Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT04935619Recruiting
Testing cannabis abstinence effects in depression symptoms
This study looks at how stopping cannabis for a period of time may affect depression symptoms and thinking/memory. You might benefit by getting close monitoring of mood and cognition while researchers compare changes during cannabis abstinence.
Toronto, OntarioAges 18–55 - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT04949360Recruiting
Digital CBT-i program for insomnia using a tablet
This trial tests a phone or tablet app-based program based on CBT-i, a structured therapy that helps improve sleep habits and reduce insomnia symptoms. It may help if you have ongoing insomnia and prefer a digital approach.
São Caetano do Sul, São PauloAges 20–60 - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT05062369Recruiting
Brain stimulation plus training to support alcohol abstinence
This study tests whether a combination of brain stimulation (tDCS) and cognitive training can help people with alcohol use disorder stay abstinent. You may be included if you are currently not drinking and can commit to the program timeline.
Minneapolis, MinnesotaAges 18–65 - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT05106036Recruiting
Lowering BP targets to prevent memory and thinking decline
This study tests whether setting a lower blood pressure goal can help prevent future memory and thinking problems in older adults. It compares a more intensive blood pressure plan with usual care to see if it better protects the brain over time.
Dallas, TexasAges 70 years+ - NCT05117255Recruiting
Online therapy study for anxiety in residential alcohol treatment
This study tests an internet-based, interactive version of cognitive behavioral therapy (CBT) for anxiety symptoms. It’s designed for people getting mainly alcohol-focused treatment in a residential program, to see if the online approach works and is feasible for you.
Minneapolis, MinnesotaAges 18–65 - NCT05132517Recruiting
Magnesium to support thinking after stroke
This trial studies whether magnesium can help improve or protect thinking skills after a stroke. It may be offered to people who did not already have memory or thinking problems before their stroke.
Hessisch Oldendorf, Lower SaxonyAges 18 years+ - NCT05144516Recruiting
Video support program for cancer and mild memory problems
This study tests a video-based, “dyad” (patient plus family caregiver) coaching program for people with cancer and mild memory trouble (mild cognitive impairment). It may help by improving coping and communication during cancer care.
Durham, North CarolinaAges 18–100 - NCT05155137RecruitingPhase 3
Daily pill and home risk check to prevent stroke and memory loss
This Phase 3 trial tests whether a daily “polypill” plus a simple home risk-check plan can lower the chance of stroke and future thinking/memory problems. It is aimed at adults at moderate risk but who have not had stroke or heart disease before.
Porto Alegre, Rio Grande do SulAges 50–75 - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05215353RecruitingPhase 4
Music therapy or talk therapy for anxiety after cancer
This study compares music therapy and cognitive behavioral therapy (CBT) to see which better reduces anxiety in people who have had cancer. You may be randomly assigned to one of the two therapy programs and will join sessions by video call.
Miami, FloridaAges 18 years+ - NCT05250349Recruiting
Ultrasound brain blood flow and thinking in stable heart failure
This trial studies whether a noninvasive ultrasound test of blood flow in the brain, along with memory and thinking questionnaires, can help explain thinking changes in people with stable heart failure. It may help researchers better understand why some people develop cognitive (thinking) difficulties as heart failure progresses.
Krakow, MPAges 18 years+ - NCT05268861Recruiting
Understanding brain learning after stroke during arm training
This study looks at how thinking and brain processes affect learning to move your arm after a stroke. You may be asked to do arm tasks in a way that helps the researchers understand what helps or limits motor learning.
Laval, QuebecAges 40–75 - NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05304104Recruiting
Eating disorder care program for vets with binge problems
This trial looks at how to build a more fair and easy-to-access system of care for eating disorders within the VA and related groups. You may be able to take part if you are a VA user and have bulimia or binge eating, and can safely complete surveys and treatment planning.
West Haven, ConnecticutAges 18 years+ - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT05355389Recruiting
Home online rehab to improve thinking and movement in MS
This study tests whether doing cognitive-and-movement rehabilitation at home through telehealth helps people with multiple sclerosis (MS). It likely looks at changes in thinking performance and physical function while also checking safety with brain and electrical tests.
BrusselsAges 18–65 - NCT05375513Recruiting
Home exercise and brain-health support for mild memory trouble
This study tests a program you do at home (with online coaching) to help people with mild memory problems (“mild cognitive impairment”) improve thinking and brain health. It also focuses on lowering extra risk factors (like low activity, poor sleep, diet, or heart/metabolic risks).
Edmonton, AlbertaAges 60–85 - NCT05396248Recruiting
Memory training study for older adults with mild memory problems
This trial tests an approach to improve learning and memory in people age 60+ with amnestic mild cognitive impairment (a specific type of early memory problem). It may help by supporting memory and learning skills, but it also has medication and health-history requirements.
Ann Arbor, MichiganAges 60 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,028 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.