protect your heart and prevent serious flu complications while you recover.
WroclawAges 18 years+ - NCT06419062Enrolling by invitation
Using wearables to monitor COPD at home
This study tests if a wearable device can help track your COPD symptoms between doctor visits. You'll use a smartphone or computer to share data, which may help your care team stay on top of your health.
GlasgowAges 18 years+ - NCT06419036Enrolling by invitation
Using medical devices to monitor COPD at home
This study tests whether wearable medical devices can help monitor your COPD symptoms at home. You will use a smartphone app and a small chest patch to track your breathing, which may help you and your doctor better manage your condition.
GlasgowAges 18 years+ - NCT05432635RecruitingPhase 1
CAR T-cell and vaccine treatment after stem cell transplant
This Phase 1 study tests a customized immune-cell treatment (CAR T-cells) plus a vaccine given after stem cell transplant for certain aggressive B-cell non-Hodgkin lymphomas. It aims to help your immune system better recognize and attack the lymphoma and to see how safe the approach is.
Duarte, CaliforniaAges 18 years+ - NCT05977283Recruiting
Follow-up study for people whose hepatitis B test improved
This study follows people with hepatitis B (HBV) blood tests that have improved over the last year. It aims to learn what happens after the hepatitis B surface antigen (HBsAg) goes down, and may help doctors better predict outcomes.
Guangzhou, GuangdongAges 18–65 - NCT06785506Recruiting
Personalized heart failure treatment using multiple biomarkers
This trial tests if using a combination of biomarkers can help personalize treatment for people with a specific type of heart failure called HFpEF (or heart failure with preserved ejection fraction). It aims to find better treatments based on your individual test results.
Alkmaar, North HollandAges 18 years+ - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07542756RecruitingPhase 4
Testing Common Sleep Medications for Insomnia
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Philadelphia, PennsylvaniaAges 18–80 - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06559735Recruiting
Brain oxygen measurement in chronic pain with spinal cord stimulation
This trial tests a new device to measure oxygen levels in the brain of people with chronic pain who are receiving spinal cord stimulation. It aims to see if brain oxygen changes can help manage pain better.
Walnut Creek, CaliforniaAges 18 years+ - NCT04557995Recruiting
Blood-filter treatment for chronic high-altitude sickness
This trial studies “erythrocytapheresis,” a procedure that filters part of the blood, to improve symptoms of chronic mountain sickness caused by long-term living at high altitude. It may help people with high-altitude–related headaches, dizziness, shortness of breath, poor sleep, fatigue, and related signs.
Xigazê, TibetAges 18 years+ - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+ - NCT05895136RecruitingPhase 2
Albumin plus blood thinner for severe cirrhosis after hospital recovery
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
ClichyAges 18–80 - NCT07753122Recruiting
Hydrogen water for chronic fatigue syndrome
This trial tests whether drinking hydrogen water can help with symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). If you have ME/CFS, this study might show if hydrogen water is a helpful treatment.
Stony Brook, New YorkAges 18–65 - NCT07387952Recruiting
Fecal transplant with nutrition help for chronic constipation
This trial tests if a fecal microbiota transplant combined with nutritional support can improve chronic constipation that hasn't gotten better with standard treatments. It's a small early study to see if the approach is safe and works.
BeijingAges 18–70 - NCT06244628RecruitingPhase 3
Study of Iguratimod for chronic graft-versus-host disease
This trial tests an experimental drug called Iguratimod for people with chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It aims to see if the drug can safely control cGVHD symptoms when other treatments haven't worked well enough.
Xuzhou, JiangsuAges 18–60 - NCT07353034Recruiting
Social Support for COPD Self-Management
This trial studies whether social support from friends, family, or community can help you better manage your COPD at home. You'll be asked to use online tools and report how you're doing.
Charleston, South CarolinaAges 40 years+ - NCT06418282Recruiting
Portable compression device for leg swelling
This study tests a new portable device that wraps around your leg to gently squeeze and reduce swelling from lymphedema or vein problems. It aims to see if at-home use can improve symptoms and lower healthcare costs compared to standard care.
New York, New YorkAges 18–100 - NCT07249346RecruitingPhase 2
Preventing GVHD after stem cell transplant with three drugs
This trial tests a three-drug combination (cyclophosphamide, tacrolimus, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant. It is for people with certain blood cancers who have a matched donor and can tolerate high-dose chemotherapy.
Columbus, OhioAges 18 years+ - NCT06824649RecruitingPhase 4
Comparing biologics for chronic sinusitis with nasal polyps
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
Portland, OregonAges 18 years+ - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT05598723RecruitingPhase 3
Botox versus Xeomin for chronic migraine in adults
This Phase 3 study compares two headache injections—Botox and Xeomin—for people with chronic migraine. It may help find out which option works better to reduce frequent, long-lasting migraine days.
Jacksonville, North CarolinaAges 18–89
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Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 209 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.