Clinical trials
Comorbidity clinical trials
Below are recruiting comorbidity clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT05204186Recruiting
AI Tool to Predict Health Outcomes After Bladder Removal Surgery
This study tests an artificial intelligence tool designed to predict how patients will recover after bladder cancer surgery. The AI analyzes existing medical information to help doctors better understand which patients might face complications based on their other health conditions.
Amiens, PicardieAges 18 years+ - NCT05578495Recruiting
Track daily movement to predict future health problems
This study looks at how active versus sedentary you are (often using a digital signature from your daily routine) to see how it relates to developing multiple health conditions over time. It may help researchers understand which activity patterns are linked with higher risk, especially in certain long-term illnesses.
Clermont-FerrandAges 18–90 - NCT05954741Recruiting
Rehab program to improve thinking in recent vascular memory problems
This trial tests a structured, multi-part rehabilitation program to help people with early dementia symptoms from vascular or mixed causes. If you qualify, you may be offered the rehab program and compared with another approach to see if thinking and daily function improve.
Montescano, PaviaAges 65–80 - NCT06579222Recruiting
Managing other health conditions in rheumatoid arthritis
This study looks at how to better manage health conditions like heart disease or diabetes in people with rheumatoid arthritis. Participants will work with their rheumatology clinic to improve overall health.
Waterloo, OntarioAges 18–80 - NCT07008456RecruitingPhase 2
Testing a new sugar-bead treatment for weight loss in obesity
This study tests a new treatment—small beads of sugar that release in the lower intestine—to help people with obesity and related health conditions lose weight. It compares two different doses of the beads plus a gel to a placebo (inactive treatment).
Tbilisi, K'alak'i T'bilisiAges 18–75 - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Dothan, AlabamaAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT07780188Recruiting
Lean beef in a healthy meal plan for teens with PCOS
This study tests whether adding lean beef to a healthy meal plan can help teens with PCOS improve their health. You'll follow a special diet and wear a small monitor to track your blood sugar, and the study may help you feel better and manage your condition.
College Station, TexasAges 11–17 - NCT07693608Enrolling by invitationPhase 2
Tirzepatide for weight loss in stimulant use disorder
This trial tests whether a weekly injection called tirzepatide (a diabetes and weight-loss medication) can help people with obesity and stimulant use disorder reduce stimulant use and lose weight. It aims to see if treating both conditions together improves outcomes.
Dallas, TexasAges 18–65 - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Birmingham, AlabamaAges 18 years+ - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT06305091Recruiting
DNA Changes in Veterans Exposed to Burn Pits
This study looks for DNA changes in veterans who were exposed to open burn pits during deployment. It aims to understand health risks from these exposures.
North Little Rock, ArkansasAges 25–70 - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Los Angeles, CaliforniaAges 12–17 - NCT07753421Enrolling by invitation
Health and function in older adults
This study looks at how memory, walking speed, and breathing muscle strength are related in older adults. It aims to understand these factors better to help maintain independence and quality of life.
IstanbulAges 60 years+ - NCT04748770Recruiting
Kidney Transplant Access for Obese Dialysis Patients
This study looks at whether obese patients who are starting dialysis can safely receive kidney transplants. Researchers want to understand how weight affects transplant success and access to this life-changing treatment.
AmiensAges 18 years+ - NCT05608772Recruiting
Revision weight-loss surgery after failed sleeve
This study looks at which revision surgery works best after a prior sleeve stomach operation that didn’t last. It tests switching to one of three procedures to help with weight regain, and it excludes more severe acid reflux cases.
Alexandria, Alexandria GovernorateAges 18–60 - NCT05352061Enrolling by invitation
HIV support program for people with mental health and life challenges
This study looks at how an HIV treatment and prevention program can be improved for people who have HIV plus psychosocial challenges, especially when HIV is not well controlled. You may be able to join if your HIV is recent and higher than target, and you fit one of the specific participant groups.
Miami, FloridaAges 18 years+
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Common questions
- Are there clinical trials for comorbidity?
- Yes. Clin2 currently lists 118 recruiting comorbidity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a comorbidity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a comorbidity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.