Clinical trials
Depression Anxiety Disorder clinical trials
Below are recruiting depression anxiety disorder clinical trials, each written for real people, not researchers. We’re tracking 454 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04663724Recruiting
Computer-based therapy for social anxiety
This trial tests a computer-based treatment to help people with social anxiety (fear or avoidance of social situations). If you qualify, you may receive structured online therapy designed to reduce social anxiety symptoms.
New York, New YorkAges 18–60 - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT05772104RecruitingPhase 3
Test a Chinese herbal capsule for generalized anxiety
This Phase 3 trial studies Shugan Jieyu Capsule to treat generalized anxiety disorder (GAD). It aims to see if it can reduce anxiety symptoms in people who fit specific anxiety severity and traditional diagnosis criteria.
BeijingAges 18–65 - NCT06384196Recruiting
Virtual-reality therapy for anxiety and depression in young people
This study tests a new virtual-reality therapy for young people struggling with anxiety or depression. It aims to help you feel better by addressing both conditions together.
BadalonaAges 16–29 - NCT06429956Recruiting
Combined online therapy for anxiety and depression
This trial tests a new type of therapy that combines different treatment methods for anxiety and depression. It is completely online, so you can join from home, and it aims to help you feel better by tailoring the therapy to your needs.
AarhusAges 18 years+ - NCT06556589Recruiting
Collaborative care for depression and anxiety
This trial tests a collaborative care model to help treat depression and anxiety. If you are a Kaiser Permanente member with recent depression or anxiety and are overdue for a screening, you may be eligible to join and receive extra support.
Aurora, ColoradoAges 18 years+ - NCT06843044RecruitingPhase 4
Testing Ranquilon for anxiety from stress or exhaustion
This study tests a new medication called Ranquilon to see how well it treats anxiety in people with neurasthenia or adjustment disorders. Participants will take the study drug for about 4 weeks, and doctors will check their anxiety and fatigue levels.
Engel'sAges 18–70 - NCT06846320RecruitingPhase 2
Study of ABBV-932 for generalized anxiety disorder
This trial tests an oral medicine called ABBV-932 when added to current antidepressant therapy for people with generalized anxiety disorder (GAD) who still have symptoms. It aims to see if the combination can improve anxiety and reduce side effects.
Huntsville, AlabamaAges 18–65 - NCT06860958RecruitingPhase 3
Adding roflumilast to antidepressants for depression
This study tests if adding roflumilast, a medicine that reduces inflammation, can help people with major depression feel better when taken with their current antidepressant. It is for adults with moderate to severe depression.
TantaAges 18–65 - NCT07115329RecruitingPhase 2
Testing Zelquistinel for major depression
This study tests a new oral medication called Zelquistinel (taken as a tablet) against a placebo for treating major depressive disorder. Researchers want to see if it can reduce depression symptoms, especially when other antidepressants haven't been tried or haven't worked.
Phoenix, ArizonaAges 18–64 - NCT07121712Recruiting
Brain Stimulation for Generalized Anxiety Disorder
This study tests a non-invasive brain stimulation technique (cTBS) to treat Generalized Anxiety Disorder. You will receive navigated stimulation sessions, and no surgery or medication is used.
Hefei, AnhuiAges 18–60 - NCT07201844Recruiting
Does patient choice improve online anxiety treatment?
This trial tests whether letting patients choose their own treatment approach within an online therapy program helps them more for generalized anxiety disorder. You'd receive 10 weeks of internet-delivered cognitive behavior therapy (iCBT) from home.
Stockholm, SverigeAges 18 years+ - NCT07204314RecruitingPhase 3
Study of vortioxetine for teens with depression in Japan
This trial tests whether vortioxetine helps reduce symptoms of major depression in Japanese teenagers aged 12-17. It compares the study drug to a placebo to see if it is safe and effective.
Nagoya, Aichi-kenAges 12–17 - NCT07226661RecruitingPhase 2
Study of an investigational drug for depression
This trial tests an investigational medication for adults with major depressive disorder who are currently taking an antidepressant but still have symptoms. It aims to see if adding this new drug can improve mood better than a placebo.
Garden Grove, CaliforniaAges 18–70 - NCT07323784RecruitingPhase 2
Study of NTX-1472 for social anxiety disorder
This trial tests an investigational medicine called NTX-1472 to see if it helps people with social anxiety disorder. Participation involves taking the study drug and attending scheduled visits.
Pheonix, ArizonaAges 18–65 - NCT07330648RecruitingPhase 2
Crisugabalin for generalized anxiety disorder
This study tests a new investigational drug called crisugabalin for people with generalized anxiety disorder (GAD) who have not found enough relief from at least two other anxiety medications. The trial aims to see if crisugabalin can safely reduce anxiety symptoms.
Hefei, AnhuiAges 18 years+ - NCT07466277Recruiting
Brain stimulation for social anxiety disorder
This study tests if a non-invasive brain stimulation technique called theta burst stimulation can help treat social anxiety disorder. It uses magnetic pulses to target a brain area involved in fear and anxiety, and you may benefit if you have social anxiety and are not taking certain medications.
Hangzhou, ZhejiangAges 16–70 - NCT07477990RecruitingPhase 3
Testing a digital device for anxiety treatment
This trial is testing a digital device called Aurora that helps treat moderate to severe anxiety. It compares the device to standard anxiety medications, so you may receive either the device or a pill. The goal is to see if the device can work as well as medication without the side effects.
Mexico City, Mexico CityAges 18–65 - NCT07478744RecruitingPhase 2
Study for generalized anxiety disorder with SYT-510
This trial tests a new medicine called SYT-510 for adults with generalized anxiety disorder who are not currently taking medication. It aims to see if the drug reduces anxiety and is safe.
LondonAges 18–55 - NCT07523048RecruitingPhase 2
Dextromethorphan-Bupropion for Moderate-to-Severe Depression
This study tests a combination medication (dextromethorphan plus bupropion) to see how it affects brain activity in people with moderate-to-severe depression. Researchers use brain imaging (fMRI) to understand how the drug works and whether it may help relieve depression symptoms.
Toronto, OntarioAges 18–65 - NCT04509102Enrolling by invitationEarly Phase 1
Test added stimulant medicine with rTMS for depression
This early study tests whether adding a stimulant medicine to repetitive TMS (a non-drug brain stimulation) can improve depression. It is aimed at people whose depression has not improved after at least two antidepressant tries.
Los Angeles, CaliforniaAges 18–65 - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for depression anxiety disorder?
- Yes. Clin2 currently lists 454 recruiting depression anxiety disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression anxiety disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression anxiety disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.