Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT05943782Enrolling by invitation
Digital onlay fillings made two ways for back teeth
This trial compares two digital manufacturing methods to make ceramic onlay fillings for back (molar) teeth—one method that removes material and one that builds it up. It may help you learn which approach makes more comfortable, effective onlays for teeth needing repair.
CairoAges 18–50 - NCT05888935Recruiting
AI checks for tooth root infections on dental X-rays
This study tests an artificial intelligence tool to detect small infections around tooth roots using routine panoramic dental X-rays. You might benefit if your scans are used to more accurately spot these problems compared with standard reading.
MetzAges 18 years+ - NCT05851963Recruiting
Toothbrushing help for teens with fixed braces
This study looks at whether using specific toothbrushes in daily life can improve dental gum and tooth health for teens with fixed braces. It may help by testing simple at-home brushing routines that could reduce gum problems during orthodontic treatment.
NancyAges 11–15 - NCT05772962Recruiting
Dental record study for children at risk
This study collects children’s dental records to learn about oral health in children who are considered at risk. Your participation could help researchers understand what dental problems happen more often and why.
Bergen, VestlandAges birth–18 years - NCT05721781Recruiting
Reducing infection risk after gum and tooth issues
This study looks at ways to lower the risk of infective endocarditis, a serious heart infection that can happen after certain bacteria enter the bloodstream from the mouth. You may be asked to pause routine dental cleanings for a period while they track dental health and infection risk.
Boston, MassachusettsAges 18 years+ - NCT05688982Recruiting
Check oral health needs and local care resources in the ER
This study asks people in the emergency department (and their parents/guardians) about oral health needs and what local resources they can access. It aims to map gaps in dental and oral health support so future care can be better targeted.
Boston, MassachusettsAges 1 year+ - NCT05470023Recruiting
Imaging study of gum health and mouth biofilm
This study uses imaging to look at how healthy your gums are and how much “plaque/biofilm” is in your mouth. It may help researchers better understand gum health and how oral hygiene affects it.
Irvine, CaliforniaAges 18 years+ - NCT05444127Recruiting
Study of oral health in people with Wilson’s disease
This study compares oral (mouth and teeth) health in people with Wilson’s disease versus people without it. It aims to see whether Wilson’s disease is linked to specific dental and imaging findings, which could help with future prevention and care.
Ivry-sur-SeineAges 18 years+ - NCT05439330Recruiting
Dental MRI to help diagnose jaw, gum, and tooth problems
This study tests whether a special dental MRI can give useful pictures to diagnose jaw joint problems, tooth-related tissue changes, and gum/inflammation issues, and to help plan some dental implant treatments. If you need imaging for these reasons, the trial may help doctors choose the best next treatment by using clearer, dedicated scans.
AarhusAges 18 years+ - NCT04954664Recruiting
Bone graft particles to help dental implants fit in missing teeth areas
This study tests a bone-grafting approach (using processed donor bone particles, with or without a growth factor) to help dental implants work when the jaw bone is too narrow. It may help people get implants placed more safely and effectively in areas with missing teeth.
Birmingham, AlabamaAges 18–99 - NCT05122897Recruiting
Study of plaque biofilm on temporary implant crown rings
This study looks at how plaque-biofilm (a thin layer of germs that can stick to surfaces) forms on temporary parts of dental implant crowns. If you have dental implants and are healthy and stable with gum health, your care team may use specific temporary rings to study biofilm buildup.
BaselAges 18 years+ - NCT00227253Recruiting
Study center for people with Chromosome 18
This trial is for people with Chromosome 18 (or the parent/guardian of a child with it) to take part in medical checkups and study evaluations. It may help researchers learn more about the condition and how to best evaluate patients safely.
San Antonio, TexasAges Any age - NCT04920136Recruiting
Tissue graft to strengthen gum around teeth or implants
This study tests a gum-repair approach that may help create more durable, firm gum tissue around teeth or dental implants. If your area lacks “keratinized” (firmer, protective) gum tissue, this could improve comfort and stability after dental work.
Birmingham, AlabamaAges 18–99 - NCT04880707RecruitingPhase 2
Pain medication options for lower wisdom tooth removal
This study compares pain-medication approaches during and after removing at least one lower impacted wisdom tooth (a tooth that’s stuck). It may help find a safer or more effective way to control dental pain after surgery.
Newark, New JerseyAges 18 years+ - NCT04805320Recruiting
Study of gum inflammation after tooth removal
This study looks at how gum (periodontal) inflammation affects the body’s immune response during wound healing after a tooth is taken out. You might be considered because you need a molar or premolar extraction where the tooth cannot be repaired.
Lincoln, NebraskaAges 21–70 - NCT04693949Recruiting
A study on a new coating for dental bridges
This trial tests a special coating for dental bridges made from a strong white material (zirconia). It may help the bridge bond better to your tooth.
LjubljanaAges Any age - NCT04605445Recruiting
One vs two dentist visits for infected root canals
This study compares whether treating an infected, dead tooth in one visit works as well as using two visits. It may help you and your dentist choose the simplest schedule while still clearing infection and supporting healing.
Vaxjo, Kronoberg CountyAges 18 years+ - NCT04544839Enrolling by invitation
Test two ways to attach dentures or implants
This trial compares two different attachment systems for people who have major problems with their upper and/or lower dentures, or who want implant-supported replacement teeth. It may help your smile and chewing by improving how the replacement teeth stay firmly in place.
PuneAges 18 years+ - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT03384537RecruitingEarly Phase 1
Tropolone mouthwash test in healthy adults
This early trial compares a mouthwash that contains tropolone versus a mouthwash without tropolone to see how well each works against germs in the mouth. You may be asked to pause your usual mouth-cleaning routine for a few days beforehand.
CairoAges 18–45 - NCT02327884Recruiting
Study saliva and related diseases to learn health patterns
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
Bethesda, MarylandAges 4–100 - NCT02639312Recruiting
Study of how craniofacial differences develop over time
This study follows children and adults with craniofacial (head/face) differences to learn how their growth changes over time. It also enrolls unaffected family members and healthy volunteers to compare what is “typical,” using scans and optional genetic testing.
Bethesda, MarylandAges 2–100 - NCT01425892Recruiting
Study of how Sjogren’s disease starts and changes over time
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Bethesda, MarylandAges 16–100
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 459 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.