Clinical trials
Colorectal clinical trials
Below are recruiting colorectal clinical trials, each written for real people, not researchers. We’re tracking 1,202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07830576Recruiting
Predicting survival after liver surgery for colorectal cancer
This study uses your liver MRI scans and medical information to build a tool that predicts survival after surgery for colorectal cancer that has spread to the liver. It may help doctors better understand your outlook and plan care.
Hefei, AnhuiAges 18–80 - NCT07776353Recruiting
Understanding weight loss in advanced cancer
This study looks at how weight loss and muscle loss affect people with advanced cancer. It aims to find different types of weight loss to better guide treatment and care.
Pleasanton, CaliforniaAges 18 years+ - NCT07759921Recruiting
Mindfulness program for couples facing metastatic colorectal cancer
This study tests a mindfulness-based program for couples facing metastatic colorectal cancer. It aims to help reduce distress and improve coping for both patients and their partners.
Aurora, ColoradoAges 18–85 - NCT06629051Recruiting
Long-term follow-up after berberine treatment trial
This study checks on people who took berberine in an earlier trial to see how they are doing 6 years later. It helps researchers understand the long-term effects of the treatment.
ShanghaiAges Any age - NCT07559825Recruiting
Understanding Early-Onset Colorectal Cancer in Younger Patients
This study looks at colorectal cancer in younger patients who wouldn't normally be screened. Researchers want to understand how this cancer develops in people under the typical screening age.
Dallas, TexasAges 35 years+ - NCT06287671Recruiting
Colorectal Surgery Tissue Study for Better Understanding of Disease
This study is collecting tissue samples from people having surgery on their colon or rectum to better understand colorectal diseases. It may help researchers learn more about conditions like cancer, polyps, or inflammatory bowel disease.
HillerødAges 18 years+ - NCT07463599RecruitingPhase 1/Phase 2
Tegavivint for advanced colorectal cancer after other treatments
This early-phase trial tests an experimental drug called tegavivint for people with advanced colorectal cancer who have already tried several standard treatments. It aims to see if the drug can shrink or slow the growth of tumors.
Scottsdale, ArizonaAges 18 years+ - NCT07446322RecruitingPhase 2
Study of a new drug plus standard chemo for advanced colorectal cancer
This trial tests if adding the experimental drug pelareorep to standard chemotherapy (FOLFIRI) and bevacizumab can help people with a specific type of advanced colorectal cancer that has a RAS mutation and is not caused by high microsatellite instability. You may be able to join if you've already tried one type of chemotherapy and it stopped working or you couldn't tolerate it.
Homewood, AlabamaAges 18 years+ - NCT07407465RecruitingPhase 2
Study of a new drug combo for advanced HER2-positive colorectal cancer
This trial tests a combination of three drugs (trastuzumab deruxtecan, capecitabine, and bevacizumab) as the first treatment for people with HER2-positive colorectal cancer that has spread or cannot be removed by surgery. The goal is to see if this combination can shrink tumors and help patients live longer.
LyonAges 18 years+ - NCT06715384Recruiting
Testing a new camera tool to measure colon polyps
This trial tests a computer-assisted measurement system during a colonoscopy to see if it can more accurately measure polyps. You might consider this if you are scheduled for a routine colonoscopy for screening or monitoring.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07327489Recruiting
Live tumor biopsy study to predict immunotherapy response
This trial studies how well immunotherapy might work by analyzing fresh tumor biopsies. It may help predict which treatments are best for your cancer.
Fort Smith, ArkansasAges 18 years+ - NCT07294690Recruiting
Virtual reality training before colorectal cancer surgery
This study uses virtual reality training before colorectal cancer surgery to see if it helps reduce anxiety and prepare you better for the procedure, leading to a smoother recovery.
IstanbulAges 18–70 - NCT07244705RecruitingPhase 1/Phase 2
Study of ABT-301 plus tislelizumab and bevacizumab for advanced colorectal cancer
This trial tests a new drug combination (ABT-301, tislelizumab, and bevacizumab) for people with a specific type of advanced colorectal cancer that has not responded to at least two prior treatments. It aims to see if this combination can help shrink tumors or slow the disease.
Liverpool, New South WalesAges 18 years+ - NCT07237984Recruiting
COCO study for colorectal cancer screening
This trial looks at substances in your body to help find colorectal cancer earlier. It is for people who are already scheduled for a colonoscopy, either because of a positive stool test or cancer symptoms.
HillerødAges 18 years+ - NCT07230262Recruiting
Robotic vs. laparoscopic surgery for IBD patients
This study compares two types of minimally invasive surgery—robotic and laparoscopic—for people with inflammatory bowel disease (Crohn's or ulcerative colitis) who need elective colon or rectal surgery. It aims to find out which approach might be better for recovery and outcomes.
Leuven, Vlaams BrabantAges 18 years+ - NCT07225309Recruiting
Meaning-Centered Therapy for Mexican Adults with Advanced Cancer
This study tests a therapy program called Meaning-Centered Therapy designed to help adults in Mexico with advanced cancer find meaning and improve their well-being. It involves sessions delivered by trained providers at the National Cancer Institute in Mexico (INCan).
New York, New YorkAges 18 years+ - NCT07224724Recruiting
Exosome liquid biopsy for colorectal cancer spread
This study uses a blood test to detect if colorectal cancer that has spread to the liver has also spread to other parts of the body. It may help doctors better understand how the cancer is moving and guide treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT07208786Recruiting
Vacuum therapy to prevent leaks after colorectal cancer surgery
This trial tests whether using a special vacuum device inside the surgical connection (anastomosis) right after surgery can help prevent leaks. If you are having surgery for colorectal cancer, this treatment might reduce your risk of a serious complication.
Nanchong, SichuanAges 18–85 - NCT06930118RecruitingPhase 2
Study of 4 drugs for advanced colorectal cancer
This trial tests a combination of four drugs for people with advanced colorectal cancer who have already tried at least two other treatments. The goal is to see if this new mix can help shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT06307938Recruiting
Liquid biopsy test for colorectal cancer before colonoscopy
This trial tests a simple blood test (liquid biopsy) to find cancer signals in the DNA of people being called for a colonoscopy. If you are scheduled for a colonoscopy, your blood sample could help doctors detect colorectal cancer earlier and plan better treatment.
LevangerAges 18 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT06949982RecruitingPhase 2
Comparing two treatments for advanced colorectal cancer with RAS mutations
This trial tests if a combination of hydroxychloroquine, methotrexate, capecitabine, and bevacizumab works better than regorafenib for people with metastatic colorectal cancer that has a RAS gene mutation and has stopped responding to at least two prior treatments.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT07144683Recruiting
Colorectal surgery leak study
This trial is studying how often leaks happen after colorectal surgery that connects two parts of the intestine. It may help doctors better understand and prevent this complication.
Minya, Minya GovernorateAges 18–80 - NCT07095517RecruitingPhase 1
Preventing early-onset colorectal tumors with tirzepatide
This study tests if tirzepatide can help prevent early-onset colorectal tumors in people aged 18-50 who have had certain types of polyps removed. It aims to find risk factors and ways to stop colorectal cancer before it starts.
Boston, MassachusettsAges 18–50
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Common questions
- Are there clinical trials for colorectal?
- Yes. Clin2 currently lists 1,202 recruiting colorectal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.