Clinical trials
Constipation clinical trials
Below are recruiting constipation clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06755671Recruiting
Danning tablets for digestive symptom relief
This study looks at how well Danning tablets work for people with upset stomach, bloating, heartburn, or constipation. It follows patients who are already taking the tablets as part of their regular care.
Hangzhou, ZhejiangAges 18–75 - NCT06825260RecruitingPhase 4
PEG3350 vs Senna after urogynecologic surgery
This study compares two common laxatives to see which works better for preventing constipation after surgery for pelvic organ prolapse or stress urinary incontinence. It will help find the best way to keep you comfortable during recovery.
Syracuse, New YorkAges 18 years+ - NCT05805436RecruitingPhase 4
Laxatives before robotic prostate or kidney surgery
This trial tests whether giving a laxative before certain robotic urologic surgeries improves bowel function after surgery. It may help reduce constipation and related discomfort during recovery.
Iowa City, IowaAges 30–100 - NCT06837064Enrolling by invitation
Can a chatbot help manage Irritable Bowel Syndrome?
This study tests whether a chatbot can help adults with Irritable Bowel Syndrome (IBS) manage their symptoms. If you have been diagnosed with IBS, you may be able to join and use the chatbot as part of your care.
MoscowAges 18 years+ - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT04547816RecruitingPhase 3
Non-surgical treatment for constipation-related prolapse in women
This study tests whether a non-surgical (“conservative”) approach can improve constipation-related bowel problems in women who have a mild-to-moderate rectal bulge from pelvic organ prolapse. It may help by addressing how the rectum and pelvic floor work during bowel movements.
MoscowAges 18–70 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT06335797Recruiting
Improving bowel habits after pelvic surgery
This study looks at ways to improve bowel habits after vaginal surgery for pelvic organ prolapse. It aims to find better routines to help you recover comfortably.
Winston-Salem, North CarolinaAges 18 years+ - NCT06273046Recruiting
Biofeedback for bowel control problems
This trial tests a non-invasive biofeedback technique to help people regain control of bowel movements. It may be an option for those with frequent stool leakage or difficult constipation, but participants must not have certain other digestive or neurological conditions.
BarcelonaAges 18–75 - NCT05807321Recruiting
Biofeedback therapy for bowel coordination problems
This trial tests a biofeedback therapy program (training using feedback to improve bowel movements) for people with bowel coordination problems called dyssynergia. It may help you learn techniques that make passing stool easier and more predictable.
San Diego, CaliforniaAges 21–75 - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Foley, AlabamaAges 6–18 - NCT05821309RecruitingPhase 4
Testing how a new enema routine changes gut bacteria
This study looks at how placing an antegrade (forward-flow) continence enema and starting a bowel flush routine may change your gut microbiome (your gut bacteria). It is meant for children who have long-lasting constipation that required a special surgical drainage channel.
Carmel, IndianaAges 2–18 - NCT05796388Recruiting
Virtual reality and linaclotide for IBS with constipation
This study tests whether virtual reality (VR) plus linaclotide can improve symptoms and quality of life in adults with IBS-C (IBS with constipation). You may be asked to use VR and take a study medicine, while doctors check that your IBS diagnosis fits strict criteria.
Jacksonville, FloridaAges 18–70 - NCT05588323RecruitingPhase 1/Phase 2
Testing naldemedine for constipation caused by opioid pain meds
This study tests whether naldemedine is safe and how the body processes it in children who take opioid medicines and are dealing with constipation or are at risk for it. It may help some children by reducing constipation side effects from opioid pain treatment.
TiranaAges 2–18 - NCT05519683RecruitingPhase 2/Phase 3
Home electrical stimulation for constipation IBS pain
This trial tests whether a home device that uses mild skin electrical stimulation can reduce belly pain from IBS with constipation. It also checks whether the treatment is safe and helpful for symptom relief over the study period.
Ann Arbor, MichiganAges 18 years+ - NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT03842007Recruiting
Study of constipation symptoms and how bowel function works
This study looks at how normal bowel movements work, and what goes wrong in people with long-term constipation. It may help researchers better understand constipation causes, which can guide future treatments.
Rochester, MinnesotaAges 18–80
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Common questions
- Are there clinical trials for constipation?
- Yes. Clin2 currently lists 90 recruiting constipation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.