Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05822141Recruiting
Omega-3 effects on body fat in cold exposure
This study tests whether omega-3 (fish oil–type) changes how your body fat responds when you are exposed to cold. It may help researchers understand how to regulate “brown fat,” which can be involved in how your body uses energy during cold.
Bloomington, IndianaAges 18–40 - NCT05830591Recruiting
Gut microbiome study in autism in children
This trial studies differences in the gut bacteria (microbiome) between children with autism and healthy children. It may help researchers understand what roles the gut may play in autism and guide future treatments.
TriesteAges 1–17 - NCT05889624Recruiting
Study of treatments for childhood migraine headaches
This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.
Birmingham, AlabamaAges 10–17 - NCT05924295Recruiting
Study how ketone changes in the body with diet and fasting
This study looks at how your body processes “ketones,” which are energy molecules that rise with fasting or low carbohydrate intake. You may be asked to follow strict diet and activity rules before test days so researchers can see what affects ketone metabolism.
Novato, CaliforniaAges 20–70 - NCT05961059RecruitingPhase 1
Shigella vaccine safety study for healthy adults
This Phase 1 study tests a Shigella (gut infection) vaccine and additives to see how safe they are in healthy adults. If you qualify, you may help researchers understand whether the vaccine triggers any unwanted immune or stomach side effects.
LeidenAges 18–50 - NCT05966727Recruiting
Cholestyramine to lower stored pollutants in obese women
This study tests whether cholestyramine can lower blood levels of certain stored environmental pollutants (“POPs”) in women preparing for weight-loss surgery. If it works, it may help reduce pollutant levels that can build up in the body over time.
Nice, Alpes-MritimesAges 18–45 - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT05998187RecruitingPhase 3
Botox injections for fecal incontinence
This trial tests whether botulinum toxin (Botox) injections into the rectum can improve bowel control in people with active fecal incontinence. It aims to help those who haven't gotten better with standard treatments like diet changes or pelvic floor therapy.
Rouen, FranceAges 18 years+ - NCT06098742Recruiting
Comparing a new liquid antacid to chewable Riopan in healthy adults
This trial tests whether a new liquid antacid (Antareit) works as well as the chewable Riopan tablets in healthy people. It involves a small tube placed through your nose to measure stomach acid before and after taking the medication.
MoscowAges 18–45 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT06144021Recruiting
Kefir whey drink for muscle health in adults over 40
This study tests whether a fermented milk drink (kefir whey postbiotics) can help improve muscle mass in people over 40 who have low muscle. It is for generally healthy adults who are not taking certain medications or following special diets.
SeoulAges 40 years+ - NCT06183697Recruiting
Healthy Korean volunteers multi-omics database study
This study is building a database of genetic and other health information from healthy Korean volunteers. It involves providing samples and answering health questions to help future research.
SeoulAges 13–85 - NCT06220617Recruiting
Early detection of colorectal cancer using blood tests
This study is looking for people newly diagnosed with colorectal cancer or advanced adenoma to help find better ways to detect the disease early using advanced lab tests on blood samples.
Hangzhou, ZhejiangAges 18 years+ - NCT06222255Recruiting
Transanal irrigation for sleep issues after rectal cancer surgery
This trial tests if a special irrigation technique can improve sleep problems caused by low anterior resection syndrome (LARS) after rectal cancer surgery. It may help people who have ongoing bowel symptoms that disrupt sleep.
Seoul, Jongro-guAges 19–80 - NCT04976153RecruitingPhase 3
Stem cell implant to treat fecal urge incontinence
This Phase 3 study tests an implant made from a person’s own muscle-related cells to improve fecal “urge” leakage. It’s for adults whose symptoms haven’t improved enough with usual conservative treatments.
GrazAges 18 years+ - NCT06388863Recruiting
Fecal transplant for constipation in Parkinson's disease
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help relieve constipation in people with Parkinson's disease. FMT uses healthy donor stool to improve gut bacteria, which may ease constipation and possibly improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT06413368RecruitingPhase 2/Phase 3
Maralixibat for cystic fibrosis constipation
This trial tests a medicine called maralixibat to see if it helps children with cystic fibrosis who have chronic constipation that doesn't improve with standard treatments. The goal is to improve bowel movements and quality of life.
Los Angeles, CaliforniaAges 1–18 - NCT06442566RecruitingPhase 1/Phase 2
Enhancing opioid therapy for chronic pain with buprenorphine, counseling, and brain stimulation
This study is testing whether adding a medication (buprenorphine), counseling, and a type of brain stimulation (TMS) can improve long-term opioid therapy for chronic pain. If you have been taking prescription opioids daily for at least 3 months and have extra risk factors for opioid-related problems, this trial may offer you new ways to manage pain and reduce risks.
Charleston, South CarolinaAges 18 years+ - NCT06455813RecruitingPhase 4
Best laxative after hip fracture surgery
This trial is comparing different laxatives to help prevent constipation after hip fracture surgery. It is for older adults (65+) who recently had hip surgery and are not already using laxatives.
KoldingAges 65–110 - NCT06474507Recruiting
Calculus Bovis Sativus for Stroke Recovery
This study tests an investigational traditional Chinese medicine called Calculus Bovis Sativus (CBS) for people who have had an ischemic stroke or have small vessel disease in the brain. It aims to see if CBS can help recovery and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+ - NCT06475560Recruiting
Camera capsule endoscopy for colorectal disease diagnosis
This trial tests a camera pill (capsule endoscopy) as an alternative to a regular colonoscopy for people with colon or rectum symptoms. It's a simpler way to look inside your large intestine without a tube.
Odense CAges 18 years+ - NCT06488365Recruiting
Melanoma blood test using a new device (Cytophone)
This trial tests a new, non-invasive device called a liquid biopsy that looks for melanoma cells in your blood. It may help find cancer earlier without needing a needle biopsy.
Madison, WisconsinAges 18–80 - NCT06515821Recruiting
Improving colorectal cancer screening and diagnosis
This study collects data to improve how colorectal cancer is found and diagnosed. It compares new testing methods (like breath and stool tests) with standard colonoscopy in people with and without cancer or risk factors.
SofiaAges 18 years+
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 154 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.