Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06576401RecruitingPhase 1
HDM1002 metabolism study in healthy Chinese men
This study tests how a new drug called HDM1002 leaves the body, using a tiny amount of a radioactive marker. It's for healthy men, and the results will help researchers understand how the drug works.
Suzhou, JiangsuAges 18–45 - NCT06580197Recruiting
Ear acupuncture after belly surgery to help recovery
This trial looks at whether ear acupuncture can help people recover after major abdominal surgeries like Whipple, pancreatectomy, or subtotal gastrectomy. It may help reduce digestive problems by tracking a substance called AAT (alpha-1 antitrypsin).
Beijing, Beijing MunicipalityAges 40–70 - NCT06827977RecruitingPhase 2
Microbiome transplant for constipation and bloating in scleroderma
This study tests a microbiome transplant (friendly bacteria given as an enema or in capsules) to see if it helps with constipation and bloating in people with scleroderma. The goal is to improve digestive symptoms related to your condition.
Houston, TexasAges 18 years+ - NCT06602141Recruiting
Exercise and fat cell changes study
This study looks at how endurance exercise changes fat cells in the body. It may help understand how exercise benefits weight-related health.
Orlando, FloridaAges 18–45 - NCT06605898Recruiting
Metabolic and lifestyle study for adults 45-64
This study tests a personalized diet and lifestyle program to improve metabolic health. It may help if you are between 45 and 64, do not smoke, and have no major digestive or liver conditions.
Urbana, IllinoisAges 45–64 - NCT06683521Recruiting
Understanding the immune system in FPIES
This study looks at how the immune system works in people with Food Protein-Induced Enterocolitis Syndrome (FPIES). It aims to learn more about this condition to improve future diagnosis and treatment.
New York, New YorkAges 1–60 - NCT06687382RecruitingPhase 2
MBK-01 for recurrent diverticulitis
This trial tests MBK-01, capsules made from healthy gut bacteria, to see if they can help people who keep getting diverticulitis. If you've had three or more bouts in the last three years, this study might offer a new treatment option.
Madrid, MadridAges 18–70 - NCT05791604Recruiting
Study prebiotics and probiotics to help children with Prader-Willi
This trial studies whether taking prebiotics and probiotics can help children with Prader-Willi syndrome manage obesity. It’s testing a gut-focused approach to weight control over the study period.
Shanghai, Shanghai MunicipalityAges 3–10 - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75 - NCT07545772RecruitingPhase 2
Testing Brenipatide for Constipation-Focused IBS
This trial tests a new medicine called brenipatide to see if it can help people with IBS-C (irritable bowel syndrome with constipation). The study focuses on whether the drug reduces belly pain and improves bowel movements in people whose main symptom is hard or infrequent stools.
Mesa, ArizonaAges 18–75 - NCT06727422RecruitingPhase 2
Rifaximin plus NAC for IBS with diarrhea
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT06801938Recruiting
Blue dye test during incontinence surgery to reduce complications
This study tests if using a special blue dye (methylene blue) during surgery to correct stress urinary incontinence helps doctors find and prevent complications. It compares two surgical methods (TVT and TOT) to see which is safer.
IstanbulAges 18–85 - NCT06805903Recruiting
Validating a survey on transanal irrigation adherence
This study tests a new survey to better understand how well people are following their transanal irrigation treatment. If you use this treatment for bowel issues, the researchers want to see if the survey accurately measures your routine.
ParisAges 18 years+ - NCT06822582Recruiting
Pelvic health rehab after breast or gynecologic cancer
This trial tests a pelvic health rehabilitation program for people who have had breast or gynecologic cancer. It aims to help with pelvic floor problems like bladder or bowel issues that can start during or after treatment.
Edmonton, AlbertaAges 18 years+ - NCT06833866RecruitingPhase 1
Testing a natural compound with chemo for advanced colorectal cancer
This trial combines a natural substance called hydroxytyrosol (HT) with standard chemotherapy (5-FU and possibly other drugs) for people with advanced or metastatic colorectal cancer that hasn't been treated yet. The goal is to see if adding HT makes the treatment work better.
Houston, TexasAges 18 years+ - NCT06848192Recruiting
Parkinson's disease case-control study at Westlake University
This study compares people with Parkinson's disease to healthy volunteers, looking at possible links between the gut and Parkinson's. If you have mild to moderate Parkinson's (or are a healthy match), you may help researchers understand what causes the disease.
Hangzhou, ZhejiangAges 50–75 - NCT06869941Recruiting
How gut health and fat tissue are linked in the brain
This study looks at how the bacteria in your gut might affect your fat tissue and brain. You may be able to join if you are scheduled to have surgery to remove fat tissue and are willing to sign a consent form.
Girona, GironaAges 20 years+ - NCT06877078Recruiting
Podcast for constipation before surgery
This study tests if listening to a podcast about preventing constipation before surgery can help people who are having back, shoulder, knee, or hip surgery. If you are scheduled for one of these surgeries, you may be able to take part.
SilkeborgAges 18 years+ - NCT06934941RecruitingPhase 1
Single dose safety study of NM-101 in healthy men
This trial tests a single dose of a new medication (NM-101) in healthy male volunteers to see how the body handles it and if it's safe. It is a phase 1 study that requires you to be in good health and have no major medical conditions.
SeoulAges 18–60 - NCT06951386Recruiting
Can a daily drink improve heart and metabolic health?
This trial tests whether taking a daily drink containing short-chain fatty acids can improve risk factors for metabolic syndrome, like belly fat, high blood sugar, or high blood pressure. It might help if you are at risk but not yet taking medications for these conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT06961149Recruiting
Comparing light vs dye spray for colon polyp detection
This study compares two methods used during colonoscopy to help find polyps in the colon. It tests whether a special light technique (linked-color imaging) or a dye spray (indigo carmine) works better for spotting adenomas, which are growths that can turn into cancer. If you are at higher risk for colorectal adenomas, this trial may help improve detection.
Jinan, ShandongAges 45–85 - NCT06966869Recruiting
Fentanyl patch absorption in ICU patients
This study looks at how well fentanyl patches work in ICU patients who are not stable. It aims to understand if the patch is absorbed properly in these patients.
Tel Aviv, IsraelAges 18–70 - NCT06989177Recruiting
Can a probiotic help with body weight?
This trial tests whether taking a probiotic (a good bacteria supplement) can help with body weight. It is for healthy adults, and also for overweight or obese people who have certain weight-related health issues.
Hangzhou, ZhejiangAges 20–50
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 154 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.