Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06058234Recruiting
Tracking Alzheimer’s treatment for Medicare patients in early stages
This study tracks how well a certain type of Alzheimer’s treatment works for people on Medicare who are in the early stages of the disease. The goal is to collect real-world information about the drug’s benefits and risks.
Baltimore, MarylandAges Any age - NCT06068361Recruiting
Better diagnosis of Lewy body dementia
This study uses a combination of tests to improve diagnosis of dementia with Lewy bodies compared to Alzheimer's disease and healthy aging. You may help doctors identify the right diagnosis more accurately.
Paris, FranceAges 55–85 - NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90 - NCT06079411Recruiting
Virtual reality therapy for mild cognitive impairment in older adults
This study tests a virtual reality program to help improve memory and thinking in people with mild cognitive impairment (MCI). It is for adults aged 65 and over who have noticed changes in their cognition but do not have dementia.
Milan, LombardyAges 65 years+ - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06112860Recruiting
Over-the-counter hearing aids for memory loss study
This trial tests whether over-the-counter hearing aids can help people with mild memory loss (mild cognitive impairment or mild dementia) who also have hearing loss. You and a communication partner will participate together to see if improving hearing can also help with thinking and communication.
Evanston, IllinoisAges 60–90 - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80 - NCT06122415Recruiting
Memory clinic study with fluid and cognitive tests
This study looks at people who are being checked for memory or thinking problems. It uses standard tests done at the memory clinic, like a spinal tap and blood draw, plus memory and thinking tests, to learn more about these symptoms. You can join if these tests are already planned as part of your regular care, even if you don't take part in the study.
MalmöAges Any age - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06191965RecruitingPhase 2/Phase 3
MitoQ supplement for early psychosis
This study tests whether a supplement called MitoQ can help people with early-stage psychosis by improving how their cells produce energy. If you are younger and have been treated for psychosis for less than 5 years, this trial may be an option for you.
New Haven, ConnecticutAges 18–35 - NCT06207942Recruiting
Extended follow-up for cardiac arrest survivors and caregivers
This study follows up on survivors of out-of-hospital cardiac arrest who were already in the STEPCARE trial. It also looks at the well-being of their main caregiver (like a family member or close friend) to see how everyone is doing over time.
BrisbaneAges 18 years+ - NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06307574Recruiting
Smartphone study to help older adults manage blood pressure medication
This study tests a digital tool called bpMedManage to help adults aged 60 and older remember and manage their blood pressure medications. It's for people who have some memory or thinking challenges and use a smartphone.
Tucson, ArizonaAges 60 years+ - NCT06337201Recruiting
Digital life stories for dementia care
This trial tests a digital tool to create life stories for older adults with dementia. It aims to help healthcare workers provide more personalized care.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06342661Recruiting
VISTA protein in blood vessel-related memory problems
This study measures levels of a protein called VISTA in the blood of people with memory problems caused by blood vessel disease. It aims to see if VISTA can help diagnose or predict this condition.
Harbin, HeilongjiangAges 50–80 - NCT06363981Recruiting
Brain stimulation for depression, sleep and memory problems
This study tests a non-invasive brain stimulation treatment (called rTMS) to help with depression, sleep problems, and memory or concentration issues. It's designed for people with moderate to severe depression who also have trouble sleeping and thinking clearly.
KrakowAges 18–65 - NCT06385951Recruiting
Virtual reality navigation test for early Alzheimer's detection
This study uses a virtual reality navigation task to detect early signs of Alzheimer's disease. It compares people with mild cognitive problems, mild Alzheimer's, and healthy older adults to see if this test can spot the disease earlier.
Ghent, East-FlandersAges 50–80 - NCT06395558Recruiting
Online support program for cardiac arrest survivors
This trial tests if an internet-based program helps people recover after a cardiac arrest. You may qualify if you were discharged from the hospital with good brain function and can use the web.
Bologna, BolognaAges 18–80 - NCT06417086Recruiting
Acupuncture for Alzheimer's in gene carriers and non-carriers
This trial tests whether acupuncture can help people with Alzheimer's disease. Researchers will compare results in people who carry the APOE e4 gene and those who don't, to see if the treatment works differently.
ShanghaiAges 50–80 - NCT06427265Recruiting
Recovery after ICU: a long-term study
This study follows people after they leave the ICU to see how they recover over time. It uses computer programs to find patterns and create early warning tools to help doctors spot problems sooner.
Guiyang, GuizhouAges 18–100 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.