Clinical trials
Dental Caries clinical trials
Below are recruiting dental caries clinical trials, each written for real people, not researchers. We’re tracking 83 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06753669Recruiting
Mothers' action project for child health
This study looks at how to help mothers from South Asian communities support their child's health and development. You and your child would join a program that provides guidance and resources over 12 months.
New York, New YorkAges 1–45 - NCT07068204Recruiting
Comparing two toothpastes to prevent cavities in healthy adults
This study tests whether a new 2% calcium hypophosphite toothpaste is better than standard fluoride toothpaste at preventing cavities. You may be able to join if you have healthy teeth and are willing to use an electric toothbrush and floss.
Bialystok, PolandAges 18–45 - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT03753256Recruiting
Testing a dental eye scan during orthodontic treatment
This study checks whether an optical coherence tomography scan—a quick, non-invasive imaging test—can help in dentistry for people who need orthodontic (braces/alignment) treatment. If you join, you’ll likely be scanned as part of the study and your dentist/doctor will compare results to see how useful the scan is.
HeidelbergAges 6 years+ - NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40 - NCT06641011Recruiting
Sealing molars with enamel spots: rinsing vs blotting
This study tests whether rinsing off or blotting dry a special silver fluoride liquid before placing a tooth sealant helps the sealant last longer on molars affected by a common condition called molar-incisor hypomineralization. The goal is to find the best way to protect these teeth from cavities.
AnkaraAges 6–14 - NCT07703176Recruiting
Testing a new tooth filling in children's first molars
This study compares how well a newer filling material (Cention-N) works in children's permanent back teeth that have cavities. It's for healthy children ages 8 to 10 who have cavities in both lower or both upper first molars.
Minya, Asyut GovernorateAges 8–10 - NCT07547904Recruiting
Bioactive filling material for back tooth cavities
This trial tests a newer type of tooth-filling material (bioactive bulk-fill) in back teeth that need repair. Researchers will compare how well it works compared to standard fillings, which may help improve how long fillings last.
IstanbulAges 18–50 - NCT07343050Recruiting
Testing flowable composites for tooth fillings and sensitivity
This trial is testing if a special type of dental filling material (flowable composite) causes less tooth sensitivity after getting a cavity filled. It may help people with cavities in the back teeth.
Merkez, Rize ProvinceAges 18 years+ - NCT06699199RecruitingPhase 4
Testing silver diamine fluoride on mouth bacteria in kids
This study tests if a liquid medicine (silver diamine fluoride) painted on baby teeth cavities can change the bacteria in a child's mouth. It is for healthy children ages 4–10 with an open cavity.
Jeddah, Mecca RegionAges 4–12 - NCT07324928Enrolling by invitation
Pulpotomy treatment for baby teeth using iron sulfate or MTA
This study compares two materials (iron sulfate and a special cement called MTA) used during a pulpotomy—a procedure to treat cavities in baby molars when the nerve is exposed. It aims to find which material works better to keep the tooth healthy until it falls out naturally.
Jizan, Jazan RegionAges 6–10 - NCT07302581Recruiting
Study of dental implants with natural ligament for single tooth replacement
This trial tests a new type of dental implant that includes a ligament (like a natural tooth's shock absorber). It's for people who need to have a single front or side tooth pulled and have healthy gum and bone around the area. The goal is to see if this implant works well and stays healthy over time.
Kōriyama, FukushimaAges 18 years+ - NCT07244991Recruiting
Effect of a special toothpaste on plaque bacteria and cavities during braces treatment
This trial tests whether a special paste (MI Paste Plus) can reduce cavity-causing bacteria and prevent early white spots on teeth while you are wearing braces.
Tirana, AlbaniaAges 5–45 - NCT07181967Recruiting
SDF vs fluoride varnish for cavity bacteria in kids
This study compares a silver-containing liquid (SDF) to a fluoride varnish to see which works better at reducing cavity-causing bacteria in children's mouths. It may help your child if they have cavities in their baby teeth.
Asyut, Asyut GovernorateAges 3–8 - NCT07146464Recruiting
Peptide vs calcium paste for early cavity spots
This trial tests whether a new peptide treatment or a calcium-phosphate paste works better at reversing early white-spot cavities on front teeth. If you're a young adult with early decay on your front teeth, you may be able to join.
Cairo, Cairo GovernorateAges 15–25 - NCT04040920Recruiting
Ozone treatment before dental sealants
This trial tests whether applying ozone to certain back teeth before placing sealants helps the sealants work better. You might qualify if you need sealants on specific molars and can safely have the area isolated during treatment.
Trieste, TriesteAges 6–16 - NCT07009015Recruiting
Oral health program for children
This study tests whether an oral health program helps improve children's knowledge and habits. It is for boys aged 10 to 11 who have their parent's permission.
Serdang, SelangorAges 10–11 - NCT07011381Enrolling by invitation
Parent views on children's oral health: refugees vs Egyptians
This study looks at how parents view their child's oral health (teeth and mouth) and how it affects daily life. It compares views of Sudanese refugee parents and Egyptian parents living in Cairo.
Kafr ash Shaykh, Kafr Ash Shaikh/ ElhamrawyAges 6–12 - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT06714929Recruiting
School water study for students in grades K-5
This study looks at how a new water program in schools might affect student health and hydration. It includes watching what kids drink at lunch, checking teeth and body weight for older students, and asking 4th and 5th graders and staff about their drinks.
Henrico, VirginiaAges 4 years+ - NCT06685640Recruiting
Comparing metal and ceramic crowns for back baby teeth
This trial tests whether stainless steel or zirconia crowns work better for fixing cavities in children's back baby teeth after nerve treatment. It can help parents choose the best option for their child.
Aydin, AydınAges 4–5 - NCT06555029Recruiting
Oral health help for older adults on Medicaid
This trial is testing an oral health program offered during routine primary care visits for older adults (55+) on Medicaid. It aims to see if adding dental care support to regular check-ups can improve health.
Cleveland, OhioAges 55 years+
Hear when a new Dental Caries trial opens
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Common questions
- Are there clinical trials for dental caries?
- Yes. Clin2 currently lists 83 recruiting dental caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.