Clinical trials
Circadian Rhythm clinical trials
Below are recruiting circadian rhythm clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06669507Recruiting
Sleep clinic study on non-drug treatment options
This study looks at how people with certain sleep disorders respond to non-medication treatments. If you have trouble with your sleep-wake cycle and would like behavioral or lifestyle help instead of drugs, this trial might be for you.
TrondheimAges 18 years+ - NCT06701396RecruitingPhase 3
Tasimelteon for delayed sleep phase disorder with genetic variant
This study tests a new sleep medication called tasimelteon compared to a placebo (inactive treatment) for people with a specific sleep disorder linked to a genetic change in the body's internal clock. If you have Delayed Sleep-Wake Phase Disorder and carry the CRY1Δ11 variant, this trial may help improve your sleep timing.
Çankaya, AnkaraAges 18–75 - NCT07685262Recruiting
Bright light therapy for better daytime function in students
This trial tests if morning bright light therapy can help university students feel more awake and function better during the day. You may be eligible if you live in shared student housing and don't have a diagnosed sleep problem.
Hung HomAges 18 years+ - NCT06727448Recruiting
Testing a new French sleep regularity questionnaire
This study is testing a new French questionnaire about sleep regularity. You will wear a small device (actimetry) for 14 days as part of your regular sleep check-up, and fill out the questionnaire to help doctors see if it's a good tool.
BordeauxAges 18 years+ - NCT06803446Recruiting
How does daily rhythm affect blood sugar during exercise in type 1 diabetes?
This study looks at how the time of day affects blood sugar control during moderate exercise and intense activity in teens with type 1 diabetes. It may help find the best times for exercise to manage glucose better.
Loos, NordAges 10–16 - NCT06832007Recruiting
Light therapy for recovery from opioid use disorder
This study tests whether a special light device used at home can improve recovery in people being treated for opioid use disorder. It looks at how light might help with sleep, mood, and overall well-being.
Birmingham, AlabamaAges 18–60 - NCT06880029RecruitingPhase 1/Phase 2
Timing of chemo and immunotherapy for breast cancer
This trial is testing whether the time of day you receive chemotherapy and pembrolizumab (immunotherapy) affects how well they work against triple-negative breast cancer. It's for people who will get these treatments before surgery.
Vila Nova de Gaia, RegiãoAges 18–75 - NCT06891534Recruiting
Circadian rhythms in human fat tissue study
This study looks at how your body's internal clock affects fat tissue. It compares people with different BMIs to understand how circadian rhythms work in fat cells.
Rochester, MinnesotaAges 18–55 - NCT07224971RecruitingPhase 2
Timing of immunotherapy for advanced cancer
This trial tests whether the time of day you receive immunotherapy (in the morning vs. later) affects how well it works. It is for people with advanced lung cancer or other solid tumors who are just starting or continuing PD-1/PD-L1 inhibitor treatment.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07249918Recruiting
Wearable devices for dementia care in rural Taiwan
This trial tests if wearable devices can help monitor and improve behavioral symptoms like agitation, depression, or sleep problems in people with Alzheimer's or mild cognitive impairment. It also involves their caregivers.
Beigang, YunlinAges Any age - NCT07677111Recruiting
Chronotype alignment and time perception study
This study explores how your natural sleep-wake pattern (chronotype) affects the way you perceive time. If you are a clear early bird or night owl, you may be invited to attend one early-morning and one late-evening session.
Hong KongAges 18–55 - NCT07410585Recruiting
Matching body clock to daily life for student well-being
This study tests if an app that helps match your daily schedule to your body's natural sleep-wake clock can improve well-being and happiness in college students. If you are a UCSD undergraduate with an Apple device, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07410936Recruiting
Self-Acupressure for Social Jet Lag in Female Students
This study tests whether a daily self-acupressure routine (gently pressing on specific points on your body) can help reduce social jet lag—the mismatch between your sleep schedule on school days versus free days—in female health-science students. It involves a 12-week home practice and tracking your sleep quality.
Niğde, MerkezAges 18–25 - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07545499Recruiting
Daily rhythms and physical recovery after COVID-19
This study looks at how your body's natural daily rhythms (sleep-wake cycles, energy patterns) affect physical function and daily activities in people recovering from long COVID. Understanding these patterns may help develop better recovery strategies.
Ankara, AltindağAges 18–65 - NCT07222449Enrolling by invitation
Wearable devices and blood tests for sleep in Alzheimer's
This study uses wrist monitors and blood tests to understand sleep problems in people with Alzheimer's dementia. It aims to improve sleep management through digital therapy and personalized insights.
Beigang, YunlinAges Any age - NCT06706453Enrolling by invitation
Sleep survey for medical trainees
This study asks medical trainees about their sleep patterns as part of an online survey. It aims to understand how on-call work and training roles affect sleep in healthcare staff.
LondonAges 18 years+ - NCT06505005Enrolling by invitation
Pain Relief Patch for Muscle Pain and Better Sleep
This study tests whether a pain relief patch worn on the skin can help with moderate back, shoulder, or other muscle pain and improve sleep. You will be given either the active patch or a placebo patch to wear.
Tyrone, GeorgiaAges 18–65 - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65
Hear when a new Circadian Rhythm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for circadian rhythm?
- Yes. Clin2 currently lists 69 recruiting circadian rhythm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a circadian rhythm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a circadian rhythm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.