Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05877196Recruiting
Adaptive walking and fitness program for mild memory decline
This study tests an “adaptive” exercise plan that adjusts over time to help improve aerobic fitness and your body’s fitness response in people with mild memory problems or early Alzheimer’s. It may help you safely build the kind of fitness that supports brain health, while researchers monitor changes with fitness testing and blood work.
Phoenix, ArizonaAges 65 years+ - NCT05948930Recruiting
Exercise and brain training for mild memory problems
This study tests whether a mix of physical exercise and computer brain training can improve working memory in people with mild cognitive impairment (MCI). It may help by strengthening memory skills and supporting brain health through supervised activity and computer-based practice.
Baltimore, MarylandAges 50–80 - NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06058611Recruiting
Computer brain training vs. fun activities for memory
This study compares two types of brain activities: a computer-based cognitive training program and engaging leisure activities like puzzles or games. The goal is to see which approach better helps memory and thinking skills in older adults with mild cognitive concerns.
Zaragoza, ZaragozaAges 50 years+ - NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT06150352Recruiting
Sleep apnea and memory in older adults with mild concerns
This trial looks at how sleep apnea affects memory and brain health in people who have mild memory problems or are worried about their memory. You will have a sleep study and brain scans to see if treating sleep apnea could help protect your thinking skills.
Hong KongAges 50–80 - NCT06321588Recruiting
Autoimmune dementia: predicting antibodies in new cognitive decline
This study looks for certain antibodies that might be causing your new memory or thinking problems. It aims to find patterns that could help diagnose autoimmune dementia earlier.
Bologna, BolognaAges 40–90 - NCT06330844Recruiting
Stress & memory support for Black and Hispanic older adults
This research study tests a new program that combines help for stress caused by racism with memory training for people with mild cognitive impairment. It may help Black and Hispanic/Latine older adults find ways to cope and improve thinking skills.
Chicago, IllinoisAges 65 years+ - NCT06453746Recruiting
Non-drug program to prevent dementia for mild cognitive impairment
This study tests whether non-drug activities (like exercise, brain games, or lifestyle changes) can help prevent dementia in older adults with mild memory loss. You will take part in a program at the hospital and have regular checkups.
Ho Chi Minh CityAges 60 years+ - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85 - NCT06598163Recruiting
Cognitive training app for mild memory problems
This trial tests a mobile app called Five Lives MED to see if it can improve thinking and memory in people with mild cognitive impairment (MCI). You can join if you have MCI and are 50 or older.
Paris, Île-de-France RegionAges 50 years+ - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06687161Recruiting
Treating insomnia in mild memory problems
This study tests whether a non-invasive brain stimulation method (TMS) combined with cognitive training can improve sleep in older adults with mild memory issues. It may help if you have trouble falling or staying asleep and have early memory changes.
Boston, MassachusettsAges 60 years+ - NCT06828926Recruiting
Tai Chi study for older adults with memory concerns
This study tests whether tai chi can improve thinking, memory, and overall well-being in older adults who have mild memory problems (Mild Cognitive Impairment) or are healthy. It looks at how tai chi affects the brain and daily life.
Athens, OhioAges 60 years+ - NCT06867692Recruiting
Aerobic exercise for kids with mild cognitive impairment
This trial tests if aerobic exercise helps kids with mild cognitive impairment do better at two tasks at once and improve their motor skills. It could help your child think and move more easily.
Lahore, Punjab ProvinceAges 7–12 - NCT06927362Recruiting
Exercise and balance training for seniors with memory issues
This study tests if combining two types of exercise (LSVT Big and dual-task training) can improve balance and thinking in older adults with mild to moderate memory loss. It may help you stay steady on your feet and manage everyday tasks more easily.
Lahore, Punjab ProvinceAges 65 years+ - NCT07125170Recruiting
Virtual reality for thinking skills after stroke
This trial tests whether immersive virtual reality can help improve thinking and memory problems after a recent stroke. It is designed for people who have mild to moderate cognitive issues and are already scheduled for occupational therapy.
Independencia, Santiago MetropolitanAges 18 years+ - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT07286448Recruiting
Digital Brain Training for Mild Memory Problems
This trial tests a personalized digital brain training program for people with mild memory or thinking problems. It aims to see if the training can boost cognitive fitness and help maintain your thinking skills.
Modena, Reggio Nell'Emilia (RE)Ages 50 years+ - NCT07334392Recruiting
Exercise program for mild memory problems
This trial tests if a supervised exercise program can improve thinking skills and daily function in people with mild cognitive impairment (MCI). It may help slow memory decline and keep you independent longer.
PátraiAges 50 years+ - NCT07364019Recruiting
Brain Health PRO: Online program to reduce dementia risk
This study tests an online program designed to lower your risk of developing dementia. It provides education and support to help you make brain-healthy changes.
Vancouver, British ColumbiaAges 50–80 - NCT07366346Recruiting
Telehealth memory training for older adults with mild memory concerns
This study tests a telehealth program to help older adults with mild memory problems improve their thinking skills and daily life. It involves working with a study partner, like a family member or friend.
Gainesville, FloridaAges 65–84 - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 577 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.