Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05771844Recruiting
Home sleep treatment for older adults with memory changes
This study tests whether a home sleep therapy program can improve symptoms in older adults who have amnestic mild cognitive impairment (MCI) or help compare to people without MCI. It may be useful if your main issue is memory or thinking changes and you also have sleep problems.
Winston-Salem, North CarolinaAges 40–85 - NCT06832839Recruiting
Cognitive impairment in moyamoya disease study
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
Beijing, ChinaAges 18–60 - NCT06850597RecruitingPhase 2
Testing dimethyl fumarate for early Alzheimer's disease
This study tests a drug called dimethyl fumarate to see if it can help people with early Alzheimer's disease. It may slow down memory loss and thinking problems.
Lodz, Łódź VoivodeshipAges 55–90 - NCT07342075Recruiting
Registry Study of Small Vessel Disease in the Brain
This study tracks people with cerebral small vessel disease (changes in the brain's tiny blood vessels) to learn more about how the condition progresses. It may be a good fit if you are 50 or older and have had an MRI showing these changes.
Beijing, Beijing MunicipalityAges 50 years+ - NCT06863727Recruiting
Beijing disability survey in older adults
This study is a survey that follows older adults in Beijing over time to track disability. It aims to understand how disabilities develop in the community, which could help improve care for older people.
BeijingAges 65 years+ - NCT07314892Recruiting
Psychiatric health and symptom severity in GvHD patients
This study looks at how graft-versus-host disease (a complication after a bone marrow transplant) affects mental health and symptom severity. It aims to understand the connection so that doctors can better support patients.
Gdansk, Pomeranian VoivodeshipAges 18–75 - NCT06541834Recruiting
Predicting diabetes eye nerve problems with retina scans
This study uses artificial intelligence to analyze retinal images and predict the risk of nerve-related problems caused by diabetes. It may help identify those at risk before symptoms appear.
MilanAges 45 years+ - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT05980117RecruitingPhase 4
Remimazolam sedation for cataract surgery
This study tests a sedative, remimazolam, for older adults having their first cataract surgery. It aims to see if it helps keep patients comfortable and calm without needing general anesthesia.
Los Angeles, CaliforniaAges 65 years+ - NCT06619613RecruitingPhase 1
Study of CM383 for early Alzheimer's disease
This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.
HefeiAges 50–85 - NCT07272811Recruiting
Computer memory testing for early Alzheimer's signs
This study uses a computer-based platform to test memory and thinking in healthy adults and in people with mild memory concerns (called aMCI). The goal is to better understand how memory changes with age and to spot early signs of Alzheimer's disease.
Milan, ItalyAges 55–80 - NCT06068361Recruiting
Better diagnosis of Lewy body dementia
This study uses a combination of tests to improve diagnosis of dementia with Lewy bodies compared to Alzheimer's disease and healthy aging. You may help doctors identify the right diagnosis more accurately.
Paris, FranceAges 55–85 - NCT05708807Recruiting
Follow-up study of recovery after first-time stroke in Gothenburg
This study tracks how people recover after their first-ever stroke (either blocked artery stroke or bleeding in the brain). It may help doctors better understand recovery patterns and what support could work best over time.
GothenburgAges 18 years+ - NCT07237009Recruiting
Personalized reminiscence therapy for memory loss
This trial tests a digital app that uses personal photos and memories to help people with early memory problems feel less depressed or apathetic. It's designed for seniors who have mild cognitive impairment or early dementia.
AngersAges 60 years+ - NCT07234357Recruiting
Scent therapy for mood and behavior in early dementia
This trial uses pleasant scents (aromatherapy) to see if they can improve mood and behavior for people with early memory loss. It is designed for individuals who have a caregiver who can help them participate.
SingaporeAges 50–99 - NCT07238049Enrolling by invitation
Real-world dementia outcomes: an observational study
This study follows people with memory or thinking problems over time to learn more about how these conditions progress. It's an observational study, meaning no new treatments are tested—just information is collected from your regular care.
BangorAges 45 years+ - NCT07226219RecruitingPhase 1
Medication to help attention in children with sickle cell disease
This study tests whether a common medication called methylphenidate (often used for ADHD) can help children with sickle cell disease who have attention or memory problems. If the child qualifies, the study may offer a new way to improve focus and daily functioning.
Memphis, TennesseeAges 8–17 - NCT06912321Recruiting
Brain Circuit Study for Type 2 Diabetes
This study uses MRI scans to look at a specific brain circuit (the Papez loop) in people with type 2 diabetes. It aims to understand how diabetes might affect brain networks related to memory and emotion.
Nanjing, JiangsuAges 45–70 - NCT07220538RecruitingPhase 4
Ginkgo biloba for memory problems after a mild stroke
This trial tests whether adding ginkgo biloba extract tablets to standard stroke care helps improve memory and thinking in people who had a mild stroke. You may join if you are 55 or older, had a mild stroke in the last 1 to 2 weeks, and now have some cognitive difficulties.
AnyangAges 55 years+ - NCT07220668RecruitingPhase 1/Phase 2
Safety check for older adults in senior living
This trial tests a new program called Sense4Safety to help prevent falls and keep seniors living independently. It uses a simple physical test and a memory screening to see if you're eligible.
Philadelphia, PennsylvaniaAges 65 years+ - NCT06207942Recruiting
Extended follow-up for cardiac arrest survivors and caregivers
This study follows up on survivors of out-of-hospital cardiac arrest who were already in the STEPCARE trial. It also looks at the well-being of their main caregiver (like a family member or close friend) to see how everyone is doing over time.
BrisbaneAges 18 years+ - NCT07166224Recruiting
Home treatments for gum disease in older adults with memory issues
This trial tests two simple ways to improve gum health at home: using a special light-activated antibacterial rinse or using a powered toothbrush. It's for older adults who have gum disease and mild memory problems, and aims to see if these easy routines can help keep gums healthier.
Karlskrona, Blekinge CountyAges 60 years+ - NCT07162467Enrolling by invitation
Exploring metabolism and thinking in schizophrenia
This trial looks at how a natural chemical pathway in the body might relate to thinking problems in people with schizophrenia. It compares healthy volunteers to people with schizophrenia to find biological clues.
TianjinAges 18–55 - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 571 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.