Clinical trials
Circadian Rhythm clinical trials
Below are recruiting circadian rhythm clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06502613Recruiting
Scoliosis and Sleep Cycle in Children
This study looks at how sleep timing (melatonin levels) might be linked to new cases of scoliosis in children. If you have scoliosis and are between 6 and 15, you may help researchers understand this connection.
Wenzhou, ZhejiangAges 6–15 - NCT07791472Recruiting
Delirium and light: a pilot study on risk factors
This study looks at why some patients in intensive care develop confusion (delirium) and whether light exposure affects it. It may help improve care for older patients in the hospital.
LondonAges 50 years+ - NCT07785960Enrolling by invitation
Sleep tracking with a special patch after night shifts
This trial tests a patch that you wear while sleeping after a night shift to see if it helps you recover and tracks your sleep. You will also wear a sleep tracker on your wrist.
Birmingham, West MidlandsAges 18 years+ - NCT07715721Recruiting
Acupuncture and Traditional Chinese Medicine for Sarcopenia and Sleep Problems in Older Adults
This study looks at how Traditional Chinese Medicine body types and sleep patterns relate to muscle loss (sarcopenia) in older adults, and tests whether acupoint stimulation (like acupuncture without needles) can help.
TainanAges 20 years+ - NCT05277532Recruiting
Exercise and sleep timing for overweight type 1 diabetes
This trial studies whether changing daily sleep timing (circadian rhythm) and doing physical exercise can improve health outcomes in people who are overweight and have type 1 diabetes (or in some healthy people). It may help by seeing what combinations of routine and activity are most beneficial.
StockholmAges 18–50 - NCT07685262Recruiting
Bright light therapy for better daytime function in students
This trial tests if morning bright light therapy can help university students feel more awake and function better during the day. You may be eligible if you live in shared student housing and don't have a diagnosed sleep problem.
Hung HomAges 18 years+ - NCT07677111Recruiting
Chronotype alignment and time perception study
This study explores how your natural sleep-wake pattern (chronotype) affects the way you perceive time. If you are a clear early bird or night owl, you may be invited to attend one early-morning and one late-evening session.
Hong KongAges 18–55 - NCT06701396RecruitingPhase 3
Tasimelteon for delayed sleep phase disorder with genetic variant
This study tests a new sleep medication called tasimelteon compared to a placebo (inactive treatment) for people with a specific sleep disorder linked to a genetic change in the body's internal clock. If you have Delayed Sleep-Wake Phase Disorder and carry the CRY1Δ11 variant, this trial may help improve your sleep timing.
Çankaya, AnkaraAges 18–75 - NCT07558642Recruiting
Nerve Block to Reduce Confusion in Older ICU Patients
This study tests whether a nerve-blocking injection (stellate ganglion block) can reduce confusion and help restore normal sleep-wake cycles in older adults staying in the intensive care unit. Researchers hope this treatment may help patients recover faster and feel more alert.
Antalya, MuratpaşaAges 65–99 - NCT07545499Recruiting
Daily rhythms and physical recovery after COVID-19
This study looks at how your body's natural daily rhythms (sleep-wake cycles, energy patterns) affect physical function and daily activities in people recovering from long COVID. Understanding these patterns may help develop better recovery strategies.
Ankara, AltindağAges 18–65 - NCT07534670Recruiting
Tracking lifestyle and blood sugar patterns in early pregnancy
This study follows pregnant women in their first trimester to understand how daily habits like sleep, activity, and eating affect blood sugar levels. The goal is to learn more about metabolic health during pregnancy and potentially prevent complications.
Singapore, SingaporeAges 21–39 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT07410936Recruiting
Self-Acupressure for Social Jet Lag in Female Students
This study tests whether a daily self-acupressure routine (gently pressing on specific points on your body) can help reduce social jet lag—the mismatch between your sleep schedule on school days versus free days—in female health-science students. It involves a 12-week home practice and tracking your sleep quality.
Niğde, MerkezAges 18–25 - NCT07410585Recruiting
Matching body clock to daily life for student well-being
This study tests if an app that helps match your daily schedule to your body's natural sleep-wake clock can improve well-being and happiness in college students. If you are a UCSD undergraduate with an Apple device, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07315074Recruiting
Esketamine for better sleep after surgery in postmenopausal women
This trial tests if a low dose of esketamine, given during anesthesia, can improve sleep quality after lower-limb fracture surgery in postmenopausal women. It aims to find a safe way to help you rest better after your operation.
Jingjiang, JiangsuAges 45 years+ - NCT06880029RecruitingPhase 1/Phase 2
Timing of chemo and immunotherapy for breast cancer
This trial is testing whether the time of day you receive chemotherapy and pembrolizumab (immunotherapy) affects how well they work against triple-negative breast cancer. It's for people who will get these treatments before surgery.
Vila Nova de Gaia, RegiãoAges 18–75 - NCT07249918Recruiting
Wearable devices for dementia care in rural Taiwan
This trial tests if wearable devices can help monitor and improve behavioral symptoms like agitation, depression, or sleep problems in people with Alzheimer's or mild cognitive impairment. It also involves their caregivers.
Beigang, YunlinAges Any age - NCT07224971RecruitingPhase 2
Timing of immunotherapy for advanced cancer
This trial tests whether the time of day you receive immunotherapy (in the morning vs. later) affects how well it works. It is for people with advanced lung cancer or other solid tumors who are just starting or continuing PD-1/PD-L1 inhibitor treatment.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07222449Enrolling by invitation
Wearable devices and blood tests for sleep in Alzheimer's
This study uses wrist monitors and blood tests to understand sleep problems in people with Alzheimer's dementia. It aims to improve sleep management through digital therapy and personalized insights.
Beigang, YunlinAges Any age - NCT06384742Recruiting
Sleep help for nurses working night shifts
This study tests a program to help nurses and nursing staff who work night shifts improve their sleep. It's a 6-month online program that may help you sleep better and feel more rested.
Corvallis, OregonAges 18–65 - NCT06891534Recruiting
Circadian rhythms in human fat tissue study
This study looks at how your body's internal clock affects fat tissue. It compares people with different BMIs to understand how circadian rhythms work in fat cells.
Rochester, MinnesotaAges 18–55 - NCT06832007Recruiting
Light therapy for recovery from opioid use disorder
This study tests whether a special light device used at home can improve recovery in people being treated for opioid use disorder. It looks at how light might help with sleep, mood, and overall well-being.
Birmingham, AlabamaAges 18–60
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Common questions
- Are there clinical trials for circadian rhythm?
- Yes. Clin2 currently lists 69 recruiting circadian rhythm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a circadian rhythm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a circadian rhythm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.