Clinical trials
Clinical Trials clinical trials
Below are recruiting clinical trials clinical trials, each written for real people, not researchers. We’re tracking 1,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05854667RecruitingPhase 2
High-dose lisdexamfetamine with rewards for meth use changes
This Phase 2 study tests high-dose lisdexamfetamine (a prescription stimulant) to help people reduce or stop methamphetamine use. It also uses “contingency management” (rewards tied to meeting goals) to encourage treatment participation and lower use.
Vancouver, British ColumbiaAges 18–55 - NCT05819268Recruiting
Mind and body program by telehealth for functional seizures
This trial tests whether a “retraining and control” mind-body program delivered online can help reduce symptoms of functional seizures in teens. It’s mainly a feasibility study, meaning it checks if the program can be done safely and in a way that works for families.
Birmingham, AlabamaAges 11–18 - NCT05812807RecruitingPhase 3
Pembrolizumab versus monitoring after triple-negative breast cancer response
This trial checks whether giving pembrolizumab (an immunotherapy) after surgery helps people with triple-negative breast cancer reduce the chance of the cancer coming back, compared with close monitoring only. It’s for patients who had no remaining invasive cancer after neoadjuvant chemotherapy plus pembrolizumab.
Birmingham, AlabamaAges 18 years+ - NCT05758077Recruiting
SeLective blood-filter trial for acute kidney injury in ICU
This trial tests a special device that filters parts of the blood to calm inflammation in people with severe acute kidney injury in the ICU. It may help improve recovery and reduce complications by “deactivating” certain immune cells.
Birmingham, AlabamaAges 18 years+ - NCT05768386Enrolling by invitation
Long-term follow-up for severe hemophilia A after BMN 270 study
This study checks how people with severe hemophilia A are doing over time after joining a previous BioMarin study of BMN 270. It helps researchers understand long-term safety and outcomes and may support your ongoing care plan.
Los Angeles, CaliforniaAges 18 years+ - NCT05765175Recruiting
Radioablation versus repeat ablation for hard-to-treat VT
This trial compares a heart procedure using targeted radiation (called radioablation) to a repeat catheter ablation for people with high-risk, hard-to-control ventricular tachycardia (VT). It aims to find which approach is safer and works better after standard ablation and amiodarone have not stopped the abnormal rhythm.
Los Angeles, CaliforniaAges 18 years+ - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05747729RecruitingPhase 1/Phase 2
Study of surufatinib, serplulimab, chemo for neuroendocrine carcinoma
This trial tests a combination of two targeted therapies (surufatinib and serplulimab) plus standard chemotherapy (platinum and etoposide) for people with a rare, aggressive type of cancer called neuroendocrine carcinoma that started outside the lung. The goal is to see if this new combination works better than chemotherapy alone.
Wuhan, HubeiAges 18 years+ - NCT05719441RecruitingPhase 2
Testing HIV antibodies plus early HIV treatment for possible remission
This trial tests whether giving two powerful HIV-fighting antibodies (called broadly neutralizing monoclonal antibodies) along with starting standard HIV medications soon after infection can help control the virus without needing daily pills. If successful, it might allow people to take a 'treatment pause' while keeping their immune system healthy.
Birmingham, AlabamaAges 18–70 - NCT05727787Recruiting
Radiation trial for liver cancer that cannot be removed
This Phase I study tests a specific radiation approach (vGRID SBRT) for hepatocellular carcinoma (and some mixed types) that is advanced and cannot be cured with surgery or transplant. It aims to control tumors while staying within safety limits for the liver and nearby organs.
Kansas City, KansasAges 18 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05681780RecruitingPhase 1
CD40L-treated immune cells for advanced lung cancer with certain gene changes
This Phase 1 study tests a lab-made immune cell treatment (TIL) boosted with CD40L, plus nivolumab, for stage IV or returning non-small cell lung cancer with specific gene changes (EGFR, ALK, ROS1, or HER2). It aims to help your immune system attack the cancer after it has grown despite standard treatments.
