Clinical trials
Dementia clinical trials
Below are recruiting dementia clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06949865Recruiting
AI-enhanced levodopa challenge test for parkinsonism
This study uses artificial intelligence (AI) to improve a standard test for parkinsonism called the levodopa challenge test. It may help doctors better understand how your movement symptoms respond to levodopa, a common Parkinson's medication.
BeijingAges 50–75 - NCT06933095Recruiting
DHA supplement study for older adults with mild memory concerns
This study tests whether a DHA (omega-3) supplement can improve delivery of certain brain fats in older adults who have mild memory concerns. It involves taking a daily supplement and may include a lumbar puncture (spinal tap).
Cincinnati, OhioAges 55–82 - NCT06933667Recruiting
Brain health and wellness study for adults 50+
This study looks at brain health and wellness programs for people aged 50 and older. It may help you stay mentally sharp and active.
Toronto, OntarioAges 50 years+ - NCT06781333RecruitingPhase 2
Stem cells for behavior problems in Alzheimer's
This trial tests whether a single infusion of human mesenchymal stem cells (hMSC) can improve difficult behaviors like agitation, anxiety, or hallucinations in people with Alzheimer's disease. It's designed for those who have been taking antipsychotic medication for at least 4 weeks and have a study partner to help track behavior changes.
Miami, FloridaAges 55–90 - NCT06741865Recruiting
Helping older adults keep their minds sharp (INSPIRE-Faith)
This trial tests whether certain lifestyle and thinking exercises help preserve memory and brain function in older adults, especially in the African American community. You may join if you are 55 or older and your memory is normal or mildly impaired.
Los Angeles, CaliforniaAges 55–85 - NCT06928298Recruiting
A cognitive screening study for Spanish speakers aged 60+
This study tests a new, easy-to-use cognitive screening tool on an iPad for older adults who speak Spanish. It aims to help primary care doctors detect thinking or memory changes early.
Austin, TexasAges 60 years+ - NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT06891716RecruitingEarly Phase 1
PET scan for TDP-43 proteinopathies
This study tests a new PET scan dye that may help see TDP-43 protein buildup in the brain, which is linked to certain dementias and ALS. It aims to improve diagnosis and tracking of these conditions.
AmsterdamAges 40–70 - NCT06891703RecruitingEarly Phase 1
PET imaging study for Parkinson's and related conditions
This trial uses a new imaging agent (like a dye) to see signs of Parkinson's disease in the brain. If you have Parkinson's or a related condition like Lewy body dementia or multiple system atrophy, this scan may help researchers better understand these illnesses.
SolnaAges 20 years+ - NCT06898476Recruiting
Silkworm pupa powder for Alzheimer's disease
This study tests if a powder made from silkworm pupae can help improve memory and thinking in people with Alzheimer's disease. It is for people with mild to severe Alzheimer's who have clear signs of the disease in their blood or brain scans.
Hangzhou, ZhejiangAges 50–90 - NCT06883708Recruiting
Online program for dementia caregivers in Malaysia
This trial tests an online program called iSupport-Malaysia to help people who care for a family member with dementia. It aims to reduce stress, burden, and symptoms of depression or anxiety.
Petaling Jaya, Kuala LumpurAges 18–100 - NCT06885918Recruiting
ALS Research Collaborative study
This study is a research collaborative that collects information from people with ALS or their families. It aims to better understand the disease and find markers that could help develop treatments.
Watertown, MassachusettsAges 18 years+ - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT06880406Recruiting
Study of cell energy in Alzheimer's and other dementias
This study looks at how energy production in cells (mitochondria) differs in people with Alzheimer's or other dementias compared to healthy volunteers. It involves a one-time spinal tap to collect fluid for analysis.
Nice, PACAAges 18 years+ - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT06871839Recruiting
A study of lencanumab for early Alzheimer's disease
This trial tests an investigational drug called lencanumab for people with early Alzheimer's disease. The goal is to see if it can help with memory and thinking by targeting brain changes caused by Alzheimer's.
BeijingAges 50–90 - NCT06875986Recruiting
Study of REXULTI for agitation in Alzheimer's disease
This trial is studying how a medication called REXULTI works in patients with Alzheimer's disease who have symptoms like excessive activity, aggression, or mood swings. It aims to see if the drug helps manage these behaviors.
Osaka, OsakaAges 15 years+ - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Phoenix, ArizonaAges 50 years+ - NCT06850597RecruitingPhase 2
Testing dimethyl fumarate for early Alzheimer's disease
This study tests a drug called dimethyl fumarate to see if it can help people with early Alzheimer's disease. It may slow down memory loss and thinking problems.
Lodz, Łódź VoivodeshipAges 55–90 - NCT06855368Recruiting
Biomarkers for tracking dementia progression
This study looks at biological markers to monitor how dementia changes over time. It may help understand the disease better in people with early Alzheimer's or mild cognitive impairment.
RomaAges 18 years+ - NCT06852326Recruiting
Helping caregivers of people with dementia
This study aims to design a support program for informal caregivers of people with Alzheimer's or similar dementias. It works with doctors, nurses, and other experts to understand what help caregivers need.
AmboiseAges 18 years+ - NCT06832761Recruiting
Lifestyle help for people with early memory concerns
This trial tests whether a lifestyle program can help people with mild memory problems (subjective cognitive decline or mild cognitive impairment) who also have at least two things that increase their risk for dementia, like high blood pressure or lack of exercise. If you're 50 or older and have these memory issues and risk factors, you may be able to join.
AmsterdamAges 50 years+ - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06824142Recruiting
Testing a 3D clock for Alzheimer's time orientation
This study tests a 3D tool (like a special clock) to help people with Alzheimer's keep track of time. You may be eligible if you have mild to moderate Alzheimer's and trouble with time orientation.
ChampcueilAges 65 years+
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Common questions
- Are there clinical trials for dementia?
- Yes. Clin2 currently lists 486 recruiting dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.