Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220798Recruiting
A program to support caregivers of people with heart failure and memory problems
This study tests a program to help caregivers of people with heart failure and memory problems take better care of themselves, so they can feel better and support their loved one more effectively.
New York, New YorkAges 18–101 - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT04765137RecruitingPhase 2
Atorvastatin to improve brain blood flow in mild memory decline
This Phase 2 study tests whether the cholesterol medicine atorvastatin can improve how well blood vessels in the brain respond in people with mild cognitive impairment (MCI). It may help brain circulation and possibly slow thinking and memory problems.
Baltimore, MarylandAges 60–95 - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT06516588RecruitingPhase 2
Brain stimulation for memory and thinking after stroke
This trial tests if a gentle brain stimulation technique called tDCS can help improve memory and thinking in people who have had a stroke. It is for those who are still in the early recovery phase (between 10 days and 5 months after their stroke) and have some ongoing cognitive problems.
Oklahoma City, OklahomaAges 18–99 - NCT06618807Recruiting
Infrared light for memory loss in mild cognitive impairment
This study tests whether shining a gentle infrared light on the head can help people with mild memory loss (MCI) improve their thinking and memory. It is designed for those who have mild cognitive impairment due to early Alzheimer's disease.
Toronto, OntarioAges 50 years+ - NCT07105800Recruiting
Dance classes for thinking and movement in older adults
This study tests whether weekly dance classes can help improve thinking skills (like planning and focus) and physical abilities in older adults who have noticed some memory or mood changes. You would take part in a group dance program, and the researchers will track your progress over time.
New Taipei City, TaiwanAges 55 years+ - NCT07182396Recruiting
Video games vs ball tossing for hand-eye coordination in older adults
This study tests whether playing video games or tossing balls can improve hand-eye coordination in older adults with mild memory problems. It is designed for people 60 and older who have mild cognitive impairment but are otherwise independent.
IslamabadAges 60 years+ - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT07643363Recruiting
Brain Stimulation for Cognitive Impairment in Dementia
This study tests a new brain stimulation technique called temporal interference stimulation to help slow cognitive decline in people with Alzheimer's disease or frontotemporal dementia. Researchers will combine this stimulation with cognitive training to see if it improves memory and thinking skills.
Tianjin, Tianjin MunicipalityAges 45–85 - NCT07546877Recruiting
Brain Stimulation to Improve Memory After Stroke
This study tests whether a non-invasive brain stimulation technique called high-frequency repetitive transcranial magnetic stimulation (rTMS) can help improve thinking and memory problems that occur after a stroke. If you've had a stroke in the past year and are experiencing cognitive difficulties, this trial may help restore some of your mental abilities.
JinanAges 35–75 - NCT07650318Recruiting
VR Cognitive Training for Type 2 Diabetes and Memory Problems
This study tests whether virtual-reality brain-training games can help people with type 2 diabetes who are experiencing early memory and thinking problems. Researchers will compare how cognition changes in people using VR training versus standard care over several months.
Nanjing, JiangsuAges 45–80 - NCT05831839Enrolling by invitation
Computer training for attention and memory after COVID
This study tests whether computer-based exercises can improve attention and working memory in adults who still have cognitive (thinking) complaints after COVID. It may help if your focus and memory issues have lasted for a while.
Rotterdam, South HollandAges 18 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT06948149Recruiting
Creatine and strength training for memory decline in older adults
This study tests whether combining a daily creatine supplement with a 26-week resistance training program can improve memory and thinking in older adults who have mild cognitive impairment. If you qualify, you'll get free supervision and supplements while contributing to research that could help many people.
London, OntarioAges 60 years+ - NCT07691918Enrolling by invitation
Brain stimulation for mild memory loss
This trial tests if a non-invasive brain stimulation technique can help people with mild memory problems. It uses a special cap to gently stimulate the brain and aims to improve thinking and memory.
Roanoke, VirginiaAges 55–80 - NCT06704334RecruitingPhase 4
Ginkgo and Huperzine with electrical stimulation for brain injury cognitive problems
This study tests whether a combination of Ginkgo Leaf Dropping Pills, Huperzine A injection, and median nerve electrical stimulation can improve cognitive function in people who have thinking or memory problems after a brain injury. The trial aims to see if this treatment is safe and effective compared to standard care.
Ganzhou, JiangxiAges 18–80 - NCT05195398Recruiting
Brain stimulation to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment can improve thinking and memory problems after an acute ischemic stroke. It also uses brain scans to better understand how the treatment may help.
Baltimore, MarylandAges 18–100 - NCT07446478Recruiting
TIS for improving thinking problems in schizophrenia
This trial tests if a brain stimulation technique called transcranial electrical stimulation (TIS) can help improve cognitive problems (like memory and attention) in people with schizophrenia. You may join if you are between 18 and 50, have had schizophrenia for no more than 8 years, take 1-2 antipsychotic medicines, and have some trouble with daily activities.
Changsha, HunanAges 18–50 - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT04658290Recruiting
Sleep apnea screening and memory test study
This study looks at how common obstructive sleep apnea is and whether it’s linked to thinking and memory problems. It may help clarify which people with sleep apnea might be more likely to have cognitive difficulties.
Hong Kong, Please SelectAges 40–74 - NCT05144516Recruiting
Video support program for cancer and mild memory problems
This study tests a video-based, “dyad” (patient plus family caregiver) coaching program for people with cancer and mild memory trouble (mild cognitive impairment). It may help by improving coping and communication during cancer care.
Durham, North CarolinaAges 18–100
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.