Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04061135Recruiting
Study brain and movement patterns in Parkinson’s or tremor
This study looks at brain signals, thinking, and movement behaviors in people who have Parkinson’s disease or essential tremor and are being considered for deep brain stimulation (DBS) surgery. It may help researchers better understand how DBS affects the brain and day-to-day function.
Birmingham, AlabamaAges 18 years+ - NCT04041154Recruiting
Study of how the brain senses effort cost
This study asks people to do tasks while the researchers measure brain activity, to understand how the brain represents the “cost” of effort. It may help improve understanding of effort-related problems in mental and neurological conditions.
Baltimore, MarylandAges 18–35 - NCT04042532Enrolling by invitation
Theta-burst brain stimulation for younger-onset Alzheimer’s
This trial tests whether a form of brain stimulation (theta-burst stimulation) can improve thinking and memory in people with younger-onset Alzheimer’s. It also compares results with people without dementia who meet similar age and health requirements.
Taoyuan, GuishanAges 50–75 - NCT03912194RecruitingPhase 3
Training to help you quit smoking sooner and feel better
This Phase 3 study tests a quit-training program that teaches how to handle urges and negative feelings when you start cutting back or stopping smoking. You may benefit by improving your chances of quitting and reducing stress during withdrawal.
Birmingham, AlabamaAges 18 years+ - NCT04012411Recruiting
Testing brain fluid biomarkers in Huntington’s disease
This study looks at specific “biomarkers” (measurable signs) found in cerebrospinal fluid, to better understand Huntington’s disease. The results may help researchers track the disease and improve future tests or treatments.
MontpellierAges 18 years+ - NCT03932773Recruiting
Check rTMS treatment for combat-related PTSD in veterans
This trial tests whether a non-drug brain stimulation treatment (rTMS) can reduce symptoms of PTSD in veterans who were exposed to post-9/11 combat trauma. It may help by improving PTSD symptoms, but you must meet safety rules—especially related to seizure risk.
Tallahassee, FloridaAges 18–60 - NCT03829787Recruiting
Study of attention and reward signals in bipolar disorder
This study looks at how people with bipolar disorder pay attention and respond to rewards, including whether anxiety or substance use is also present. It uses eye-tracking and related tests to better understand brain patterns that may affect mood and decision-making.
Cleveland, OhioAges 18 years+ - NCT03838536Recruiting
Breast milk nutrients and baby brain development study
This study looks at whether certain nutrients in breast milk (DHA, choline, and lutein) are linked to early thinking skills in babies. It may help researchers understand which nutrition factors could support healthy brain development.
Kannapolis, North CarolinaAges 3 months–35 years - NCT03687710Enrolling by invitation
Alzheimer’s registry for people with memory concerns or risk
This is a research registry that helps doctors compare how different memory and Alzheimer’s risk groups change over time. It may help researchers learn which people are more likely to develop Alzheimer’s and how to better track early changes.
New York, New YorkAges 18–99 - NCT03568669Recruiting
Testing thinking and learning in congenital central hypoventilation syndrome
This study looks at thinking and memory in people with congenital central hypoventilation syndrome (CCHS) to better understand how the condition affects the brain. It may help researchers measure changes over time and guide future care.
Los Angeles, CaliforniaAges 3–85 - NCT03618186Enrolling by invitationPhase 2
Brain scan study for African Americans age 30+
This Phase 2 study uses brain imaging (including PET and MRI) to learn more about brain changes. It may help researchers improve how brain patterns are measured and understood, which could guide future care.
Jacksonville, FloridaAges 30 years+ - NCT03546387Recruiting
Anesthesia and brain thinking changes in children with retinoblastoma
This study looks at whether having anesthesia more than once (for eye/surgery treatment) affects children’s thinking and learning. It may help doctors plan safer care and better follow-up for children with retinoblastoma.
New York, New YorkAges 6–17 - NCT03541135Enrolling by invitation
Study of heart health, diet, and activity in older adults
This study looks at heart health, food, and physical functioning in people age 65 and older living in Madrid. It may help researchers understand how lifestyle affects aging and cardiovascular wellbeing.
MadridAges 65–95 - NCT03574207Recruiting
Brain stimulation study for memory in certain adults
This study tests a targeted, non-surgical brain stimulation method to help people with memory, especially remembering facts over time. It compares healthy adults and adults with amnestic mild cognitive impairment (aMCI), using sessions plus brain scans and memory testing.
Omaha, NebraskaAges 19 years+ - NCT03407066Recruiting
Study of how people see, hear, think, and move
This study measures how the brain processes sight and other senses through tests done in a lab, online, or by off-site/genetic screening. It may help researchers understand normal perception and cognition, which can guide future treatments.
Bethesda, MarylandAges 13–65 - NCT03370224Enrolling by invitation
Story memory training for older adults
This study tests a memory-skills training approach (the Modified Story Memory Technique) to help older adults with aging-related memory changes. You may be asked to do memory exercises, and some people may also complete an optional brain MRI scan.
East Hanover, New JerseyAges 65 years+ - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT03217110Recruiting
Brain stimulation study for thinking and control
This trial tests whether stimulating the cerebellum (a part of the brain involved in coordination and learning) can improve “cognitive control,” or the ability to focus and manage thoughts. You may be able to join if you have a diagnosis they are specifically enrolling for and you can safely complete the stimulation and study procedures.
Iowa City, IowaAges 18–90 - NCT03089827Enrolling by invitation
Tests how a brain imaging tracer spreads in Alzheimer’s risk
This trial uses a radioactive imaging tracer to see how it moves and settles in the brain in people with risk factors for Alzheimer’s disease. It may help researchers understand which people show tracer patterns linked to Alzheimer’s changes.
Winston-Salem, North CarolinaAges 55 years+ - NCT03101722Enrolling by invitation
Huperzine A for hearing loss, tinnitus, and mild memory issues
This trial tests whether huperzine A can improve hearing-related symptoms along with tinnitus (ringing) and mild cognitive (memory/thinking) problems. If you have mild-to-moderate hearing loss plus bothersome constant tinnitus and some cognitive decline, this study may help researchers see if the treatment makes a difference.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT03184038Recruiting
Testing brain function in people with brain metastases after radiosurgery
This study looks at how well your thinking and memory work after treatment with radiosurgery for brain metastases. It may help researchers understand which patients benefit best and how to monitor side effects on brain function.
Sewell, New JerseyAges 18 years+ - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02972008Recruiting
Looking for blood markers that predict complications after TAVI
This study enrolls older adults having a minimally invasive heart valve procedure (TAVI) to find “epigenetic” risk markers—signals in the body that may predict who is more likely to have complications during the procedure. If you qualify, your blood and/or samples may be studied to improve safety for future patients.
LilleAges 70 years+
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.