Clinical trials
Chronic Rhinosinusitis With Nasal Polyps clinical trials
Below are recruiting chronic rhinosinusitis with nasal polyps clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT06118554Recruiting
Testing a 3D-printed tool for better sinus rinses
This study tests whether a 3D-printed tool can help people with chronic sinusitis get better results from nasal rinses. It might help if your sinus rinses don't reach deep enough into your nasal passages.
Columbus, OhioAges 18–75 - NCT07134686Recruiting
Combined lung and ear-nose-throat care for asthma and sinusitis
This trial tests if seeing a lung specialist and an ear-nose-throat doctor together in one visit helps people with asthma and chronic sinusitis (with nasal polyps) feel better than seeing each specialist separately. You may qualify if your asthma or sinusitis is not well-controlled and you've used steroid pills in the past year.
MarseilleAges 18 years+ - NCT06824649RecruitingPhase 4
Comparing biologics for chronic sinusitis with nasal polyps
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
Portland, OregonAges 18 years+ - NCT07714525RecruitingPhase 2
Steroid nanocapsules after nasal surgery
This trial tests whether a new form of steroid (triamcinolone) delivered in tiny capsules can improve healing after common nasal surgeries for chronic sinusitis or nasal polyps.
Minya, Menia GovernorateAges 18–60 - NCT02975310Recruiting
In-clinic endoscopy surgery for chronic sinus polyps
This trial tests an in-clinic (not hospital) endoscopic procedure to remove nasal polyps in people with chronic sinus inflammation, after usual medicines haven’t helped. It may help reduce nasal blockage and improve sinus symptoms, while comparing safety and outcomes after the procedure.
Vancouver, British ColumbiaAges 18 years+ - NCT03725956Recruiting
Sleep study before and after nasal polyp surgery
This study uses a sleep test to look at breathing and sleep patterns in people with nasal polyps who need surgery because medicine didn’t help. It may help doctors understand how nasal polyps affect sleep and how surgery changes those sleep measurements.
LilleAges 18 years+ - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99 - NCT05708300Recruiting
Testing how mepolizumab works for people with nasal polyps
This study looks at blood and other measures (biomarkers) to understand how well mepolizumab helps people with nasal polyps, with or without asthma. It aims to find response clues that could help personalize treatment in the future.
Thessaloniki, ExochiAges 18 years+ - NCT05902325RecruitingPhase 4
Testing who benefits most from mepolizumab for nasal polyps
This study looks at why some people with severe chronic nasal polyps respond better to mepolizumab. It may help doctors predict who will benefit from the medicine, and who may need a different plan.
Montreal, QuebecAges 18 years+ - NCT06129552Recruiting
Healthy nose cells study for sinusitis insight
This study is looking at healthy people to understand how certain cells in the nose work. It will compare them to people with sinus problems to learn what goes wrong in chronic sinusitis with nasal polyps.
LeuvenAges 18 years+ - NCT06501807Recruiting
Biologics for severe nasal polyps: a French registry study
This study follows patients in France who are receiving biologic treatments for severe nasal polyps with chronic sinusitis. It collects information on how well these treatments work and their side effects over time.
LilleAges 18 years+ - NCT06892704Recruiting
Dupilumab smell restoration study for CRSwNP
This study tests if the medication dupilumab can improve smell loss in people with chronic sinusitis and nasal polyps. Researchers will check if blocking in the nose and electrical signals in the brain can predict who will benefit.
Chicago, IllinoisAges 18–65 - NCT07268313RecruitingPhase 4
Remission Check for Nasal Polyp Patients on Biologics
This study looks at patients with nasal polyps and chronic sinusitis who have been stable on a biologic medicine (Dupilumab or Mepolizumab) for at least 3 months. It checks if they stay in remission (symptoms well controlled, no need for extra treatments) for a full year.
Copenhagen, Region HAges 18 years+ - NCT07399665Recruiting
Tezepelumab for chronic sinusitis with nasal polyps in Russia
This study tracks how well tezepelumab works for people with chronic sinusitis and nasal polyps in real-world settings. It aims to see if this medication reduces symptoms and the need for surgery.
Kazan'Ages 18 years+ - NCT05531630Enrolling by invitation
Xylitol versus saline rinses for sinus symptoms in adults with CF
This study compares two kinds of nasal rinse packets—xylitol versus plain saline—to see which better reduces sinus symptoms. It may help adults with cystic fibrosis and long-term sinus inflammation feel better with routine, at-home nasal care.
LeuvenAges 18 years+ - NCT06970977Recruiting
Chronic sinusitis questionnaire validation study
This study is testing a new questionnaire to better understand chronic sinusitis symptoms. It may help improve how doctors diagnose and treat the condition.
Santa Monica, CaliforniaAges 18 years+ - NCT06960876Recruiting
Ultrasound vs. sinus massage for chronic sinusitis
This study compares two treatments for chronic sinusitis: ultrasound therapy (sound waves applied to the face) and sinus massage (gentle pressure on the face). Both are non-drug options that may help relieve your symptoms.
IslamabadAges 20–60 - NCT02038166Recruiting
Measuring nasal function in adults with chronic sinus symptoms
This study tests a specialized way of measuring how your nasal lining responds in people with chronic rhinosinusitis (long-lasting sinus inflammation). The goal is to see whether the nasal measurement is usable and safe, and to help better understand chronic sinus disease.
Birmingham, AlabamaAges 18 years+ - NCT07073664Enrolling by invitation
Endoscopic sinus expansion plus Stapokibart for chronic sinusitis
This trial tests if a new drug (Stapokibart) combined with a sinus surgery improves symptoms like nasal congestion, discharge, and loss of smell in people with type 2 chronic sinusitis.
Changchun, JilinAges 18–75 - NCT05494346Recruiting
Seawater nasal spray with essential oils for blocked nose
This trial tests whether a seawater nasal spray (with essential oils) is safe and works well for people ages 12+ who have sudden (acute) cold- or allergy-related nasal blockage. You may be able to join if you can use the spray as instructed and complete simple monitoring and questionnaires.
Blainville-sur-OrneAges 12 years+ - NCT06580210Recruiting
Seawater spray with essential oils for stuffy nose
This trial tests a seawater and essential oil spray to clear a stuffy nose caused by a cold, sinus infection or allergies. The spray is meant to help you breathe easier without strong medicines.
BayeuxAges 12 years+ - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT06567821RecruitingPhase 2/Phase 3
Using navigation to improve balloon sinus surgery accuracy
This trial tests whether using a navigation system during balloon sinus surgery makes the procedure more accurate for people with chronic sinusitis. It may help improve outcomes for those who have not had sinus surgery before.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for chronic rhinosinusitis with nasal polyps?
- Yes. Clin2 currently lists 49 recruiting chronic rhinosinusitis with nasal polyps studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic rhinosinusitis with nasal polyps trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic rhinosinusitis with nasal polyps trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.