Clinical trials
Constipation clinical trials
Below are recruiting constipation clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT07344402Recruiting
Optimizing ear stimulation for chronic constipation
This study tests whether mild electrical stimulation on the ear (called taVNS) can help people with difficult-to-treat constipation. It aims to find the best stimulation schedule to improve bowel movements.
Xi'anAges Any age - NCT07300423Recruiting
Parent views on physical activity in kids with constipation
This study asks parents of children with constipation to share their views on their child's physical activity. It aims to understand how physical activity relates to constipation in children.
AlingsåsAges 18 years+ - NCT07275866Recruiting
Probiotic study for people with constipation
This study tests whether a multi-strain probiotic can help relieve constipation. You would stop other constipation treatments and track your symptoms with a daily diary.
LondonAges 18–70 - NCT07277907RecruitingPhase 3
Lubiprostone for slow-transit constipation in adults
This study tests whether lubiprostone (Amitiza) can help people with slow-transit constipation. If you have few bowel movements and tests show that stool moves slowly through your colon, this treatment may help you go more regularly.
Bishan, Chongqing MunicipalityAges 18 years+ - NCT07276932Recruiting
Acupoint paste for constipation after chemo
This study tests whether applying a special paste to acupoints (specific points on your body) can help relieve constipation and boost energy (qi) in people with colorectal cancer who've had chemotherapy. It's for patients who feel weak and have trouble with constipation after treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT07231796Recruiting
Study of naldemedine for opioid-induced constipation in cancer patients
This trial tests whether naldemedine, a medication for constipation, can help cancer patients who have constipation caused by opioids. It looks at how well it works and how patients feel.
AmsterdamAges 18 years+ - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07202481Recruiting
Fiber supplements for constipation in women
This trial tests if two types of fiber—one from chicory and one from a plant husk—can help women with constipation move food through their intestines faster. It aims to find a gentle, non-drug option that might work better than what you eat now.
Belo Horizonte, Minas GeraisAges 18–59 - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT06959758RecruitingPhase 4
Probiotics for childhood constipation
This study tests whether a probiotic supplement (BioKid LR) can help children with functional constipation — a condition where a child has hard, infrequent bowel movements with no other medical cause. The probiotic contains nine different types of good bacteria, including L. reuteri.
AfulaAges 6 months–17 years - NCT07082673Recruiting
Sea buckthorn supplement for chronic constipation
This study tests a food supplement made from sea buckthorn to see if it helps people with chronic constipation have more regular and comfortable bowel movements.
NaplesAges 18–70 - NCT07083596Recruiting
Fermented milk drink for constipation relief in Filipino adults
This study tests if a special fermented milk drink can help relieve constipation symptoms like hard or lumpy stools. Researchers want to see if it works for adults who have constipation without a known medical cause.
Manila, ManilaAges 18–59 - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT06911749Recruiting
Using MSOT and MRI to measure bowel transit in children
This trial tests whether two imaging techniques, MSOT and MRI, can safely and non-invasively measure how long it takes for food to move through the bowels in children with chronic constipation or other bowel emptying problems. It may help doctors better understand and treat these conditions.
Erlangen, BavariaAges 1 year+ - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT06833684Recruiting
Comparing MOWOOT and trans-anal irrigation for constipation
This study tests two treatments for chronic constipation: a device called MOWOOT (which uses gentle abdominal massage) and trans-anal irrigation (a way to wash out the rectum). It is for people who have tried biofeedback therapy and still need help managing their constipation.
London, LondonAges 18 years+ - NCT06827977RecruitingPhase 2
Microbiome transplant for constipation and bloating in scleroderma
This study tests a microbiome transplant (friendly bacteria given as an enema or in capsules) to see if it helps with constipation and bloating in people with scleroderma. The goal is to improve digestive symptoms related to your condition.
Houston, TexasAges 18 years+ - NCT06738550Enrolling by invitation
Agave inulin for constipation in new dialysis patients
This study tests whether a natural fiber supplement called agave inulin can help with constipation and improve quality of life for people who have just started peritoneal dialysis for kidney failure.
Metepec, State of MexicoAges 18 years+ - NCT06413368RecruitingPhase 2/Phase 3
Maralixibat for cystic fibrosis constipation
This trial tests a medicine called maralixibat to see if it helps children with cystic fibrosis who have chronic constipation that doesn't improve with standard treatments. The goal is to improve bowel movements and quality of life.
Los Angeles, CaliforniaAges 1–18 - NCT06357897Recruiting
New PEG formula for children with functional constipation
This trial tests a new, better-tasting liquid formula (PEG-based) for children with functional constipation. It aims to see if it works as well as or better than current treatments and if children like the taste more.
BangkokAges 6 months–18 years - NCT04903470Recruiting
Study bowel movement patterns in constipation and healthy adults
This study compares bowel movement patterns in people with chronic constipation versus people without constipation. It may help researchers better understand what’s happening in constipation to guide future care and treatments.
San Diego, CaliforniaAges 21–75 - NCT05603715RecruitingPhase 2
Pyridostigmine to help constipation in Parkinson’s
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Burlington, VermontAges 18 years+ - NCT05216328RecruitingPhase 4
Preventing opioid-related constipation in advanced cancer
This trial tests whether starting a laxative right away can prevent constipation caused by pain medications called opioids. It's for people with advanced cancer who are beginning opioid pain treatment and aims to improve comfort and quality of life.
Almere Stad, FlevolandAges 18 years+
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Common questions
- Are there clinical trials for constipation?
- Yes. Clin2 currently lists 90 recruiting constipation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.