Clinical trials
CKD Stage 4 clinical trials
Below are recruiting ckd stage 4 clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07494045RecruitingPhase 2
Study of CTAP101 for kids with chronic kidney disease
This study tests a new extended-release capsule (CTAP101) for children aged 8 to under 18 with moderate to severe chronic kidney disease (CKD). The goal is to see how the drug works in the body, if it's safe, and if it can help control mineral and hormone levels that are often out of balance in CKD.
Kansas City, MissouriAges 1 month–17 years - NCT06982079RecruitingPhase 3
SGLT2 inhibitors for advanced kidney disease
This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.
CairoAges 18 years+ - NCT06799936Recruiting
Helping older adults with kidney disease make treatment choices
This study tests a program that helps older adults with advanced chronic kidney disease talk with their doctors about treatment options, like dialysis, palliative care, or a kidney transplant. It aims to make sure patients' values and preferences are heard in these important decisions.
Hong KongAges 65 years+ - NCT06182839RecruitingPhase 2
Canagliflozin for advanced kidney disease with MRI study
This trial tests if canagliflozin, a diabetes medication, can help people with very advanced kidney disease or who recently started dialysis. It uses MRI scans to see how the drug affects the heart and kidneys.
Montreal, QuebecAges 18 years+ - NCT07624305RecruitingPhase 3
Balcinrenone and Dapagliflozin for Moderate-to-Severe Kidney Disease
This study tests a combination of two medications (balcinrenone and dapagliflozin) to help protect your kidneys if you have moderate-to-severe chronic kidney disease. The trial evaluates whether this combination slows kidney damage and improves kidney health.
Huntsville, AlabamaAges 18–99 - NCT05508009RecruitingPhase 1/Phase 2
Kidney transplant with donor-matched stem cell treatment
This early-phase trial tests a stem cell transplant from a donor who is an extremely close match, given to people who are about to receive a kidney transplant from the same donor. The goal is to improve how well the new kidney works by resetting the immune system to better accept the transplant.
Palo Alto, CaliforniaAges 1–30 - NCT02938611Recruiting
Study to estimate care needs for stage 4 kidney disease
This study aims to find out how common stage 4 kidney disease is in a specific area and how it is being managed. It may help doctors plan better care by improving local estimates and understanding current treatment approaches.
AlèsAges Any age - NCT05510323RecruitingPhase 3
Immunosuppressive treatment for IgA kidney disease in stage 3–4
This trial tests whether immunosuppressive therapy (medicine that calms the immune system) helps people with IgA nephropathy and moderately to severely reduced kidney function. It is intended for adults with confirmed IgA kidney disease who still have significant protein in the urine despite standard blood-pressure kidney protection treatment.
Xi'anAges 18 years+ - NCT07187713RecruitingPhase 4
Study of ACE Reno, Pico Cell Matrix for kidney health
This trial tests a new treatment called ACE Reno, Pico Cell Matrix to see if it can improve kidney function in people with chronic kidney disease (CKD) at various stages. It may be an option if you have early to moderate kidney issues (including after a transplant) and are already on standard therapies.
Giza, GZAges 18–80 - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT05858437Recruiting
Testing propionic acid to improve immune function in children with kidney failure
This study tests whether propionic acid can help the immune system work differently in children with advanced chronic kidney disease who receive regular dialysis. It may help regulate immune cells, aiming for better immune function while keeping you medically stable.
BerlinAges 12–20 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT06224153Recruiting
Tracking Protein Intake in Advanced Kidney Disease
This study compares two ways to track how much protein you eat using a mobile app or website. It is for people with advanced chronic kidney disease who are already in a nutrition program and want to follow a low-protein diet.
Marseille, FranceAges 18 years+ - NCT07494266Recruiting
Potassium in plant-based diet for kidney patients
This trial tests whether a plant-based diet with more potassium is safe for people with advanced chronic kidney disease (CKD) compared to a plant-based diet with less potassium. It may help you understand how to manage your potassium levels while eating more plants.
Huddinge, Stockholm LänAges 20–85 - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT07221604Recruiting
Goal-setting for advanced kidney disease
This trial tests a program that helps patients with advanced kidney disease, their families, and their doctors work together to set care goals. The program aims to improve communication and quality of life.
Keene, New HampshireAges 18 years+ - NCT07187479Recruiting
Testing a new insulin approach for kidney disease and diabetes
This study tests a new approach to help your body use insulin better, which may improve blood sugar control and slow down kidney disease. It is for people with advanced chronic kidney disease and type 2 diabetes who are not yet on dialysis.
Phoenix, ArizonaAges 18 years+ - NCT07186218Recruiting
Symptom monitoring with feedback for advanced kidney disease
This study tests a symptom-monitoring system with feedback for people with advanced chronic kidney disease (CKD). The goal is to help manage symptoms and improve quality of life without needing dialysis or a transplant right away.
Boston, MassachusettsAges 18 years+ - NCT06360380Recruiting
Wearable device for fluid removal in heart failure
This trial tests a wearable device that removes extra fluid from your body without using the kidneys. It may help people with heart failure who still have fluid buildup despite taking high doses of water pills.
La Jolla, CaliforniaAges 21–79 - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT06933108Recruiting
Predicting Nerve Damage with Simple Function Tests
This study looks at whether simple function tests can predict nerve damage in people with advanced kidney disease or diabetes. It aims to find early signs of nerve problems before they become serious.
Le MansAges 60–80 - NCT07123909Recruiting
Immune adsorbent therapy for dialysis patients with inflammation
This study tests a therapy that absorbs inflammatory substances from the blood during dialysis. It may help people on dialysis who have ongoing inflammation, shown by high IL-6 or CRP levels.
MoscowAges 18 years+ - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT07662889Enrolling by invitation
Comparing two types of dialysis for kidney failure
This trial compares a newer type of dialysis called hemodiafiltration with standard hemodialysis to see if it improves certain health measures in people with end-stage kidney disease. It may help determine which method works better for long-term treatment.
Lahore, Punjab ProvinceAges 18–70
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Common questions
- Are there clinical trials for ckd stage 4?
- Yes. Clin2 currently lists 24 recruiting ckd stage 4 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ckd stage 4 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ckd stage 4 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.