Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03320304Recruiting
VNS for long-term depression that hasn’t improved with treatment
This trial studies how well and how efficiently VNS therapy works for people with long-lasting or repeated major depression that hasn’t responded to enough antidepressant treatments. It may help patients who are already receiving depression treatment but are still struggling.
ViennaAges 18 years+ - NCT03388606Recruiting
Studying adolescent depression and how to treat it
This study looks closely at how depression shows up in teens and tests approaches to treatment. It may help teens and families better understand depression and get access to structured care as part of research.
Los Angeles, CaliforniaAges 11–25 - NCT03417960Recruiting
Accelerated brain stimulation for postpartum depression
This trial studies an intensive form of noninvasive brain stimulation (treatments given through the scalp) for postpartum depression. It aims to reduce depression symptoms and improve wellbeing in people who are at least 18 and have moderate symptoms.
Charleston, South CarolinaAges 18–50 - NCT02994433RecruitingPhase 1
Testing nitrous oxide for depression brain circuit activity
This early study tests whether nitrous oxide, aimed at specific brain circuits, can change depression-related brain activity. It is mainly for adults with major depression or treatment-resistant depression, and includes brain imaging during the study.
St Louis, MissouriAges 18–65 - NCT02122562RecruitingPhase 2
Ketamine treatment for depression that hasn’t responded to care
This Phase 2 study tests ketamine for people with major depression that hasn’t improved after at least one antidepressant. It aims to see whether ketamine can reduce depression symptoms during a current depressive episode.
Iowa City, IowaAges 18–55 - NCT07878286Recruiting
How body awareness relates to fibromyalgia symptoms
This study looks at how well women with fibromyalgia notice internal body signals (like heartbeat or breathing) and whether that affects their pain and other symptoms. It may help doctors understand fibromyalgia better and improve future treatments.
IstanbulAges 18–65 - NCT06627764Recruiting
Family support program for Latino families with teens
This study tests a family-based program to help Latino families with teenagers aged 12-17. The program addresses overlapping health and social challenges to improve family well-being.
Durham, North CarolinaAges 12–100 - NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT03065413Recruiting
Study of heart health, habits, and mood in sailors
This study looks at how common heart and blood vessel problems are, and how changes in activity, diet, and anxiety or depression show up over time in naval personnel. It may help improve understanding of risk factors and mental well-being in this group.
Athens, AthensAges 18 years+ - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT04911829Recruiting
Program for persistent low-grade depression and treatment changes
This trial looks at how treatment for persistent depressive disorder (long-lasting low mood) affects real-world costs and the process of changing treatments. It may help people who have tried some treatments before and need a practical plan moving forward.
Vikersund, BuskerudAges 18–70 - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT01415310Recruiting
Registering geriatric mental health patients and families
This study sets up a quality registry to better understand and improve care in geriatric psychiatry units. It includes patients who receive care there and their relatives, as long as they agree to take part by signing consent.
OsloAges 65 years+ - NCT05480150Recruiting
Study of brain and mood in people with depression or bipolar disorder
This study is following and assessing people with major depression or bipolar disorder to better understand the condition and how the brain relates to symptoms. It may help researchers develop more targeted support by comparing brain and health information over time.
Hangzhou, ZhejiangAges 16–65 - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05366270Recruiting
Testing how mild heat affects depression symptoms and brain signals
This study tests whether controlled whole-body heat can change immune-related brain and body signals in people with major depressive disorder. It may help researchers understand why heat affects mood and who might benefit, while closely monitoring safety.
Boston, MassachusettsAges 18–65 - NCT05800522Recruiting
Supportive parenting program for kids with behavior and mood struggles
This trial tests whether a supportive parenting program can help children who are showing higher-than-usual symptoms like anxiety, depression, anger, or behavior problems. If you’re not already in certain specialized mental health programs, your child may be able to join and get structured support for coping.
OsloAges 4–12 - NCT05648539Recruiting
Music therapy for mood and anxiety symptoms
This trial studies whether music therapy can improve symptoms of depression or anxiety. You may be invited if you have mild mood or anxiety symptoms on common screening questionnaires.
Nanjing, JiangsuAges 16–35 - NCT04499066Recruiting
Mental health study during early pregnancy in Guangzhou
This study follows pregnant people in early pregnancy to better understand mental health during the perinatal (pregnancy and around delivery) period. It may help the clinic improve support for mental well-being before and after birth.
Guangzhou, GuangdongAges Any age - NCT05388461Recruiting
Follow-up after ECT for major depression
This study checks how well electroconvulsive therapy (ECT) works for people with major depression right after treatment and again 6 months later. You may be able to take part if you had ECT for major depression at the specified hospitals and agree to be included in a neurostimulation follow-up registry.
BergenAges 18 years+ - NCT06104696Recruiting
Comprehensive Geriatric Assessment in Kidney Transplant Patients Over 60
This study looks at how a full health review (geriatric assessment) can help older adults who are getting or have gotten a new kidney. It aims to improve care and outcomes for patients aged 60 and over.
PragueAges 60 years+ - NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT06654414Recruiting
Smoking cessation support for transgender and gender-diverse adults
This study tests a skills-based program to help transgender and gender-diverse adults quit smoking or vaping. The program focuses on managing stress related to identity and health, and may be more supportive than standard quit programs.
Boston, MassachusettsAges 18 years+ - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.