Clinical trials
Circadian Rhythm Disorders clinical trials
Below are recruiting circadian rhythm disorders clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07317349Recruiting
A study on how a daily time shift affects body rhythms in couples
This study looks at how a small, consistent delay in your daily schedule affects your body's internal clock. It involves you and your partner staying together in a lab for five days.
AarhusAges 23–45 - NCT07702344Recruiting
Shift work and your body's daily rhythm
This study looks at how shift work affects your body's natural daily rhythm (circadian rhythm) and overall health. It may help find ways to support the health of shift workers like you.
IstanbulAges 18–65 - NCT04966351Recruiting
Study countermeasures for disrupted body clock timing
This study tests ways to help your body’s internal clock stay in sync when your sleep timing is off. It’s looking for healthy adults with fairly regular sleep and certain lifestyle and location history.
Fort Collins, ColoradoAges 18–35 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT06288568Recruiting
Night shift work and obesity risk study
This study looks at how night shift work affects weight and health in hospital and factory workers. They want to see if working nights changes your body's hormones and risk for obesity.
Vienna, State of ViennaAges 21 years+ - NCT06669507Recruiting
Sleep clinic study on non-drug treatment options
This study looks at how people with certain sleep disorders respond to non-medication treatments. If you have trouble with your sleep-wake cycle and would like behavioral or lifestyle help instead of drugs, this trial might be for you.
TrondheimAges 18 years+ - NCT06701396RecruitingPhase 3
Tasimelteon for delayed sleep phase disorder with genetic variant
This study tests a new sleep medication called tasimelteon compared to a placebo (inactive treatment) for people with a specific sleep disorder linked to a genetic change in the body's internal clock. If you have Delayed Sleep-Wake Phase Disorder and carry the CRY1Δ11 variant, this trial may help improve your sleep timing.
Çankaya, AnkaraAges 18–75 - NCT06727448Recruiting
Testing a new French sleep regularity questionnaire
This study is testing a new French questionnaire about sleep regularity. You will wear a small device (actimetry) for 14 days as part of your regular sleep check-up, and fill out the questionnaire to help doctors see if it's a good tool.
BordeauxAges 18 years+ - NCT06505005Enrolling by invitation
Pain Relief Patch for Muscle Pain and Better Sleep
This study tests whether a pain relief patch worn on the skin can help with moderate back, shoulder, or other muscle pain and improve sleep. You will be given either the active patch or a placebo patch to wear.
Tyrone, GeorgiaAges 18–65 - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT06471374Recruiting
Circadian rhythm in delayed sleep-wake phase disorder
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
Boulder, ColoradoAges 16–40 - NCT06832007Recruiting
Light therapy for recovery from opioid use disorder
This study tests whether a special light device used at home can improve recovery in people being treated for opioid use disorder. It looks at how light might help with sleep, mood, and overall well-being.
Birmingham, AlabamaAges 18–60 - NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT04578249Recruiting
Blocking blue light at night after heart surgery
This trial tests whether reducing blue light at night after certain planned heart surgeries helps protect mood, thinking, and recovery. If you have no history of major mental health problems or organ problems, you may be able to join the study.
Morgantown, West VirginiaAges 45–75 - NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT06370962Recruiting
Sleep study for children with cystic fibrosis on Kaftrio-Kalydeco
This study looks at sleep and daily activity rhythms in children with cystic fibrosis who are taking a medication called Kaftrio-Kalydeco. It aims to understand if the medication affects sleep patterns and how to improve them.
BronAges 2–17 - NCT06473415Recruiting
Lormetazepam for sleep in the ICU
This trial tests whether a sleep medication called lormetazepam can improve sleep quality and brain activity in ICU patients who are on a breathing machine. It may help if you need sedation and are expected to stay in the ICU for at least two days.
Mitte, State of BerlinAges 18–100 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65 - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT06384742Recruiting
Sleep help for nurses working night shifts
This study tests a program to help nurses and nursing staff who work night shifts improve their sleep. It's a 6-month online program that may help you sleep better and feel more rested.
Corvallis, OregonAges 18–65 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06226025RecruitingPhase 2
Melatonin for Bipolar Disorder in Night Owls
This trial tests whether giving melatonin at the right time can help people with bipolar disorder who are night owls improve their mood and sleep. You would take melatonin or a placebo each evening for a few weeks while tracking your symptoms on a phone app.
Ann Arbor, MichiganAges 18–60
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Common questions
- Are there clinical trials for circadian rhythm disorders?
- Yes. Clin2 currently lists 53 recruiting circadian rhythm disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a circadian rhythm disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a circadian rhythm disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.