Clinical trials
Depression and Suicide clinical trials
Below are recruiting depression and suicide clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05426057Recruiting
Mental health support for Hispanic teens with caregiver involvement
This study looks at improving mental health in primary care by involving both a teen and an adult caregiver. It may help families who are struggling with communication, depression or anxiety symptoms, or past suicidal thoughts or behaviors.
Miami, FloridaAges 12–16 - NCT05485701Recruiting
Study of perinatal mental health in India
This study looks at mental health during pregnancy and after birth, and may help improve how these concerns are understood and assessed. You may be interviewed or asked to complete surveys across a few visits, depending on which part of the study you join.
Kangra, Himachal PradeshAges 18–45 - NCT07611916Enrolling by invitation
App-based support for group therapy in the hospital
This study tests if adding a smartphone app to group therapy helps people in the hospital feel better. It is for adults who can speak English and have a smartphone.
Piscataway, New JerseyAges 18 years+ - NCT06829953Recruiting
App-based study for teens with depression
This study is testing whether a smartphone app can help teens who feel depressed and have lost interest in things. It's looking for youth aged 12–18 with moderate to severe depression who are willing to use the app.
Philadelphia, PennsylvaniaAges 12–18 - NCT07217444Recruiting
Deep TMS for depression in teens
This trial tests whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) can help teens with moderate to severe depression feel better. It involves wearing a special magnetic coil on the head during several sessions.
Cincinnati, OhioAges 14–18 - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06854224RecruitingPhase 2
Testing a sleep drug for suicide risk in veterans with depression
This trial tests whether a medication called suvorexant (used for sleep) can help lower suicide risk in veterans who have major depression and have attempted suicide before. The study aims to see if blocking a brain chemical called orexin reduces suicidal thoughts.
The Bronx, New YorkAges 18–70 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT07278752Enrolling by invitation
Social media and emotions in teens study
This study looks at how social media affects teenagers' emotions and daily experiences. Participants will use a smartphone app to track their feelings and social media use over time.
Dallas, TexasAges 13–18 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT05652153Recruiting
Brain-signal study for teens with depression and suicide thoughts
This study looks at how certain brain “inhibitory” signals work in teenagers and young adults who have depression and either suicide thoughts or past suicide behavior. The goal is to better understand suicide risk and what might help reduce it, using brain and brainwave testing.
Minneapolis, MinnesotaAges 13–21 - NCT07078227Recruiting
Long-term depression follow-up study
This study follows up with people who took part in an earlier research project on depression and genetics. The goal is to see how depression changes over time.
LundAges 18 years+ - NCT07305701Recruiting
Study on Medical Students' Mental Health
This study follows first-year health students at the University of Orléans to understand their mental health over time. It aims to find ways to support students' well-being during their studies.
Orléans, LoiretAges 18 years+ - NCT05450432RecruitingPhase 4
Ketamine maintenance to help prevent suicidal thoughts
This Phase 4 study tests whether ongoing treatment with ketamine or esketamine can reduce suicidal thoughts in people with major depression who are at high risk. Because the study focuses on long-term maintenance, you’d receive treatment over time while being closely monitored for safety and mental health changes.
Boston, MassachusettsAges 18–70 - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT07569198RecruitingPhase 2
Ketamine plus therapy for depression with suicidal thoughts
This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.
Toronto, OntarioAges 18–70 - NCT05852314Recruiting
Problem-solving support for new mothers with suicidal thoughts
This trial tests a structured problem-solving counseling approach for women who are feeling suicidal during the post-birth period. It may help by reducing suicidal thoughts for mothers who do not need urgent hospital-level psychiatric care.
Rawalpindi, Punjab ProvinceAges 16–44 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT02443636Recruiting
Join a depression and mental health research registry in Atlantic Canada
This trial is a “registry,” meaning you can share your health information to help researchers study depression and other mental health needs in Atlantic Canada. Being part of the registry may help researchers understand patterns and improve future support and treatments.
Halifax, Nova ScotiaAges Any age - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60
Hear when a new Depression and Suicide trial opens
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Common questions
- Are there clinical trials for depression and suicide?
- Yes. Clin2 currently lists 69 recruiting depression and suicide studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and suicide trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and suicide trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.