Clinical trials
Dental Caries clinical trials
Below are recruiting dental caries clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07134114Recruiting
How Hall Crowns Affect Your Child's Bite
This study tests the Hall Technique, a way to place stainless steel crowns on baby molars without numbing or drilling. It looks at how the crown affects your child's bite, and may help kids with cavities in back baby teeth who can cooperate for treatment.
Ankara, KeçiörenAges 7–10 - NCT07213661Recruiting
Long-term results of two cavity treatments
This study looks at how well two cavity treatments work over time. It's for people who already took part in an earlier study at one of 33 housing sites.
Cleveland, OhioAges 62 years+ - NCT07711132Recruiting
Remineralizing toothpaste for early cavities in teens
This trial tests three different treatments for repairing very early cavities on tooth enamel: a nano-eggshell paste, a special milk protein paste (CPP-ACP), and a standard fluoride paste. It is for teenagers and young adults who have a few small spots of early decay and a moderate to high risk of getting cavities.
Al MansurahAges 15–20 - NCT07212660Recruiting
Comparing two curing methods for fillings in baby teeth
This trial tests two different ways of hardening (curing) the material used for fillings in baby molars. It aims to see which method works better and is safer for children needing fillings for cavities or other damage.
Herzogenbuchsee, Canton of BernAges 4–9 - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT06152081Recruiting
Detecting cavities with two new devices
This study tests two different devices for finding cavities in adults at high risk for tooth decay, comparing how well they work against each other and standard methods.
Boston, MassachusettsAges 21 years+ - NCT07250022Recruiting
Checking for hidden decay after tooth fillings in children
This study tests a gentle way to fill cavities in baby teeth (called Atraumatic Restorative Treatment, or ART) to see if some decay is left behind. It may be a good option for children with cavities who are nervous about traditional dental drills.
Çanakkale, KepezAges 4–9 - NCT06898918Enrolling by invitation
Mothers' feeding habits and kids' eating and tooth health
This study looks at how mothers control their child's eating, how the child eats, and whether it relates to early childhood cavities. It may help families understand what affects their preschooler's dental health.
CairoAges 3–5 - NCT06286501Recruiting
Preventive treatment for teens at risk of oral diseases
This trial tests a new preventive treatment for teenagers at risk of tooth decay and gum disease. It uses a special mouthpiece device (Lumoral) to clean teeth better and see if it can prevent oral health problems.
Tampere, PirkanmaaAges 14–16 - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT06863103Enrolling by invitation
Treating children with major dental needs
This study explores how dentists and dental specialists treat children who need a lot of dental work. It aims to improve care for kids with extensive dental needs.
MalmöAges Up to 65 years - NCT07133919Recruiting
AI communication to reduce dental anxiety in children
This trial tests whether a child-friendly, AI-assisted conversation method can help reduce anxiety in children who need a dental filling, pulpotomy, or similar treatment. It is for children ages 6-12 who are coming to the dentist for the first time and will receive local anesthesia.
Çanakkale, KepezAges 7–12 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT07136155Enrolling by invitation
Two ways to treat deep cavities in baby teeth
This study compares two ways to treat deep cavities in baby (primary) molars. One method places a special soothing medicine under a filling; the other uses a metal crown that covers the whole tooth. Both aim to keep the tooth healthy without needing a nerve treatment or extraction.
IrbidAges 4–9 - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT04119180RecruitingPhase 4
Sedation vs protective positioning for kids' dental work
This study compares two ways of keeping children comfortable and safe during dental treatment: sedation or a protective positioning approach. It may help find which method works better for comfort and safety for children who need fillings or other cavity repair.
Goiânia, GoiásAges 1–7 - NCT03969628Recruiting
Testing two ways to check tooth-caries risk in children
This study compares two different methods of estimating how likely a child is to get tooth decay. If you visit the children’s dental clinic, the researchers will use these methods to help identify risk and plan prevention.
Pelotas, Rio Grande do SulAges 7–11 - NCT05979805Recruiting
Education programs to prevent cavities and gum problems during braces
This study compares two types of education programs to see which better prevents cavities and gum inflammation in people getting braces. Participants must be new to orthodontic treatment and have healthy teeth and gums at the start.
BogotáAges 13–28 - NCT06826456Recruiting
Laser treatment to prevent cavities in children's molars
This study tests whether a special laser (Er,Cr:YSGG) can prevent cavities in the deep grooves of children's permanent back teeth. It is for children ages 6–12 who are calm during dental visits and have healthy, groove-filled molars without visible cavities.
AlexandriaAges 6–12 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT04630587Enrolling by invitation
3D-printed fillings for back teeth needing repairs
This study tests how long different types of dental fillings made with 3D printing last in back teeth (premolars and molars). It may help you by comparing filling types in a careful, structured way.
OuluAges 18 years+ - NCT07186673Recruiting
Comparing two types of crowns for back teeth in children
This study compares two ways to fix cavities in children's permanent back molars: a special 'Hall' crown that is placed without numbing or drilling, versus a traditional crown. It aims to see which one works better and is more comfortable for kids.
LatakiaAges 8–15 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT06543680Recruiting
Comparing two tooth-filling materials for non-cavity neck lesions
This trial compares two types of tooth fillings for wear-and-tear cavities that form near the gum line on the side of the tooth (non-carious cervical lesions). It tests whether a newer self-sticking resin composite works as well as a glass ionomer filling that is often used for these spots.
Al Mansurah, DakahliyaAges 30–60
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Common questions
- Are there clinical trials for dental caries?
- Yes. Clin2 currently lists 91 recruiting dental caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.