Clinical trials
Coughing clinical trials
Below are recruiting coughing clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT07070895Recruiting
Wellness app for chronic cough study
This trial tests a smartphone app and a smartwatch to help people with chronic cough that hasn't improved with standard care. You'll wear a watch to track your cough and use the app to learn management techniques.
Wilmington, DelawareAges 21 years+ - NCT06960759RecruitingPhase 2
Cough suppression therapy for chronic cough
This study tests a behavior-based therapy to help you gain control over a persistent cough that hasn't responded to other treatments. You will learn techniques to reduce coughing during a 4-week program.
Aurora, ColoradoAges 18–99 - NCT06878209Recruiting
Cough and hemorrhoids study
This study looks at how coughing may relate to hemorrhoids. Researchers want to understand the possible connection in people who have hemorrhoids but haven't had surgery for them.
Muğla, MenteşeAges 18 years+ - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT04767074Recruiting
Non-drug therapy to reduce long-term cough in lung scarring
This study tests a non-medication cough-control program for people who have lung scarring (interstitial lung disease) and a cough lasting more than 8 weeks. It may help you control coughing better without adding new medicines.
Hamilton, OntarioAges 18–85 - NCT05813223RecruitingEarly Phase 1
Gefapixant to study brain activity in chronic cough
This early study tests whether gefapixant changes brain activity related to cough in people with chronic cough that hasn’t improved with usual treatments. It may help researchers understand why chronic cough happens and how to better treat it.
Parkville, VictoriaAges 18–65 - NCT06376448Recruiting
Chronic cough study using a new questionnaire
This study aims to better understand different types of chronic cough by using a new questionnaire. If you have had a cough for at least 8 weeks and do not smoke, you may be able to help.
Cottingham, East YorkshiureAges 18 years+ - NCT07683780Enrolling by invitation
Spinal stimulation and muscle training for cough after spinal cord injury
This study tests a combination of spinal cord stimulation and electrical muscle stimulation to help improve cough strength in people with a recent spinal cord injury. It may help you clear secretions more effectively.
Chicago, IllinoisAges 18–65 - NCT06918756Recruiting
Cough control questionnaire development study
This study is creating a new questionnaire to measure how well people can control their cough. It includes people with different types of cough and a small number of healthy volunteers.
LondonAges 18–100 - NCT07103980RecruitingPhase 1/Phase 2
Study of stem cell particles for cough after infection
This trial tests if inhaled particles from stem cells (called exosomes) can help with a cough that lasts 3-8 weeks after a cold or flu. It may be an option if your chest X-ray is normal and other causes of cough have been ruled out.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07722260Recruiting
Cough assistance for breathing tube weaning
This study tests whether special cough-aid techniques help adults on breathing tubes get off the ventilator faster. It may be an option for patients who need extra help coughing while they recover.
DamanhūrAges 18 years+ - NCT05665244Recruiting
Cryotherapy for long-lasting cough from nerve signals
This trial tests a cold-treatment procedure (cryotherapy) to treat a stubborn cough caused by nerve signaling (not infections or common allergy/acid problems). It may help people whose cough has lasted at least 8 weeks and who have already tried to rule out other causes.
Dallas, TexasAges 18 years+ - NCT06587126Recruiting
Can a Cough Monitor Work in Children?
This study tests a way to monitor coughing in children at home, including children with cystic fibrosis and healthy children. It will help researchers learn how well a cough monitor works in real life.
Aurora, ColoradoAges 1–18 - NCT07531901Recruiting
Testing Cough Sensitivity With a Handheld Inhaler Device
This study tests whether a handheld nebulizer (a device that turns liquid medicine into mist) can reliably measure how sensitive your cough reflex is. Researchers will have you inhale citric acid (a harmless substance similar to lemon juice) and record your cough response to see if this method works well.
Missoula, MontanaAges 18–89 - NCT07660380RecruitingPhase 4
Comparing Two Painkillers for Cough During Anesthesia
This study compares a new painkiller (oliceridine) to a standard one (sufentanil) to see which works better at stopping coughing when you first go under anesthesia for surgery. It may help you have a smoother start to your procedure.
Tianmen, HubeiAges 18–99 - NCT04642352Recruiting
Nerve block injections for long-lasting nerve cough
This trial studies an office-based injection to calm a specific nerve in the neck to treat chronic cough that seems to come from nerve irritation (“neurogenic/sensory neuropathic” cough). It may help people whose cough has lasted at least 8 weeks and continues despite standard treatments for common cough causes.
Birmingham, AlabamaAges 18 years+ - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT05273190Recruiting
Using gentle larynx stimulation to treat chronic unexplained cough
This study tests whether stimulating the larynx (voice box area) can reduce cough that has lasted more than 8 weeks. It may help people whose cough is not clearly explained by infections, lung diseases, or other common causes.
Minneapolis, MinnesotaAges 18–88 - NCT05317247Recruiting
Cough sound test to quickly triage possible tuberculosis
This trial checks whether listening to your cough on an audio recording can help triage—meaning sort—people who may have tuberculosis (TB). If you have had a cough for at least two weeks, the study may help doctors decide who needs further TB testing.
Cape Town, Western CapeAges 12 years+ - NCT06286163Recruiting
ATP and P2X3 in chronic cough patients
This study looks at how certain nerve receptors (called P2X3) and a molecule called ATP might be linked to inflammation in the airways of people with chronic cough. It compares chronic cough patients to healthy non-smokers to better understand the cause of cough and find new treatment targets.
LondonAges 30–70 - NCT06481540Recruiting
Smartphone app for cough training in Parkinson's
This trial tests a smartphone app called SpiroGym to help people with Parkinson's disease improve their cough strength. It aims to see if app-guided exercises can make coughing more effective for clearing the airway.
PragueAges 40–80 - NCT06500949Recruiting
Vagus nerve block to reduce cough after lung surgery
This study tests whether blocking a specific nerve in the lung can reduce coughing after having a lung tumor removed through a small camera (VATS surgery). If you're having this surgery and are generally healthy, you may be able to join.
Hangzhou, ZhejiangAges 18–70
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Common questions
- Are there clinical trials for coughing?
- Yes. Clin2 currently lists 73 recruiting coughing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coughing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coughing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.