Clinical trials
Constipation clinical trials
Below are recruiting constipation clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07300423Recruiting
Parent views on physical activity in kids with constipation
This study asks parents of children with constipation to share their views on their child's physical activity. It aims to understand how physical activity relates to constipation in children.
AlingsåsAges 18 years+ - NCT07275866Recruiting
Probiotic study for people with constipation
This study tests whether a multi-strain probiotic can help relieve constipation. You would stop other constipation treatments and track your symptoms with a daily diary.
LondonAges 18–70 - NCT07506122Recruiting
Acupuncture for chronic constipation: dose study
This trial tests different amounts of acupuncture to see which dose works best for chronic constipation. It may help if you have had constipation for at least 6 months and have fewer than 2 complete bowel movements per week without using laxatives.
Wuhan, HubeiAges 18–75 - NCT06526767Recruiting
Vibrating capsule for chronic constipation dose comparison
This study tests three different doses of a vibrating capsule (Vibrabot) to see which works best for relieving chronic constipation. If you have had constipation for at least 6 months and meet the Rome IV criteria, you may be able to join.
Beijing, Beijing MunicipalityAges 18–85 - NCT06802042Recruiting
Probiotic for constipation in pregnancy
This trial tests if a probiotic called Lactobacillus can help relieve constipation in pregnant women and improve gut health. It compares the probiotic to a placebo to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–40 - NCT07202481Recruiting
Fiber supplements for constipation in women
This trial tests if two types of fiber—one from chicory and one from a plant husk—can help women with constipation move food through their intestines faster. It aims to find a gentle, non-drug option that might work better than what you eat now.
Belo Horizonte, Minas GeraisAges 18–59 - NCT06543979RecruitingPhase 1/Phase 2
Anorectal manometry for children with chronic constipation
This study is for children aged 4–16 who have long-term constipation that doesn't get better with standard laxatives. It uses a test called anorectal manometry to measure how well the muscles in the bottom work, which can help guide treatment.
CairoAges 4–16 - NCT06738550Enrolling by invitation
Agave inulin for constipation in new dialysis patients
This study tests whether a natural fiber supplement called agave inulin can help with constipation and improve quality of life for people who have just started peritoneal dialysis for kidney failure.
Metepec, State of MexicoAges 18 years+ - NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT07276932Recruiting
Acupoint paste for constipation after chemo
This study tests whether applying a special paste to acupoints (specific points on your body) can help relieve constipation and boost energy (qi) in people with colorectal cancer who've had chemotherapy. It's for patients who feel weak and have trouble with constipation after treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT06833684Recruiting
Comparing MOWOOT and trans-anal irrigation for constipation
This study tests two treatments for chronic constipation: a device called MOWOOT (which uses gentle abdominal massage) and trans-anal irrigation (a way to wash out the rectum). It is for people who have tried biofeedback therapy and still need help managing their constipation.
London, LondonAges 18 years+ - NCT07382167RecruitingPhase 3
Study of Tenapanor for Chronic Constipation in Adults
This study tests an investigational drug called tenapanor for people with chronic idiopathic constipation (constipation with no clear cause). It aims to see if the drug can safely improve bowel movements in adults.
Foley, AlabamaAges 18–80 - NCT06959758RecruitingPhase 4
Probiotics for childhood constipation
This study tests whether a probiotic supplement (BioKid LR) can help children with functional constipation — a condition where a child has hard, infrequent bowel movements with no other medical cause. The probiotic contains nine different types of good bacteria, including L. reuteri.
AfulaAges 6 months–17 years - NCT06106685RecruitingPhase 1/Phase 2
Washed microbiota transplant for chronic constipation
This trial tests a treatment called washed microbiota transplantation (a procedure that delivers healthy gut bacteria to your colon) for adults with chronic constipation. The goal is to see if it can improve bowel movements without the need for laxatives.
Nanjing, JiangsuAges 18–70 - NCT07277907RecruitingPhase 3
Lubiprostone for slow-transit constipation in adults
This study tests whether lubiprostone (Amitiza) can help people with slow-transit constipation. If you have few bowel movements and tests show that stool moves slowly through your colon, this treatment may help you go more regularly.
Bishan, Chongqing MunicipalityAges 18 years+ - NCT07077044Recruiting
Testing nerve stimulation for kids with constipation
This study tests a new treatment for children with long-lasting constipation that hasn't improved with standard care. It compares nerve stimulation (TTNS with or without a special device called PHUS) against usual therapy to see which works best.
JerusalemAges 4–14 - NCT07705542Recruiting
Balloon use during biofeedback for constipation
This study tests whether using a balloon during biofeedback therapy helps people with constipation caused by pelvic floor dysfunction. It's for people who have trouble relaxing their pelvic floor muscles during bowel movements.
HullAges 18 years+ - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+ - NCT03819062Recruiting
Stomach–bowel nerve stimulation for long-term constipation
This trial studies a device that stimulates nerves near the lower back (sacrum) to improve bowel function in people with severe constipation that hasn’t responded to standard treatments. It may help if your constipation involves problems coordinating bowel movement and the muscles around the rectum.
Hamilton, OntarioAges 6–70 - NCT05216328RecruitingPhase 4
Prevent constipation in people with advanced cancer on opioids
This study tests whether starting a bowel-prevention approach can help stop constipation caused by opioid pain medicines in people with advanced (metastatic) cancer. You may be able to join if you are about to start long-acting or skin opioid pain treatment.
Almere Stad, FlevolandAges 18 years+ - NCT05603715RecruitingPhase 2
Pyridostigmine to help constipation in Parkinson’s
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Burlington, VermontAges 18 years+ - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT06390761Recruiting
Acupuncture for constipation in Parkinson's disease
This trial tests whether acupuncture can help relieve constipation in people with Parkinson's disease. If you have both Parkinson's and constipation that is not caused by another medical condition, this study may offer a non-drug treatment option.
Xi'an, ShaanxiAges 35–80 - NCT06413368RecruitingPhase 2/Phase 3
Maralixibat for cystic fibrosis constipation
This trial tests a medicine called maralixibat to see if it helps children with cystic fibrosis who have chronic constipation that doesn't improve with standard treatments. The goal is to improve bowel movements and quality of life.
Los Angeles, CaliforniaAges 1–18
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Common questions
- Are there clinical trials for constipation?
- Yes. Clin2 currently lists 99 recruiting constipation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.