Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 490 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07330518Recruiting
Comparing two numbing techniques for lower tooth removal
This study compares two ways to numb the lower jaw for removing a back tooth: one blocks a small nerve near the cheek, the other blocks the main nerve trunk. The goal is to see which method works better and causes less discomfort.
Islamabad, Islamabad, PakistanAges 20–60 - NCT07337057Recruiting
Standardized dental implant outcomes
This study is creating a standard way to measure the success of dental implants. It is for people who need a new implant or a replacement implant, and who do not have major health or mouth problems that would complicate the procedure.
Rotterdam, South HollandAges 18–75 - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT06149585Recruiting
Bacteria changes in gum disease patients getting all dental implants
This study looks at how bacteria in your mouth change when all your teeth are removed and replaced with dental implants. If you have severe gum disease and need all your teeth extracted, joining this trial could help researchers understand your healing process.
Cleveland, OhioAges 21 years+ - NCT07349056Recruiting
Early effects of jaw surgery on gum health
This trial looks at how jaw surgery affects your gums and supporting tissues over six months. It may help if you have certain jaw misalignments need surgery.
EdirneAges 18–65 - NCT07355400Recruiting
NeoPill device for reducing mouth bacteria in braces patients
This trial tests a device called NeoPill to reduce bacteria in the mouths of people with braces. It involves a single visit and may help control oral bacteria levels.
LimassolAges 18 years+ - NCT07364565Recruiting
Green tea mouthwash for plaque and gum health
This trial tests whether a pure green tea mouthwash can reduce plaque and gum inflammation better than a placebo or an essential oils mouthwash. It may be a good option if you have healthy gums and are looking for a natural alternative.
Irbid, Irbid GovernorateAges 18 years+ - NCT01568697Recruiting
Studying gum disease in people with immune and genetic differences
This study looks at how mouth bacteria and the immune system may work together to cause gum disease (periodontitis), especially in people with certain genetic immune problems. It may help researchers understand what drives severe gum disease and how to better monitor or treat it in the future.
Bethesda, MarylandAges 7–100 - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT01425892Recruiting
Study of how Sjogren’s disease starts and changes over time
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Bethesda, MarylandAges 16–100 - NCT00227253Recruiting
Study center for people with Chromosome 18
This trial is for people with Chromosome 18 (or the parent/guardian of a child with it) to take part in medical checkups and study evaluations. It may help researchers learn more about the condition and how to best evaluate patients safely.
San Antonio, TexasAges Any age - NCT00804154RecruitingPhase 1
Capsaicin-like drug for severe cancer pain
This Phase 1 trial tests a new drug related to capsaicin (resiniferatoxin) to reduce severe nerve pain from advanced cancer. It is given through a small catheter near the spinal fluid space and is meant for people whose pain medicines and other options have not worked well enough.
Bethesda, MarylandAges 18–99 - NCT02327884Recruiting
Study saliva and related diseases to learn health patterns
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
Bethesda, MarylandAges 4–100 - NCT02639312Recruiting
Study of how craniofacial differences develop over time
This study follows children and adults with craniofacial (head/face) differences to learn how their growth changes over time. It also enrolls unaffected family members and healthy volunteers to compare what is “typical,” using scans and optional genetic testing.
Bethesda, MarylandAges 2–100 - NCT07671651Recruiting
Ozone therapy for early tooth decay in children
This trial tests whether ozone therapy can help reverse the earliest stages of tooth decay (white spots on teeth) in children. Children aged 6–12 with small, non-cavity spots may benefit from this treatment instead of traditional fillings.
Istanbul, MaltepeAges 6–14 - NCT07405905Recruiting
Comparing mini implant placements for fixing upper teeth overbite
This study tests two ways of placing small temporary anchors (mini implants) in the jaw to help pull upper front teeth back into a better position. It is for patients who have finished growing and have a Class II overbite, to see which anchor location works best.
Rohtak, HaryanaAges 18–30 - NCT07413055RecruitingPhase 3
Comparing two doses of dexamethasone for dental implant pain
This study tests whether a higher dose of dexamethasone (8 mg) works better than a lower dose (4 mg) for reducing pain after getting a single dental implant. It may help find the best way to manage discomfort after surgery.
MuscatAges 21–80 - NCT07414173RecruitingPhase 4
Mouthrinse for plaque and gum health
This study tests whether a special antimicrobial mouthrinse can reduce plaque buildup and improve gum health over 6 months. If you have early gum disease (gingivitis) and are generally healthy, this trial may be a good fit.
SchenefeldAges 18–70 - NCT07415733Recruiting
Gum health toothpaste study for people with bleeding gums
This trial tests a toothpaste designed to improve gum health in people who have gingival problems like bleeding gums. It aims to see if the toothpaste can reduce gum bleeding and improve overall gum condition.
Jakarta PusatAges 18 years+ - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT07464197Recruiting
Tooth whitening with custom 3D-printed trays
This study tests if 3D-printed whitening trays work as well as regular custom trays. You'll use a whitening gel at home for a short time to see how white your teeth get.
Sant Cugat del Vallès, BARCELONAAges 18 years+ - NCT07471386Recruiting
Gum graft for implant infection
This trial tests whether adding gum tissue around a dental implant helps treat an infection around the implant. It may be a good fit if you have a dental implant with inflammation and very little attached gum.
AnkaraAges 18–75 - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5
Hear when a new Dental trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 490 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.