Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06937814Recruiting
Effect of Humiome Post LB on Gut Comfort in Healthy Adults
This study tests a supplement called Humiome Post LB to see if it helps with mild digestive discomfort like bloating, irregular stools, and urgency. If you have frequent but not severe bowel issues (10-20 movements per week with loose stools) and are generally healthy, this may be for you.
London, OntarioAges 18–75 - NCT06929273RecruitingPhase 3
Long-term safety study of KarXT for bipolar I mania
This study tests the long-term safety of KarXT for people with bipolar I disorder who are having a manic or mixed episode. It is for people who either completed a previous KarXT study or are new to the study and have moderate to severe mania symptoms.
Glendale, ArizonaAges 18–65 - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT06888154Recruiting
Hot compress use after open abdominal surgery
This trial tests if applying a warm compress to the abdomen after open belly surgery can help recovery. It aims to see if this simple, drug-free method reduces pain or improves bowel function.
Merkez, KırşehirAges 18–65 - NCT06869941Recruiting
How gut health and fat tissue are linked in the brain
This study looks at how the bacteria in your gut might affect your fat tissue and brain. You may be able to join if you are scheduled to have surgery to remove fat tissue and are willing to sign a consent form.
Girona, GironaAges 20 years+ - NCT06837064Enrolling by invitation
Can a chatbot help manage Irritable Bowel Syndrome?
This study tests whether a chatbot can help adults with Irritable Bowel Syndrome (IBS) manage their symptoms. If you have been diagnosed with IBS, you may be able to join and use the chatbot as part of your care.
MoscowAges 18 years+ - NCT05427058Recruiting
Nerve blocks to treat hard-to-control cancer pelvic pain
This trial tests two types of pain-relieving nerve blocks for people with severe cancer pain in the pelvis or perineum that has not improved enough with standard stepwise pain medicines. It may help reduce pain and lessen bothersome side effects from pain pills.
Malang, East JavaAges 18 years+ - NCT06833684Recruiting
Comparing MOWOOT and trans-anal irrigation for constipation
This study tests two treatments for chronic constipation: a device called MOWOOT (which uses gentle abdominal massage) and trans-anal irrigation (a way to wash out the rectum). It is for people who have tried biofeedback therapy and still need help managing their constipation.
London, LondonAges 18 years+ - NCT06833866RecruitingPhase 1
Testing a natural compound with chemo for advanced colorectal cancer
This trial combines a natural substance called hydroxytyrosol (HT) with standard chemotherapy (5-FU and possibly other drugs) for people with advanced or metastatic colorectal cancer that hasn't been treated yet. The goal is to see if adding HT makes the treatment work better.
Houston, TexasAges 18 years+ - NCT06827977RecruitingPhase 2
Microbiome transplant for constipation and bloating in scleroderma
This study tests a microbiome transplant (friendly bacteria given as an enema or in capsules) to see if it helps with constipation and bloating in people with scleroderma. The goal is to improve digestive symptoms related to your condition.
Houston, TexasAges 18 years+ - NCT06805903Recruiting
Validating a survey on transanal irrigation adherence
This study tests a new survey to better understand how well people are following their transanal irrigation treatment. If you use this treatment for bowel issues, the researchers want to see if the survey accurately measures your routine.
ParisAges 18 years+ - NCT04788914Recruiting
Test saliva or blood markers to track kidney and leg disease treatment
This study looks at a gene marker (“lncRNA,” a natural molecule in the body) to see how well an oral absorbent, with or without probiotics, is helping people with chronic kidney disease (CKD) who also have blocked leg arteries. It may help doctors better measure treatment impact and tailor care.
Taipei, TaiwanAges 20 years+ - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT06738550Enrolling by invitation
Agave inulin for constipation in new dialysis patients
This study tests whether a natural fiber supplement called agave inulin can help with constipation and improve quality of life for people who have just started peritoneal dialysis for kidney failure.
Metepec, State of MexicoAges 18 years+ - NCT06455813RecruitingPhase 4
Best laxative after hip fracture surgery
This trial is comparing different laxatives to help prevent constipation after hip fracture surgery. It is for older adults (65+) who recently had hip surgery and are not already using laxatives.
KoldingAges 65–110 - NCT06727422RecruitingPhase 2
Rifaximin plus NAC for IBS with diarrhea
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06683521Recruiting
Understanding the immune system in FPIES
This study looks at how the immune system works in people with Food Protein-Induced Enterocolitis Syndrome (FPIES). It aims to learn more about this condition to improve future diagnosis and treatment.
New York, New YorkAges 1–60 - NCT06633250Recruiting
Testing a rice-based formula for babies with cow's milk allergy
This trial tests a special formula made from hydrolyzed rice protein in babies with cow's milk protein allergy. The goal is to see if the formula supports healthy growth and is well-tolerated, while also improving quality of life.
BerlinAges Up to 8 months - NCT05695261RecruitingPhase 2
Oral microbiome capsules for peanut allergy in teens
This Phase 2 study tests whether taking capsules made from donor gut microbes is safe and can reduce allergic reactions to peanuts. It involves peanut allergy testing and close follow-up with stool samples and check-ins.
Boston, MassachusettsAges 12–17 - NCT06602141Recruiting
Exercise and fat cell changes study
This study looks at how endurance exercise changes fat cells in the body. It may help understand how exercise benefits weight-related health.
Orlando, FloridaAges 18–45 - NCT06580197Recruiting
Ear acupuncture after belly surgery to help recovery
This trial looks at whether ear acupuncture can help people recover after major abdominal surgeries like Whipple, pancreatectomy, or subtotal gastrectomy. It may help reduce digestive problems by tracking a substance called AAT (alpha-1 antitrypsin).
Beijing, Beijing MunicipalityAges 40–70
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 155 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.