Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT05688618Recruiting
Probiotic and fiber supplement for mild memory problems
This trial studies whether a daily supplement containing a probiotic and a fiber called inulin can improve mild cognitive impairment (mild memory/thinking difficulties) in older adults. If you have mild cognitive impairment (not dementia), you may be asked to take the supplement and be monitored over time.
Mexico CityAges 70–85 - NCT06185010Recruiting
Resistance training for mild cognitive impairment
This study tests whether resistance training (exercises using weights or bands) can help people with mild cognitive impairment improve their thinking and memory. It's for those who are able to walk a bit and are ready to take part in supervised sessions.
CovilhaAges 50 years+ - NCT06347315Recruiting
Studying a nutritional drink for mild memory loss in older adults
This study tests whether a special drink containing medium-chain triglycerides (MCTs, a type of fat) and B vitamins can help support memory and thinking in older adults with mild cognitive impairment (MCI). You would take the drink daily for 18 months and have regular check-ins including memory tests.
BronAges 60 years+ - NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT06673602RecruitingPhase 4
Herbal capsule for memory problems after bleeding stroke
This trial tests a Chinese herbal capsule called Fufang Congrong Yizhi Capsule (FCYC) to see if it can help with memory and thinking problems that start after a bleeding stroke. It is for people who have had robot-assisted surgery for their stroke and also fit a specific pattern in traditional Chinese medicine.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06799429Recruiting
Exercise program for people with memory challenges
This trial tests whether a structured exercise program can help people with mild to moderate memory or thinking problems. You'll work with a trainer to improve your fitness and brain health.
Columbia, South CarolinaAges 18 years+ - NCT07149038Recruiting
Ear stimulation device study for vascular dementia
This trial tests a device that stimulates a nerve in your ear to help with memory and thinking problems caused by small blood vessel damage in the brain. It's for people with vascular dementia or a milder form called vascular mild cognitive impairment.
Hwaseong-si, Gyeonggi-doAges 55–89 - NCT07191483RecruitingPhase 2
Study of KYN-5356 for cognitive problems in schizophrenia
This trial tests an investigational drug, KYN-5356, to see if it can improve thinking and memory problems in adults with schizophrenia. You may join if your schizophrenia is stable and you take only one antipsychotic medication.
Little Rock, ArkansasAges 18–55 - NCT07208019Recruiting
Electroacupuncture for memory and thinking after stroke
This study tests whether electroacupuncture (using tiny electric pulses through thin needles) can help improve memory, focus, and thinking after a stroke. If you have mild to moderate thinking problems after a stroke, this treatment may help support your recovery.
Hangzhou, ZhejiangAges 35–80 - NCT06029114Enrolling by invitation
Brain scan study for memory problems
This study uses a special MRI to look at brain stiffness in people with normal memory, mild memory problems, or Alzheimer's disease. The goal is to see if this scan can help tell the difference between these groups.
Rochester, MinnesotaAges 18–100 - NCT07287410Recruiting
Assessing thinking and daily life in dementia and MCI
This study looks at how dementia or mild cognitive impairment affects thinking, daily living, and mood. The goal is to better understand these conditions by doing careful assessments.
Messina, MEAges 50–86 - NCT06043765Recruiting
Brain stimulation and memory training for glioma patients
This trial tests a combination of brain stimulation (rTMS) and cognitive strategy training to help improve memory and thinking in people with glioma. If you have a stable brain tumor and notice problems with focus or memory, you may be able to join.
AmsterdamAges 18–80 - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT06088212Recruiting
Heart failure treatment to help thinking and memory
This trial tests whether better managing heart failure after a hospital stay can protect against thinking and memory problems. It is for people who have heart failure and have had some cognitive difficulties.
Hobart, TasmaniaAges 18 years+ - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT06553235Recruiting
App-based sleep and memory help for breast cancer survivors
This study tests whether an app-based program can improve sleep and thinking problems (like concentration and memory) in people who finished breast cancer treatment 1-5 years ago. If you have trouble sleeping and/or notice changes in your memory or focus, this trial may be able to help.
Aarhus NAges 18 years+ - NCT07729969Recruiting
Digital brain training for cancer survivors
This study tests a digital program to help with memory and thinking problems that some people experience after cancer treatment. It is designed for survivors who finished chemotherapy recently and have access to a computer or tablet at home.
Bilbao, BizkaiaAges 18 years+ - NCT07711171RecruitingPhase 4
Canagliflozin for type 2 diabetes with mild memory problems
This trial tests whether the diabetes drug canagliflozin can help people with type 2 diabetes and mild cognitive impairment. It may slow down memory and thinking problems while also improving blood sugar control.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT07647380Recruiting
Brain Stimulation to Help Thinking in Schizophrenia
This trial tests a non-invasive brain stimulation technique called transcranial electrical stimulation (TIS) to improve thinking and memory problems in people with schizophrenia. Researchers want to see if this treatment, combined with antipsychotic medications, can help you think more clearly and function better in daily life.
Changsha, HunanAges 18–50 - NCT06286722Recruiting
Better rehab for seniors with hip fracture and memory issues
This trial tests a new rehab program for older adults who recently broke a hip and also have mild to moderate memory problems. The program aims to help them recover better after surgery.
FrederiksbergAges 65 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06969066Recruiting
Memory training for insomnia with memory problems
This trial tests memory training for people who have both insomnia and mild memory issues. It aims to see if this training can improve sleep and memory.
BeijingAges 8 years+ - NCT07652775Recruiting
Brain stimulation and exercise for memory and mood
This study tests whether combining rTMS (a non‑invasive brain stimulation) with aerobic exercise can improve memory, thinking, and mood in older adults who have mild memory problems and depression. It may offer a safe, drug‑free way to help both brain health and emotional well‑being.
Taipei, Taipei CityAges 65–90
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.