Clinical trials
Constipation clinical trials
Below are recruiting constipation clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04838522Recruiting
Prucalopride for constipation in breastfeeding women
This study looks at whether prucalopride (Motegrity/Resotran) can help constipation symptoms in women who are breastfeeding. It also monitors the breastfeeding infant during the study while you follow sample-collection and interview requirements.
La Jolla, CaliforniaAges 18 years+ - NCT04623359Recruiting
Testing a detailed bowel pressure test for hard-to-treat constipation
This study checks whether a “high-resolution manometry” test (a thin tube measuring bowel muscle pressure) helps doctors understand and manage constipation. It’s for adults with long-lasting constipation that has not improved with standard laxatives, and who meet specific safety and colon-testing criteria.
CaenAges 18 years+ - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+ - NCT07723924RecruitingPhase 2
Plecanatide for constipation in children and teens
This study tests a new medicine called plecanatide for children and teens with functional constipation. It aims to see if it helps improve bowel movements compared to a placebo (a pill with no medicine).
Birmingham, AlabamaAges 6–17 - NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT07732894Recruiting
Exercise and Guided Imagery for Bowel Symptoms After Cancer Surgery
This study tests if combining gentle aerobic exercise with guided imagery (a relaxation technique using your imagination) can help improve bowel control and reduce symptoms after rectal cancer surgery.
IstanbulAges 18–65 - NCT07519915Recruiting
Understanding Nerve Stimulation for Bowel Problems in Children
This research study looks at using sacral neuromodulation—a treatment that uses mild electrical stimulation of nerves in the lower spine—to help children with bowel movement problems. Researchers want to understand how well this treatment works and what improvements matter most to patients and families.
ErlangenAges 3–18 - NCT07444008Recruiting
BioAmicus Complete for infant digestive and skin issues
This study tests if BioAmicus Complete, a probiotic blend, can help babies with colic, reflux, diarrhea or constipation, and food allergy-related skin problems. Eligible babies are 1 to 4.5 months old, breastfed or formula-fed, and whose parents speak Russian.
Saint PetersburgAges 1 month–5 months - NCT06460038RecruitingPhase 2
Medication study for constipation in Parkinson's
This study tests whether a medication called tenapanor can help relieve constipation in people with Parkinson's disease. If you have Parkinson's and have been struggling with constipation for at least 6 months, this trial may offer a new option to improve bowel regularity.
Waterloo, IowaAges 50–89 - NCT06822582Recruiting
Pelvic health rehab after breast or gynecologic cancer
This trial tests a pelvic health rehabilitation program for people who have had breast or gynecologic cancer. It aims to help with pelvic floor problems like bladder or bowel issues that can start during or after treatment.
Edmonton, AlbertaAges 18 years+ - NCT07388264Recruiting
Probiotic for bloating and gut health
This study tests a probiotic (a good bacteria) called Weizmannia coagulans to see if it helps reduce bloating and improves gut health. Researchers will check how your digestion changes by looking at your stool and gut bacteria.
Saint Charles, MissouriAges 18–50 - NCT06847919Recruiting
Probiotic yogurt for chronic constipation
This study tests whether eating a special probiotic yogurt can help relieve chronic constipation. It may be a simple, natural addition to your diet with minimal side effects.
Suzhou, JiangsuAges 18–65 - NCT07339865Enrolling by invitation
Bladder symptoms study for teens moving to adult care
This study looks at how bladder problems, like frequent urination or leaks, affect teenagers and young adults as they switch from pediatric to adult doctors. The goal is to learn what helps you feel better and manage your health.
Ghent, East-FlandersAges 16–25 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT06031025Recruiting
Study of tummy problems in at-risk infants
This study looks at how common stomach and gut issues are in babies who were born early or had problems at birth, and how these issues change over time.
RomaAges 3 months–2 years - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT06388863Recruiting
Fecal transplant for constipation in Parkinson's disease
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help relieve constipation in people with Parkinson's disease. FMT uses healthy donor stool to improve gut bacteria, which may ease constipation and possibly improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT07225803Recruiting
Managing pelvic floor muscle problems that cause constipation
This study tests a treatment for a specific type of constipation caused by pelvic floor muscles not working together properly (dyssynergic defecation). It aims to help people who strain or feel blocked when trying to have a bowel movement.
Rochester, MinnesotaAges 18–80 - NCT07148583Recruiting
BioAmicus Complete for tummy troubles in babies
This study tests if a probiotic supplement called BioAmicus Complete can help babies with common digestive issues like colic, reflux, constipation, or loose stools. It might be a good option if your baby has these symptoms and you haven't used other probiotics or antibiotics recently.
Haiphong, Hai PhongAges birth–2 years - NCT06777758RecruitingPhase 4
Comparing two sedatives for endoscopy procedures
This trial compares two sedative medications, Remimazolam and Propofol, to see which works better for upper GI endoscopy exams and treatments. The goal is to help doctors choose the best option for patients.
Kaohsiung CityAges 20–80 - NCT07135362Recruiting
Probiotic for improving constipation in adults
This trial tests a probiotic supplement to see if it helps improve bowel function in people with constipation. If you have functional constipation (not caused by another illness), this study may be a good fit.
TaipeiAges 18–65 - NCT07103772Enrolling by invitation
Does a food supplement help irritable bowel syndrome?
This study tests a special food-based supplement (called a nutraceutical) to see if it helps relieve symptoms of irritable bowel syndrome (IBS), like diarrhea and constipation. It is only open to UANL employees and their beneficiaries who are not already on medication for their stomach issues.
Monterrey, Nuevo LeónAges 18 years+
Hear when a new Constipation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for constipation?
- Yes. Clin2 currently lists 90 recruiting constipation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.