Clinical trials · Florida
Coronary artery disease clinical trials in Florida
We’re tracking 39 recruiting coronary artery disease studies with a site in Florida — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Coral Gables, FloridaAges 18–80 - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Boca Raton, FloridaAges 18–80 - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Clearwater, FloridaAges 18–110 - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Pensacola, FloridaAges 18 years+ - NCT07025148RecruitingPhase 4
Comparing two blood thinners after stenting for high-risk patients
This trial tests switching from a standard blood thinner (clopidogrel) to a lower dose of a stronger one (prasugrel) in people who have had a stent placed and are at high risk for both bleeding and heart problems. The goal is to see if the switch better prevents clots while keeping bleeding risks low.
Jacksonville, FloridaAges 18 years+ - NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
Gainesville, FloridaAges 18 years+ - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Boca Raton, FloridaAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Atlantis, FloridaAges Any age - NCT06686121RecruitingPhase 3
Walking recovery after leg artery treatment
This study tests whether a home-based exercise program or a special beetroot drink can help people walk better after having a procedure to improve blood flow in their legs. It aims to find ways to boost mobility and quality of life.
Tampa, FloridaAges 18 years+ - NCT06625801Recruiting
IVUS-guided heart procedure registry for minority patients
This study is collecting information from heart procedures that use IVUS (a special ultrasound inside the blood vessels) to treat complex blockages. It aims to learn how well these procedures work in patients who identify as a racial or ethnic minority.
Orlando, FloridaAges 18 years+ - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Tallahassee, FloridaAges 18–80 - NCT06228456RecruitingPhase 4
Low-dose ticagrelor vs clopidogrel for stable heart patients after stent
This trial tests whether a lower dose of the blood thinner ticagrelor works better than clopidogrel in people with stable coronary artery disease who are getting a planned stent. It aims to find which drug is safer and more effective for preventing future heart problems.
Jacksonville, FloridaAges 18 years+ - NCT06164730RecruitingPhase 1
Study of VERVE-102 for high cholesterol or early heart disease
This trial tests a new medicine called VERVE-102 for people with a specific type of high cholesterol (HeFH) or early coronary artery disease. It aims to see if it can help lower cholesterol levels.
Boca Raton, FloridaAges 18–70 - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Hollywood, FloridaAges 18 years+ - NCT07318610RecruitingPhase 3
Study of a new blood thinner in people with leg artery disease
This trial tests if a new blood-thinning drug (factor XI inhibitor) can prevent serious heart and leg problems in people who recently had a leg artery procedure. It compares the new drug to standard care for up to 3 years.
Crystal River, FloridaAges 18 years+ - NCT07223593RecruitingPhase 3
Orforglipron for peripheral artery disease with leg pain
This trial tests a new oral medication called orforglipron to see if it can improve walking distance in people with peripheral artery disease (PAD) who have leg pain when walking. It may be a good option if you have PAD and your walking is limited by leg cramping, not other health issues.
Leesburg, FloridaAges 18 years+ - NCT07559903Recruiting
Drug-coated balloon heart artery treatment registry
This study tracks outcomes in adults who receive a special balloon catheter (coated with medication) to open blocked heart arteries. Researchers collect data to understand how well this treatment works and any side effects that occur.
Fort Lauderdale, FloridaAges 18 years+ - NCT07225842RecruitingPhase 4
Bridging with Cangrelor: A study on pre-procedure blood thinner use
This study looks at how well a certain blood thinner (cangrelor) works when used as a 'bridge' before surgery or another procedure. It is for people who already need to be on this medicine for a short time.
Jacksonville, FloridaAges 18 years+ - NCT06445608Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a temporary heart pump (called the KARDION Cory P4) used during a high-risk angioplasty (stenting) procedure. The pump helps keep blood flowing in patients whose heart is weak or who have complex blockages, aiming to make the procedure safer.
Jacksonville, FloridaAges 18–90 - NCT06821191RecruitingPhase 4
Safer blood thinner plan after heart stent
This trial is testing whether lowering the dose of your current blood thinner or switching to a different one (clopidogrel) is safer and works just as well after you've had a stent placed. It's designed for people who are already on two blood thinners and are doing well.
Jacksonville, FloridaAges 18 years+ - NCT06691191RecruitingPhase 4
Switching to a single blood thinner after heart stent
This trial tests if people who have been on two blood thinners (aspirin plus prasugrel or ticagrelor) for at least 90 days after getting a heart stent can safely switch to just one of those blood thinners. It aims to see if taking only one pill is as safe and effective as taking two.
Jacksonville, FloridaAges 18–75 - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
Gainesville, FloridaAges 18 years+ - NCT06588595RecruitingPhase 4
Switching Blood Thinners After Stent Placement
This study compares two ways to manage blood thinners after a stent. It tests whether switching from stronger drugs (prasugrel or ticagrelor) to clopidogrel is safe and effective for long-term heart protection.
Jacksonville, FloridaAges 18 years+
Coronary artery disease trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting coronary artery disease studies listed above.
- University of Florida Jacksonville · 3 studies
- Clearwater Cardiovascular and Interventional Consultants · 2 studies
- Tampa General Hospital / University of South Florida · 2 studies
- The Cardiac and Vascular Institute · 2 studies
- University of Florida · 2 studies
- Abcentra Investigational Site
- Advent Health
- AdventHealth
What taking part in a coronary artery disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Coronary artery disease trials in other states
Common questions
- Are there coronary artery disease clinical trials in Florida?
- Yes. We're currently tracking 39 recruiting coronary artery disease studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a coronary artery disease study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New coronary artery disease studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.