Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 893 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07650344Recruiting
AI Tool to Detect Flat Colon Polyps During Screening
This study tests whether artificial intelligence can help doctors spot certain flat polyps (called sessile serrated lesions) during routine colonoscopy screening. Finding these polyps early may help prevent colorectal cancer.
SingaporeAges 40–80 - NCT07052214RecruitingPhase 3
PSMA PET plus MRI to find prostate cancer
This trial tests if combining a PSMA PET scan with an MRI can better detect clinically significant prostate cancer than MRI alone. It may help men who have not had a prostate biopsy before and have certain risk factors.
Los Angeles, CaliforniaAges 18 years+ - NCT06131840RecruitingPhase 1
Study of SGN-CEACAM5C for advanced solid tumors
This trial tests a new drug called SGN-CEACAM5C in people with advanced solid tumors that have not responded to other treatments. The drug targets a protein on cancer cells to try to stop them from growing.
Phoenix, ArizonaAges 18 years+ - NCT03587480Recruiting
Surgery methods after chemo-radiation for stage 3 rectal cancer
This trial compares two different surgery approaches after chemo-radiation for stage 3 rectal cancer. It aims to see which operation helps control the cancer more effectively while keeping surgery as safe as possible.
Guangzhou, GuangdongAges 18–75 - NCT04949646Recruiting
Nerve monitoring during rectal cancer surgery
This trial studies whether checking pelvic nerve signals during rectal cancer surgery (total mesorectal excision) is helpful. It may help surgeons avoid nerve injury while removing the cancer.
LarissaAges 18–90 - NCT05076500Recruiting
How radiotherapy changes a tumor’s immune response
This study looks at how a tumor’s immune system responds when you receive radiotherapy. It involves taking a planned pre-treatment biopsy so researchers can study immune and tumor changes and see if radiotherapy affects them.
ManchesterAges 18 years+ - NCT05346796Recruiting
Online care plan program for colon or rectal cancer survivors
This trial tests whether a survivorship (after-treatment) health plan delivered through an online health record helps people after colon or rectal cancer treatment. It may help you organize follow-up care and stay on track with recommendations.
Indianapolis, IndianaAges 18–99 - NCT05629494RecruitingPhase 4
Ibuprofen vs PSA blood test for prostate evaluation
This trial studies whether an anti-inflammatory medicine (ibuprofen) changes prostate-specific antigen (PSA) blood test results to help decide on next diagnostic steps like MRI or biopsy. It may help people with an elevated PSA understand whether follow-up testing is more or less likely to be needed.
Chicago, IllinoisAges 18–80 - NCT05689775Recruiting
Robot-assisted reconstruction using tummy muscle flap after surgery
This trial studies a specific way to rebuild the pelvic floor (and sometimes the vagina) after major rectal or anal cancer surgery. It uses robotic surgery and a flap taken from your tummy muscle to help close and reconstruct the area.
OsloAges 18 years+ - NCT05710861Recruiting
Focal HIFU versus prostate surgery: cost and quality of life
This trial compares focal HIFU (a targeted heating treatment inside the prostate) with prostate surgery, looking at overall cost and quality of life. It may help people with certain early, limited prostate cancers understand which option fits best for them.
BesançonAges 50–75 - NCT05782010Recruiting
Testing a hemorrhoid device for grade II or III hemorrhoids
This study tests how safe and well a hemorrhoid treatment device (PexyEazy®) works for adults with moderate-to-severe hemorrhoids (grade II–III). You may be a candidate if you fit the hemorrhoid grade and medical safety requirements and can follow the study plan.
FrölundaAges 18–84 - NCT05791396RecruitingPhase 1/Phase 2
Fecal microbiome therapy to clear hard-to-treat gut germs
This trial looks at a treatment made from stool donors (called fecal microbiome therapy) to help remove carbapenem-resistant gut bacteria in the body. It’s mainly for adults who recently tested positive for these bacteria on a rectal swab, and it checks whether the therapy can help eradicate the germs.
RomaAges 18–85 - NCT05792722Recruiting
Testing a prostate-sparing bladder surgery for bladder cancer
This trial studies whether a “prostate-sparing” radical cystectomy is safe and effective for bladder cancer patients who are having surgery. It aims to see if this approach can treat bladder cancer while reducing prostate-related side effects.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05864196RecruitingPhase 1
Testing two-shot prostate radiation with MRI-guided planning
This early-phase study tests a prostate radiation approach given in two treatments, planned using MRI. It’s designed for men with lower-to-intermediate risk prostate cancer and aims to see if this method is safe and works well.
Mineola, New YorkAges 18 years+ - NCT06018961Recruiting
Study of bowel slowdown after digestive surgery
This study is looking at how common and severe a condition called 'postoperative ileus' (temporary slowdown of the bowel) is after planned digestive tract surgeries. It will help doctors better understand and manage this complication.
ToulouseAges 18 years+ - NCT06111313RecruitingPhase 2
Prostate cancer trial testing targeted radiation with hormone therapy
This trial tests a new radiation approach for prostate cancer that has not spread. It combines different types of radiation with or without hormone therapy to see if this approach works better with fewer side effects.
Miami, FloridaAges 35–85 - NCT06175325Recruiting
Embolization for hemorrhoids: a procedure without surgery
This trial tests a minimally invasive procedure called embolization (blocking the blood supply) to treat hemorrhoids that bleed or come back. It may be a good option if you want to avoid surgery.
Stoke-on-TrentAges 18 years+ - NCT06302595Recruiting
MRI-guided prostate biopsy for cancer diagnosis
This trial uses MRI to guide a biopsy of the prostate, aiming to better detect cancer in men with abnormal PSA levels, a lump, or a suspicious MRI finding.
Boston, MassachusettsAges 30 years+ - NCT06303622Recruiting
Comparing two MRI-guided biopsy methods for prostate cancer
This trial compares two ways to guide a prostate biopsy using MRI images, to see which better detects clinically significant prostate cancer in men with suspicious MRI findings.
Hong KongAges 18 years+ - NCT07692152RecruitingPhase 3
Immunotherapy vs. chemo for MS anal cancer trial
This trial tests sintilimab (a type of immunotherapy) against mitomycin plus chemotherapy with radiation for anal cancer that hasn't spread. It aims to find a better treatment with fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT06523634Recruiting
SBRT for rising PSA after prostate removal
This trial tests a precise type of radiation (called SBRT) to the prostate bed for men whose PSA starts rising after prostate removal surgery. It aims to see if this targeted approach can effectively treat the recurrence without needing long-term hormone therapy.
AalstAges 18 years+ - NCT06532877Recruiting
Telephone support for advanced GI cancer and caregivers
This study offers telephone-based support for people with advanced gastrointestinal cancer who are experiencing fatigue, and for their family caregivers. It aims to help both you and your caregiver manage the challenges of cancer care together.
Chicago, IllinoisAges 18 years+ - NCT06535802Recruiting
Prostate cancer support for Black men in Florida
This study tests a new program to help Black men recently diagnosed with prostate cancer. It aims to provide support right after diagnosis to improve care and well-being.
Jacksonville, FloridaAges Up to 80 years - NCT06578637Recruiting
BHB supplement study for familial adenomatous polyposis
This trial tests whether taking a supplement called beta-hydroxybutyrate (BHB) can help prevent polyps in people with familial adenomatous polyposis (FAP), a condition that causes many polyps in the colon. The study has two parts: one for people who have already had colon surgery, and another for those who still have their colon.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 893 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.