Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 893 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06579911Recruiting
Micro-ultrasound vs. MRI for prostate biopsy
This trial compares two advanced imaging techniques—high-frequency micro-ultrasound and multiparametric MRI—to guide biopsies for men who may have aggressive prostate cancer. The goal is to see which method better detects cancer while reducing unnecessary biopsies.
Salzburg, State of SalzburgAges 18–99 - NCT07620951RecruitingPhase 1
How Your Body Processes an Experimental Cancer Drug
This is an early-stage study testing how a new cancer medication (zorifertinib) moves through and leaves a healthy male body. Researchers use a special radioactive marker to track the drug so they can understand how it works and how safe it is.
Suzhou, JiangsuAges 18–45 - NCT06625034RecruitingPhase 3
Comparing two radiation planning methods for prostate cancer
This trial tests two ways to plan radiation treatment for prostate cancer: one using a computer program (RapidPlan) and the other using human experts. The goal is to see if the computer-assisted method works as well or better.
Scottsdale, ArizonaAges 18 years+ - NCT06641310Recruiting
Exercise therapy trial for people with familial adenomatous polyposis
This trial tests whether a home-based exercise program can help people with familial adenomatous polyposis (FAP) who have rectal polyps. You may qualify if you have FAP, have not had your rectum removed, have at least 5 rectal polyps larger than 2 mm, and are currently inactive.
Ann Arbor, MichiganAges 18 years+ - NCT06643793RecruitingPhase 2
Irinotecan liposome combo for advanced colorectal cancer
This trial tests a new form of the chemotherapy drug irinotecan (called irinotecan liposome) combined with two other chemo drugs and a targeted therapy (bevacizumab) for people with advanced colorectal cancer that has already been treated with oxaliplatin. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Nanjing, JiangsuAges 18–75 - NCT07685847Recruiting
Suppository for chronic prostatitis or pelvic pain relief
This trial tests a rectal suppository (Prospidol®) to see if it can relieve pain and other symptoms in men with long-term prostatitis or pelvic pain. It is for men who have not had treatment recently and have no signs of infection or other serious illnesses.
Avellino, AvellinoAges 18–60 - NCT06817668Recruiting
Testing a new radiation approach for prostate cancer
This study is testing a new way of giving radiation for prostate cancer, called ePUHRT, combined with a standard brachytherapy boost (a small radioactive implant placed inside the prostate). It aims to see if this approach is well-tolerated and safe for people with higher-risk prostate cancer.
Indianapolis, IndianaAges 18 years+ - NCT06841211Recruiting
Optimizing prostate biopsy for multiple MRI lesions
This study aims to find the best way to take tissue samples (biopsies) from the prostate when MRI shows more than one suspicious spot. It will help doctors know exactly where to biopsy to reduce false negatives and avoid missing cancer.
Beijing, Beijing MunicipalityAges 18–85 - NCT06923657Recruiting
PSMA PET/MRI for guiding biopsy after negative MRI
This study tests whether a special type of PET/MRI scan (PSMA PET/MRI) can help doctors find hidden prostate cancer in men who have a rising PSA but previous negative biopsies and a non-suspicious MRI. It aims to improve detection without skipping needed treatment.
Fuzhou, FujianAges 30–85 - NCT06930586Recruiting
Metabolic brain imaging for rectal cancer prognosis
This trial studies how brain metabolism changes in people with rectal cancer and whether those changes can help predict outcomes. It uses a special type of PET imaging to look at brain activity.
Henan, HenanAges 18 years+ - NCT06946771Recruiting
MRI and prostate lesions: understanding diagnosis and prognosis
This trial uses MRI scans to study prostate lesions and see how they relate to diagnosis, pathology, and long-term outcomes. It may help patients with concerns about prostate health get more detailed imaging.
Wuhan, HubeiAges 18 years+ - NCT06983639Recruiting
Fecal test vs. colonoscopy follow-up after polyp removal
This trial compares using a simple stool test (FIT) versus a repeat colonoscopy to check for new polyps in people who have already had an advanced adenoma removed. It aims to see if the stool test is a safe and effective alternative for routine follow-up.
