Clinical trials
Comorbidity clinical trials
Below are recruiting comorbidity clinical trials, each written for real people, not researchers. We’re tracking 121 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06062953RecruitingPhase 2/Phase 3
Melatonin or low-dose quetiapine for insomnia in psychiatric disorders
This study tests if melatonin, a low dose of quetiapine, or a placebo can help people with a psychiatric condition who also have trouble sleeping. You may qualify if you have insomnia at least 3 times a week and your sleep problem has lasted 3 months or longer.
Copenhagen NVAges 16–64 - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65 - NCT07165236Recruiting
Bladder tumor surgery and memory changes study
This study looks at how bladder tumor surgery might affect thinking and memory. It checks blood markers to see if they are linked to any mental changes after the operation.
Osijek, CroatiaAges 18–80 - NCT07146503Recruiting
Esketamine Nasal Spray for Treatment-Resistant Depression in Real Life
This study tests esketamine nasal spray (a fast-acting antidepressant) for people with treatment-resistant depression who haven't gotten better after trying at least two other antidepressants. It looks at how well the spray works in everyday doctor's offices, not just in research clinics.
Genova, GeAges 18–74 - NCT07118683Recruiting
Brazilian health study for people with HIV or AIDS
This study is creating a record of chronic health conditions (like heart disease, diabetes, or high blood pressure) in people living with HIV or AIDS in Brazil. Joining helps researchers better understand and care for the health needs of people like you.
Goiânia, GoiásAges 18 years+ - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07113665RecruitingPhase 1
Focused ultrasound brain treatment for severe anorexia
This trial tests if focused ultrasound can help people with severe anorexia nervosa who also have obsessive-compulsive disorder or major depression. It is for those who have not gotten better with other treatments.
Toronto, OntarioAges 18–65 - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07067619Recruiting
Pain acceptance training for emotional and physical distress
This trial tests a training program to help people accept chronic pain and emotional distress. It looks at how thinking patterns might help or hinder progress.
HaifaAges 18–70 - NCT07041073Recruiting
Brain training for emotion control in depression
This trial tests if a non-invasive brain training technique called neurofeedback can help people with major depression improve how they manage emotions. You participate by doing computer tasks while your brain activity is measured and shown back to you, teaching you to regulate your emotions better.
Sabadell, Barcelona, CataluñaAges 18–65 - NCT07009158RecruitingPhase 1/Phase 2
Ketamine plus therapy for pain and PTSD
This trial tests if ketamine combined with talk therapy helps people with both chronic pain and PTSD. Participants receive ketamine through an IV in group therapy sessions over several weeks, with the goal of reducing pain and PTSD symptoms.
Kingston, OntarioAges 18–64 - NCT06968832Recruiting
Prolonged therapy for PTSD and substance use
This trial tests a therapy that helps people with both post-traumatic stress disorder (PTSD) and a substance use disorder (SUD). You'll receive extended therapy sessions to reduce PTSD symptoms and support your recovery from substance use, while continuing your current substance use treatment.
Jacksonville, FloridaAges 18 years+ - NCT06958640Enrolling by invitation
Da Qing offspring health study
This study looks at the health of children, grandchildren, and great-grandchildren of people who took part in a diabetes prevention study in Daqing, China. It aims to understand how their family history affects their health over time.
Beijing, Beijing MunicipalityAges Any age - NCT06929598Recruiting
Shiatsu for chronic pain in children and teens
This study tests whether Shiatsu—a gentle, hands-on therapy—can help reduce chronic, non-inflammatory pain in children and adolescents. If you or your child have had long-term pain without inflammation and are already being seen at a specific pain clinic in Tel Aviv, this trial might be a good fit.
Tel Aviv, Tel AvivAges 10–18 - NCT06923683Enrolling by invitation
Social skills treatment for brain injury
This trial tests a treatment called T-ScEmo for people with brain injury who have trouble with social skills and emotions. The treatment involves you and a support person (like a partner or close friend) working together to improve social understanding and behavior.
Boekel, North BrabantAges 18–70 - NCT06906328Recruiting
ADHD and addiction: can cognitive training help?
This study tests whether adding a cognitive remediation program to methylphenidate (a medication for ADHD) improves treatment response in adults who have both ADHD and a substance use or behavioral addiction. It aims to help patients manage symptoms better over the short and medium term.
Brest, Brittany RegionAges 18–99 - NCT06797726Recruiting
CBT for adults with ADHD and behavioral addiction
This trial tests if cognitive-behavioral therapy (CBT) can help people who have both ADHD and a behavioral addiction (like gambling or gaming). If you qualify, you would attend therapy sessions to see if it improves your symptoms.
BrestAges 18 years+ - NCT06858527Recruiting
Combined ADHD and substance use treatment study
This study tests a combined treatment for adults who have both ADHD and a substance use disorder. It looks at whether an integrated approach helps people better manage both conditions together.
ParisAges 18 years+ - NCT06872398Recruiting
Medical conditions in bipolar disorder
This study looks at medical health issues in people with bipolar disorder. It aims to understand how physical health conditions affect the illness, which could lead to better care.
CréteilAges 18–65 - NCT06736444Recruiting
Sleep and Substance Use Help for Young Adults
This study tests a brief program to help young adults who struggle with sleep and also use alcohol or cannabis. The program teaches skills to improve sleep quality and reduce risky substance use.
Seattle, WashingtonAges 18–29 - NCT05293366Recruiting
Long COVID study testing supportive care for multiple body systems
This study looks at people who have recovered from COVID-19 but still deal with long-term problems. It aims to better understand (and potentially help with) ongoing issues that can affect hormones, metabolism, mood, muscles, the heart, lungs, and skin.
NaplesAges 18 years+ - NCT05379556Recruiting
Study for long COVID sexual and reproductive symptoms
This study is looking at people who have recovered from COVID-19 but still have ongoing (long COVID) sexual, reproductive, or related symptoms. Researchers want to learn about these lingering problems and what may help, based on your answers and study procedures.
Naples, ItalyAges 18 years+ - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06652776Enrolling by invitation
Italian COPD patient registry study
This study is creating a registry to better understand Chronic Obstructive Pulmonary Disease (COPD) in Italian patients. It will collect information from people with COPD to improve care and research.
Milan, MilanAges 40 years+
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Common questions
- Are there clinical trials for comorbidity?
- Yes. Clin2 currently lists 121 recruiting comorbidity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a comorbidity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a comorbidity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.