Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05935241Recruiting
Program mPATH for sleep and activity in older adults
This trial tests a program (mPATH) to help older adults with sleep trouble by improving activity and exercise habits. It may be helpful if you have low income and want support building moderate exercise safely.
Baltimore, MarylandAges 65 years+ - NCT05915000Recruiting
CSF protein tests to predict shunt response in hydrocephalus
This study looks at fluid-based “CSF” protein markers to predict how well a brain shunt works in adults with chronic hydrocephalus (fluid buildup). If you qualify, your CSF sample may help doctors better estimate your likely response to treatment.
Valencia, ValenciaAges 18 years+ - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT05925621Recruiting
Registry for early Alzheimer-related memory problems
This study registry collects health and brain-testing information for people with mild cognitive impairment or early Alzheimer’s dementia. It may help researchers better understand early Alzheimer disease and plan future treatments.
Boston, MassachusettsAges 50–95 - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT05894967Recruiting
Study on how perceptual learning works in different age groups
This study looks at what helps people improve how they perceive visual information (“perceptual learning”) and what processes are responsible. It includes younger and older adults and mainly needs good vision and no known eye or brain conditions affecting the retina or nerves.
Riverside, CaliforniaAges 18–85 - NCT05880719Recruiting
Music-based computer program for memory after first psychosis
This study tests whether using a computer-based music program can help improve memory and thinking in young people who have had their first episode of psychosis. Participants will work in small groups with the program to see if it helps their cognitive skills.
CaenAges 18–30 - NCT05906407Recruiting
Genetic-guided treatment planning for high-risk early breast cancer
This study uses tumor genetic testing to help plan more precise treatment for people with early high-risk breast cancer. You may be asked to give a recent tumor sample so researchers can match your cancer features with the best available options.
AugsburgAges 18–80 - NCT05904132Recruiting
Brain stimulation therapy for early Alzheimer’s memory loss
This trial studies a “closed-loop” brain stimulation approach to improve symptoms in people with early Alzheimer’s-related memory problems. It may help by delivering stimulation based on your brain signals, if you meet the safety and diagnosis requirements.
Charlestown, MassachusettsAges 50–80 - NCT02434393Recruiting
Studying brain changes in late-life depression and memory decline
This study looks at how thinking and memory change in people with depression later in life, using brain imaging and related assessments. Your past participation and whether your treatments are stable enough around the time of the brain scan may determine whether you can join.
San Francisco, CaliforniaAges 65 years+ - NCT05858346Recruiting
Therapy for social anxiety in Veterans with trauma symptoms
This study compares two kinds of treatment for social anxiety disorder to see which one works better for Veterans. It focuses on people who also have significant posttraumatic stress symptoms (trauma-related symptoms).
Charleston, South CarolinaAges 18–80 - NCT02832193Recruiting
Uses past anesthesia test data to study memory after surgery
This study looks back at information already collected around elective surgery to understand how anesthesia and surgery may affect thinking and memory (sometimes called POCD). It mainly uses records and questionnaires rather than adding a new treatment.
BerlinAges 18–100 - NCT05492032Recruiting
Brain stimulation sessions for teens with autism symptoms
This trial tests whether repeated, brain-based stimulation (done through the scalp) can improve symptoms in adolescents with autism spectrum disorder, and whether a later “booster” session adds more benefit. It may help learn which stimulation schedule works best, especially when teens also have attention symptoms—but not epilepsy or mood/anxiety disorders.
Hung Hom, KowloonAges 12–21 - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+ - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05830903Recruiting
Virtual reality job training for people with schizophrenia
This trial tests a virtual reality (VR) training program to help people with schizophrenia prepare for work. It aims to see whether VR-based job skills training is safe and helpful for improving readiness and functioning.
TaipeiAges 20–40 - NCT05843604Recruiting
Brain and thinking tests to study OCD treatment resistance
This study looks at brain and thinking (cognitive) markers to understand why some people with obsessive-compulsive disorder (OCD) don’t respond as well to treatment. If you have OCD, you may be asked to take tests and follow the study rules to help researchers better predict treatment resistance.
PoitiersAges 18–70 - NCT05816915Recruiting
Lifestyle changes for fatty liver with metabolic health issues
This trial studies whether a lifestyle program can improve fatty liver disease in people who also have metabolic syndrome (a cluster of health problems like high blood sugar and cholesterol). It may help by improving liver health through diet, activity, and other lifestyle changes.
PragueAges 18 years+ - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05796401RecruitingPhase 3
Personalized care program for early psychosis outcomes
This trial tests whether a personalized care plan improves day-to-day functioning for people in the early stages of psychosis. It aims to see if adding structured support after a recent diagnosis can help you function better.
BrestAges 15–30 - NCT05799846Recruiting
Online strategies to help with weight loss
This study tests a cognitive (thinking-focused) approach delivered through the internet to help you lose weight. You may be eligible if you have overweight or obesity and can regularly complete online activities and visits.
Providence, Rhode IslandAges 18–70
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.