Clinical trials
Coughing clinical trials
Below are recruiting coughing clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06600646Recruiting
Study of energy production in airway cells for chronic cough
This study looks at how the cells lining your airways make energy and whether this is different in people with chronic cough that doesn't get better with treatment or has no clear cause. It may help doctors understand why some people cough and find new ways to treat it.
Hamilton, OntarioAges 18–80 - NCT07103980RecruitingPhase 1/Phase 2
Study of stem cell particles for cough after infection
This trial tests if inhaled particles from stem cells (called exosomes) can help with a cough that lasts 3-8 weeks after a cold or flu. It may be an option if your chest X-ray is normal and other causes of cough have been ruled out.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07085975RecruitingPhase 1
Safety of inhaled ATP cough challenges
This study tests how safe and repeatable an inhaled ATP cough challenge is. It first enrolls healthy adults, then people with chronic cough or mild asthma who have not used steroid inhalers recently.
Hamilton, OntarioAges 18 years+ - NCT06979141RecruitingPhase 3
Cough prevention after general anesthesia
This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.
AsyutAges 21–60 - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT06669897Recruiting
Cough severity questionnaire study
This study is testing a new questionnaire to measure how severe a cough is. It is looking for people with a chronic cough (cough lasting a long time) and healthy volunteers to see if the questionnaire works well.
Badalona, BarcelonaAges 30–99 - NCT06548711Recruiting
Acupoint stimulation for cough after lung cancer surgery
This trial tests if a gentle electrical stimulation on your skin at specific points (acupoints) can help reduce a dry cough that lasts 2 weeks or more after lung cancer surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT05665244Recruiting
Cryotherapy for long-lasting cough from nerve signals
This trial tests a cold-treatment procedure (cryotherapy) to treat a stubborn cough caused by nerve signaling (not infections or common allergy/acid problems). It may help people whose cough has lasted at least 8 weeks and who have already tried to rule out other causes.
Dallas, TexasAges 18 years+ - NCT05317247Recruiting
Cough sound test to quickly triage possible tuberculosis
This trial checks whether listening to your cough on an audio recording can help triage—meaning sort—people who may have tuberculosis (TB). If you have had a cough for at least two weeks, the study may help doctors decide who needs further TB testing.
Cape Town, Western CapeAges 12 years+ - NCT05273190Recruiting
Using gentle larynx stimulation to treat chronic unexplained cough
This study tests whether stimulating the larynx (voice box area) can reduce cough that has lasted more than 8 weeks. It may help people whose cough is not clearly explained by infections, lung diseases, or other common causes.
Minneapolis, MinnesotaAges 18–88 - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT04642352Recruiting
Nerve block injections for long-lasting nerve cough
This trial studies an office-based injection to calm a specific nerve in the neck to treat chronic cough that seems to come from nerve irritation (“neurogenic/sensory neuropathic” cough). It may help people whose cough has lasted at least 8 weeks and continues despite standard treatments for common cough causes.
Birmingham, AlabamaAges 18 years+ - NCT05989802Recruiting
Testing new TB tests for children
This study is testing new ways to quickly diagnose TB in children under 15. It aims to find better tests that can be used at clinics, especially for kids who may not have obvious symptoms.
MaputoAges Up to 65 years - NCT04807712Recruiting
Testing a pertussis workup for children at home visits
This trial studies children who might have pertussis (“whooping cough”). It looks at children in outpatient/home-care settings when the child’s doctor suspects pertussis and orders a lab test, to help guide evaluation and care.
CréteilAges 1 day–18 years - NCT07857356RecruitingPhase 4
Pain relief during breathing tube removal after thyroid surgery
This study compares two medicines given while the breathing tube is removed after thyroid surgery. It aims to reduce coughing and discomfort, making recovery more comfortable.
DenizliAges 18–65 - NCT07868419RecruitingPhase 3
Nalbuphine tablets for chronic cough in pulmonary fibrosis
This trial tests an extended-release tablet called nalbuphine to reduce chronic coughing in people with idiopathic pulmonary fibrosis (IPF), a lung condition that causes scarring and often leads to a persistent cough. If you have IPF and have been coughing for at least 8 weeks, this study may help manage that symptom.
Wilmington, DelawareAges 40 years+ - NCT05897879Recruiting
Study how pertussis germs and immune response affect severity
This study looks at children with suspected pertussis (who need a PCR test) and compares how the bacteria and the immune response relate to how sick they become. It may help doctors understand why some children have worse symptoms and guide future care.
BordeauxAges Up to 15 years - NCT06476249Recruiting
Cough risk after lung surgery via thoracoscope
This study looks at why some people develop a cough after having part of a lung removed through small cuts (video-assisted thoracoscopic surgery). It may help identify who is more likely to have this side effect.
Kunming, YunnanAges 18–70 - NCT07709390RecruitingEarly Phase 1
Lidocaine gel on breathing tube for surgery
This trial tests whether putting lidocaine gel on the breathing tube before surgery can reduce post-operative sore throat and coughing. It aims to make recovery more comfortable for patients having general anesthesia.
Columbus, OhioAges 18–90 - NCT07678086Recruiting
Breathing tube pressure and sore throat in children's appendix surgery
This trial tests whether carefully managing the pressure in the breathing tube during surgery can help prevent a sore throat in children after they have their appendix removed by keyhole surgery. It may help your child have a more comfortable recovery.
Ankara, YenimahalleAges 6–18 - NCT07671911RecruitingPhase 3
Cough relief for pulmonary fibrosis
This trial tests a new extended-release medicine, nalbuphine, to reduce chronic coughing in people with idiopathic pulmonary fibrosis (a lung disease that scars the lungs). It may help make cough less frequent and less bothersome.
Newport Beach, CaliforniaAges 40 years+ - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT06542484Recruiting
Studying gefapixant for cough in kidney or bladder cancer
This study tests a medicine called gefapixant to see if it helps reduce chronic coughing in people with kidney or bladder cancer. You may qualify if your cough persists despite treatment and you have little to no smoking history.
Nagoya, Aichi-kenAges 18 years+ - NCT07420946Recruiting
Expert opinions on a lung clearance device for ICU patients
This study gathers expert opinions from healthcare professionals about using a device called MI-E to help clear airways in critically ill patients. If you are a clinician with experience in this area, your input could help shape future guidelines.
NaplesAges Any age
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Common questions
- Are there clinical trials for coughing?
- Yes. Clin2 currently lists 69 recruiting coughing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coughing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coughing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.