Arendal, AgderAges 40–75 - NCT07172685Recruiting
Triple therapy plus HIFU for high-tumor-burden prostate cancer
This trial tests a combination of hormone therapy, chemotherapy (docetaxel), and a targeted drug (apalutamide) with a focused ultrasound procedure (HIFU) for men with prostate cancer that has spread to many bones or organs. It may help control the cancer more effectively.
Jinan, ShandongAges 18 years+ - NCT05080673Recruiting
Colonoscopy planning for small, noncancerous colon polyps
This trial tests whether people with 1–2 small, noncancerous colon polyps should get their next colonoscopy after 5 years or after 10 years. It may help reduce unnecessary procedures or find cancers earlier if the shorter interval is safer for you.
Fairbanks, AlaskaAges 45–70 - NCT07271017RecruitingPhase 1
Robot-assisted prostate biopsy using a new ultrasound probe
This trial tests a robot-assisted method for taking prostate biopsies using a new type of ultrasound probe. It may help men with certain high-risk features get a more precise diagnosis.
Baltimore, MarylandAges 40–75 - NCT07299071Recruiting
Can AI make screening colonoscopy better at finding precancerous polyps?
This study tests whether artificial intelligence (CAD) can help doctors find more polyps during screening colonoscopy, with the goal of lowering the risk of advanced adenomas (precancerous growths) over 3 years.
BayonneAges 18 years+ - NCT07319364RecruitingPhase 1
Fecal transplant study for cancer treatment side effects
This trial tests whether fecal transplants (putting healthy donor bacteria into your gut) can help with side effects like diarrhea, constipation, or nausea caused by cancer treatments. It is for people with advanced gastrointestinal cancer who are about to start their fourth round of chemo or targeted therapy.
Zhejiang, HangzhouAges 18 years+ - NCT01102556Recruiting
Pancreas disease registry for people at risk or with pancreatic cancer
This study collects health information and stored samples (biospecimens) to learn more about pancreatic diseases, including cancer and early warning changes. It may help researchers understand who is at higher risk and improve future testing and care.
New York, New YorkAges 18–85 - NCT02102477Recruiting
Surgery or radiation for prostate cancer in the pelvis
This trial compares surgery versus radiation for men with locally advanced prostate cancer that has not spread to distant sites. It aims to see which treatment works better and is easier to manage for people like you.
AalborgAges 18–75 - NCT02669992Recruiting
Compare closure methods for a loop ileostomy after rectal cancer
This trial studies which technique works best to close a loop ileostomy after rectal cancer surgery. It compares different closure methods to see which is safer and more effective for patients.
GothenburgAges Any age - NCT02871726Recruiting
Robot-assisted ultrasound biopsy of the prostate
This trial tests a robot-assisted method to take prostate tissue samples using an ultrasound probe placed through the rectum. It may help patients and doctors get clearer biopsy results when there are early warning signs of prostate problems, before a cancer diagnosis is confirmed.
Baltimore, MarylandAges 45–75 - NCT00102544Enrolling by invitation
Tracking Devices to Find Abnormalities During Medical Procedures
This study tests technology that uses imaging scans to help doctors locate and reach abnormalities during surgical or interventional procedures. The goal is to make these image-guided procedures more accurate and safer for patients.
Bethesda, MarylandAges 18–120 - NCT07428356Recruiting
Sound waves for liver tumors
This study tests a new, noninvasive treatment called histotripsy that uses sound waves to destroy small liver tumors. It is for people whose liver cancer hasn't spread much and who haven't had success with or can't have surgery or other standard treatments.
SingaporeAges 21–99 - NCT07456852RecruitingPhase 1/Phase 2
Can vasodilators help with chemo side effects in GI cancer?
This trial tests two drugs (isosorbide mononitrate and diltiazem) to see if they can prevent blood vessel damage caused by chemotherapy drugs like 5-FU or capecitabine in people with gastrointestinal cancers.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 893 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.