Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06825403Recruiting
Olfactory training for mild cognitive impairment
This trial tests whether daily scent training can help improve memory and thinking in people with mild cognitive impairment (MCI), a condition that is more than normal aging but not dementia. You would smell different odors at home and track your progress.
New York, New YorkAges 55–89 - NCT06902181Recruiting
Inhaling an essential oil for mild memory loss
This trial tests whether inhaling a special essential oil (CXMCI-01) can help people with mild cognitive impairment (MCI) — a condition where you have more memory problems than normal for your age. The study aims to see if the oil is safe and might improve memory and thinking.
TaichungAges 50 years+ - NCT06951932Recruiting
Do fatty acids help early memory loss?
This study tests whether a special oil (medium-chain fatty acids) can help people who were recently diagnosed with mild cognitive impairment. If you join, you'll take the oil and be checked to see if it slows down memory decline.
Alessandria, PiedmontAges 18–85 - NCT06974890Recruiting
Balance training for children with mild cognitive impairment
This study tests if special balance exercises can help improve walking, balance, and posture control in children with mild cognitive impairment. It may help your child move more confidently and safely.
Lahore, Punjab ProvinceAges 6–12 - NCT07097051RecruitingPhase 2
Brain stimulation to help older adults with mild memory problems stand and walk better
This study tests if a gentle electrical current applied to the scalp (called transcranial alternating current stimulation, or tACS) can improve your ability to stand and walk while doing another task. It aims to help older adults with mild memory problems become more stable and reduce fall risk.
High Point, North CarolinaAges 65–85 - NCT07135336Recruiting
Cognitive decline after surgery in older adults with memory problems
This study looks at how surgery and anesthesia affect memory and thinking in older adults who already have mild memory problems. It compares patients having elective non-cardiac surgery with a similar group who are not having surgery, to see if the surgery itself causes more confusion or memory decline.
Shenzhen, GuangdongAges 60 years+ - NCT07142499Recruiting
Memory support program for older Chinese Americans with mild memory loss
This trial tests a memory support system designed for older Chinese Americans who speak Cantonese or Mandarin and have mild cognitive impairment (MCI), a slight decline in memory and thinking skills. It aims to help participants and their study partners manage daily memory challenges.
New York, New YorkAges 55 years+ - NCT07242495Recruiting
Virtual reality with exercise for memory in older adults
This trial tests whether using 360-degree virtual reality videos during aerobic exercise can improve thinking and memory in older adults with mild cognitive impairment. It's a chance to try a new approach that combines exercise and immersive technology.
IslamabadAges 60 years+ - NCT07296133Recruiting
GAMES brain training for mild cognitive impairment
This study tests whether a computer-based program called GAMES can help people with mild cognitive impairment (MCI) improve their thinking and memory skills.
Atlanta, GeorgiaAges 50–85 - NCT07395960RecruitingPhase 1/Phase 2
Metformin for older adults with mild memory loss and higher weight
This trial tests if metformin can help older adults (60-75) who are overweight and have mild memory problems. It aims to see if the drug can slow down or improve memory issues.
ShanghaiAges 60–75 - NCT07420426Recruiting
Smartphone therapy for memory and mood problems
This trial tests a therapy program delivered by text or voice message on your smartphone. It's designed to help people with mild memory problems manage mood or behavior changes.
Hong KongAges 50 years+ - NCT07512739Recruiting
Sitting Tai Chi for Stroke Survivors With Cognitive Changes
This study tests whether a sitting tai chi program can help people who've had a stroke and are experiencing memory or thinking problems. You would learn tai chi movements while sitting, with your caregiver also participating in the program.
Kunming, YunnanAges 18 years+ - NCT07570719Recruiting
Community screening for early Alzheimer's disease signs
This study screens people aged 60–80 for early signs of Alzheimer's disease in a community setting. Researchers will ask you questions and may perform brain imaging to understand who might benefit from early detection and treatment.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07578896Recruiting
Balance Board Training for Children with Cognitive and Motor Delays
This study tests whether practicing on a special wobbling balance board can help improve how children with cognitive delays move and coordinate their bodies. The goal is to see if this type of training strengthens balance, coordination, and motor skills.
Lahore, Punjab ProvinceAges 6–10 - NCT07651787Recruiting
Light Therapy for Early Memory Problems
This study tests whether light therapy can help improve thinking and memory in older adults with mild cognitive changes. Researchers will use light exposure to see if it supports brain health in people with signs of blood vessel disease in the brain.
Oklahoma City, OklahomaAges 55–95 - NCT07644156Enrolling by invitation
Exercise and Memory in Older Adults with Mild Cognitive Decline
This study tests whether regular physical exercise can improve memory and thinking skills in people 65 and older who have mild cognitive impairment. Researchers want to see if staying active helps protect brain function.
Shanghai, Shanghai MunicipalityAges 65–95 - NCT07332624Enrolling by invitation
Therapy via text for mild memory problems and mood changes
This study tests if acceptance and commitment therapy (ACT) delivered through instant messaging can help older adults with mild memory issues manage emotional or behavioral symptoms like anxiety, depression, or agitation.
Hong KongAges 50 years+ - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT03360838Recruiting
Prediction test for confusion after heart surgery in older adults
This study uses a short, self-answered thinking test before elective heart surgery to help predict who may develop confusion afterward. The goal is to improve early identification and care planning for patients at higher risk.
BaselAges 60 years+ - NCT06279325Recruiting
Computer brain training for older adults
This trial studies whether a computer-based brain training program can help thinking skills in older adults. It is designed for people who are generally healthy and have not received similar training before.
Zaragoza, ZaragozaAges 60 years+ - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT07504276Recruiting
Remote rehab vs in-person rehab for stroke recovery
This study compares doing brain-training exercises at home on a digital device versus going to a clinic after a stroke. It aims to see which method better helps improve memory, thinking, and daily function.
Islamabad, Punjab ProvinceAges 50–80
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.