Tampa, FloridaAges 18 years+ - NCT05674799Recruiting
Program to lower future obesity and diabetes risks
This trial tests a lifestyle and coaching program (NDPP-NextGen) to help reduce the chances of obesity and diabetes risk passing to the next generation. It’s for people planning a pregnancy soon and who may be at higher risk due to body weight.
Winston-Salem, North CarolinaAges 18–39 - NCT05703256Recruiting
Brain training with feedback to help depression
This trial tests a type of brain training called amygdala neurofeedback to reduce depression symptoms. It may help by teaching your brain patterns to become less “stuck” in depression-related activity.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05677490RecruitingPhase 3
Chemotherapy with or without immunotherapy for advanced stomach or esophagus cancer
This trial compares two chemotherapy combinations, with or without an immunotherapy drug called nivolumab, for people with advanced stomach, esophagus, or gastroesophageal junction cancer that cannot be removed by surgery. The goal is to see which treatment works better and if adding immunotherapy helps.
Birmingham, AlabamaAges 18 years+ - NCT05647265RecruitingPhase 2
Immunotherapy before surgery for sarcomatoid pleural mesothelioma
This trial tests adding immunotherapy before surgery to help patients with sarcomatoid pleural mesothelioma. The goal is to shrink or control the cancer and make surgery possible, while checking safety.
Anchorage, AlaskaAges 18 years+ - NCT05655494Recruiting
Helping underrepresented people find cancer clinical trials
This study tests an approach to help people from groups historically underrepresented in cancer trials learn about and connect to clinical trials. It may help you get easier, more personal ways to be contacted about research options.
Gainesville, FloridaAges 18–100 - NCT05611801RecruitingPhase 3
Study medicine for children with hemophilia A or B
This trial tests a study medicine (marstacimab) for children with severe hemophilia A or B, to see if it can help prevent or reduce bleeding episodes. It may be an option for children who do not have certain other health conditions.
Salt Lake City, UtahAges 1–17 - NCT05603910RecruitingPhase 1
Drug and radiation combo for recurrent pelvic endometrial cancer
This study tests a combination of two drugs (lenvatinib and pembrolizumab) plus focused radiation to the pelvis for a specific type of endometrial cancer that has returned or cannot be surgically removed. The goal is to see if this treatment is safe and effective for tumors that are pMMR and limited to the pelvic area.
Miami, FloridaAges 18 years+ - NCT05635591Enrolling by invitationPhase 1
KSD-101 vaccine trial for EBV-related blood cancers
This early-phase trial studies KSD-101 (a vaccine treatment) for people whose blood cancers are linked to EBV and who have not responded or have relapsed after standard treatment. It may help your immune system better control the cancer, especially when other options have already been tried.
Wuhan, HubeiAges 18–70 - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05594368RecruitingPhase 1
Test targeted radiation to treat recurrent ventricular tachycardia
This trial studies a radiation approach (called stereotactic body radiation therapy, or SBRT) to treat ventricular tachycardia (a dangerous heart rhythm) that keeps coming back. It aims to reduce the rhythm episodes in people who have already tried catheter ablation (a procedure to cauterize rhythm sources) or cannot have it.
OstravaAges 18 years+ - NCT05608148RecruitingPhase 1
GAIA-102 for relapsed or hard-to-treat childhood cancers
This Phase 1 study tests GAIA-102 in children and young adults whose cancer has returned or not responded to standard treatments. It aims to see if the treatment is safe and whether it may shrink tumors in certain pediatric solid cancers.
Fukuoka, FukuokaAges 1–24 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age
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Common questions
- Are there clinical trials for clinical trials?
- Yes. Clin2 currently lists 1,057 recruiting clinical trials studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a clinical trials trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a clinical trials trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Clinical Stage IV Cutaneous Melanoma AJCC v8
- Clinical Competence
- Clinical High Risk for Psychosis (CHR)
- Clinical Stage III Cutaneous Melanoma AJCC v8
- Clinical Stage III Gastric Cancer AJCC v8
- Clinical Stage III Esophageal Adenocarcinoma AJCC v8
- Clinical Stage IV Gastric Cancer AJCC v8
- Clinical Decision Support
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.