Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07395960RecruitingPhase 1/Phase 2
Metformin for older adults with mild memory loss and higher weight
This trial tests if metformin can help older adults (60-75) who are overweight and have mild memory problems. It aims to see if the drug can slow down or improve memory issues.
ShanghaiAges 60–75 - NCT07332624Enrolling by invitation
Therapy via text for mild memory problems and mood changes
This study tests if acceptance and commitment therapy (ACT) delivered through instant messaging can help older adults with mild memory issues manage emotional or behavioral symptoms like anxiety, depression, or agitation.
Hong KongAges 50 years+ - NCT07296133Recruiting
GAMES brain training for mild cognitive impairment
This study tests whether a computer-based program called GAMES can help people with mild cognitive impairment (MCI) improve their thinking and memory skills.
Atlanta, GeorgiaAges 50–85 - NCT07242495Recruiting
Virtual reality with exercise for memory in older adults
This trial tests whether using 360-degree virtual reality videos during aerobic exercise can improve thinking and memory in older adults with mild cognitive impairment. It's a chance to try a new approach that combines exercise and immersive technology.
IslamabadAges 60 years+ - NCT07225400Recruiting
Brain training for navigation in mild memory loss
This trial tests a new way to help people with mild memory problems improve their sense of direction and navigation. You will be asked to do tasks while wearing a special cap that records brain activity, to see how your brain responds to spatial challenges.
Manhattan, New YorkAges 65 years+ - NCT06902181Recruiting
Inhaling an essential oil for mild memory loss
This trial tests whether inhaling a special essential oil (CXMCI-01) can help people with mild cognitive impairment (MCI) — a condition where you have more memory problems than normal for your age. The study aims to see if the oil is safe and might improve memory and thinking.
TaichungAges 50 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT06951932Recruiting
Do fatty acids help early memory loss?
This study tests whether a special oil (medium-chain fatty acids) can help people who were recently diagnosed with mild cognitive impairment. If you join, you'll take the oil and be checked to see if it slows down memory decline.
Alessandria, PiedmontAges 18–85 - NCT07142499Recruiting
Memory support program for older Chinese Americans with mild memory loss
This trial tests a memory support system designed for older Chinese Americans who speak Cantonese or Mandarin and have mild cognitive impairment (MCI), a slight decline in memory and thinking skills. It aims to help participants and their study partners manage daily memory challenges.
New York, New YorkAges 55 years+ - NCT07135336Recruiting
Cognitive decline after surgery in older adults with memory problems
This study looks at how surgery and anesthesia affect memory and thinking in older adults who already have mild memory problems. It compares patients having elective non-cardiac surgery with a similar group who are not having surgery, to see if the surgery itself causes more confusion or memory decline.
Shenzhen, GuangdongAges 60 years+ - NCT06974890Recruiting
Balance training for children with mild cognitive impairment
This study tests if special balance exercises can help improve walking, balance, and posture control in children with mild cognitive impairment. It may help your child move more confidently and safely.
Lahore, Punjab ProvinceAges 6–12 - NCT06825403Recruiting
Olfactory training for mild cognitive impairment
This trial tests whether daily scent training can help improve memory and thinking in people with mild cognitive impairment (MCI), a condition that is more than normal aging but not dementia. You would smell different odors at home and track your progress.
New York, New YorkAges 55–89 - NCT05708001Recruiting
Testing brain stimulation to improve memory in mild impairment
This study tests whether a noninvasive brain stimulation method (tACS) can improve memory in people with mild cognitive impairment (MCI). A caregiver also helps with the stimulation during the study, and success is measured through study visits and memory-related evaluations.
GenevaAges 55–85 - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06670807Recruiting
Probiotic supplement for mild memory loss
This study tests whether a probiotic (a supplement with helpful bacteria) can help slow down memory and thinking problems in people with mild cognitive impairment (MCI). It is for adults aged 60–85 who have noticed their memory getting worse over time but can still handle daily activities.
Madrid, MadridAges 65–85 - NCT06466460Recruiting
Interactive bike for quality of life in memory loss
This study tests if using a special interactive stationary bike can improve quality of life for older adults with memory or thinking problems who live in nursing homes. You would be asked to pedal the bike a few times, and the program makes it fun and engaging.
ÖrebroAges 65 years+ - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT05858008Recruiting
Time-restricted eating program for women with mild memory loss
This trial tests whether a structured “time-restricted eating” schedule is practical and safe for women with mild cognitive impairment (mild memory/thinking changes). You may be able to join if your routine and health conditions fit the study rules, and they will focus on eating timing and daily patterns.
Lexington, KentuckyAges 45–95 - NCT05725668Recruiting
Dual-task exercise to help prevent falls in memory trouble
This study tests a type of exercise training (doing a physical task while also doing a thinking task) to help older adults with mild memory problems prevent falls. If you have fallen before or have trouble with balance, this program may help you improve safety and coordination.
Springfield, OregonAges 65–95 - NCT05396248Recruiting
Memory training study for older adults with mild memory problems
This trial tests an approach to improve learning and memory in people age 60+ with amnestic mild cognitive impairment (a specific type of early memory problem). It may help by supporting memory and learning skills, but it also has medication and health-history requirements.
Ann Arbor, MichiganAges 60 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Phoenix, ArizonaAges 18 years+ - NCT06279325Recruiting
Computer brain training for older adults
This trial studies whether a computer-based brain training program can help thinking skills in older adults. It is designed for people who are generally healthy and have not received similar training before.
Zaragoza, ZaragozaAges 60 years+ - NCT07504276Recruiting
Remote rehab vs in-person rehab for stroke recovery
This study compares doing brain-training exercises at home on a digital device versus going to a clinic after a stroke. It aims to see which method better helps improve memory, thinking, and daily function.
Islamabad, Punjab ProvinceAges 50–80 - NCT03360838Recruiting
Prediction test for confusion after heart surgery in older adults
This study uses a short, self-answered thinking test before elective heart surgery to help predict who may develop confusion afterward. The goal is to improve early identification and care planning for patients at higher risk.
BaselAges 60 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 571 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.