Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 441 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07705776Recruiting
SanaMente: A peer-led program for Latino/a well-being
This trial tests a peer-led program called SanaMente to help rural Latino/a adults manage stress, improve mood, and prevent or manage chronic health conditions like diabetes or heart disease. You'll join either group or one-on-one sessions focused on emotional and physical health.
Carbondale, ColoradoAges 18 years+ - NCT07704138Recruiting
Testing process-based therapy for depression and anxiety
This trial tests a type of talking therapy called process-based therapy to see how well it works in everyday care. It focuses on treating depression or anxiety and helps therapists learn how to make better treatment decisions.
Frankfurt am Main, HesseAges 18–65 - NCT07673380RecruitingPhase 2
Mobile health for opioid recovery and mental health
This study uses a mobile health app to help Black and African American individuals recover from opioid or stimulant use and improve mental health. It aims to see if the app can support treatment and well-being.
St Louis, MissouriAges 18 years+ - NCT07669805Recruiting
Mindfulness and lifestyle program for older adults
This study tests a program that combines mindfulness practices and lifestyle changes to improve well-being in adults aged 55 and older. It may help reduce loneliness and support mental health.
Hualien City, TaiwanAges 55 years+ - NCT07637799Recruiting
Parent support group for teens with autism and anxiety or depression
This study tests whether a parent support group helps families manage anxiety or depression in teenagers who have autism. The group teaches parents skills to support their teen at home.
GothenburgAges 12 years+ - NCT06038409Recruiting
Ketamine therapy for chronic conditions
This trial tests if ketamine can help people with long-term health issues. It aims to find new treatments for chronic conditions that haven't responded well to other therapies.
Helena, MontanaAges 18 years+ - NCT07613008Recruiting
Mobile app to prevent perinatal depression and anxiety
This study tests a personalized smartphone app designed to help pregnant women and their partners prevent depression and anxiety during pregnancy and after birth. Participants use the app for support and receive check-ins from healthcare providers.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT07606248Recruiting
Virtual forest mindfulness for pregnant women's mental health
This study tests whether using virtual reality to explore a calming digital forest helps reduce stress and improve mood during pregnancy. You'd use a VR headset a few times to practice mindfulness (focused breathing and relaxation) and complete short surveys about how you're feeling.
HsinchuAges 18 years+ - NCT07609550Recruiting
Early mental health support for pregnant and new mothers
This study tests whether connecting pregnant women and new mothers who have depression or anxiety to mental health care earlier helps them. You'll be part of a larger research program and may receive support through a smartphone app.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT07600411Recruiting
Weight-loss surgery and mood: comparing two surgical approaches
This study follows patients undergoing one of two common weight-loss surgeries (sleeve gastrectomy or gastric bypass) to see how each affects binge eating, depression, and anxiety. Researchers want to understand which surgery may help improve both weight and mental health outcomes.
Cairo, Al-Manial CairoAges 18–60 - NCT07561515Enrolling by invitation
Sound Therapy for Anxiety, Stress, and Depression
This study tests whether listening to specially designed sound can help reduce anxiety, stress, or depression. You'll participate for 3 weeks and answer questionnaires about how you feel.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06773338Recruiting
Can playing Tetris improve mental health for migrants?
This study tests if playing the game Tetris can help reduce stress and improve mood for Arabic-speaking immigrants who have applied for asylum. You would play Tetris a few times and report how you feel.
The Hague, NLAges 18 years+ - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+ - NCT07480668Recruiting
Aromatherapy for emotional wellness during IVF
This study tests whether inhaling lavender essential oil can help reduce anxiety, stress, and depression for women waiting for IVF. You may benefit if you are feeling some emotional distress and are not using other mind-body or herbal treatments.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07467564Recruiting
Does Dupilumab help anxiety and depression in eczema?
This study looks at whether Dupilumab (a treatment for moderate-to-severe eczema) can also help improve symptoms of anxiety and depression. It is for people with eczema who also have these mood symptoms and are about to start Dupilumab.
DohaAges 12 years+ - NCT07464860Recruiting
Breathwork for older adults after knee surgery
This study tests a breathing exercise program to help older adults recover after knee replacement surgery. Participants practice controlled breathing at home using a smartphone or computer.
Tucson, ArizonaAges 65 years+ - NCT07458100Recruiting
Step-by-step digital therapy for emotional disorders
This trial tests a digital stepped-care program for people with emotional disorders like depression, anxiety, OCD, PTSD, or eating disorders. It uses online tools to help manage symptoms, and you may access different levels of support based on your needs.
BeijingAges 18–65 - NCT07436351Recruiting
ACT With CF Self-Help Toolkit
This trial tests an online self-help program based on acceptance and commitment therapy (ACT) for adults with cystic fibrosis who are feeling depressed or anxious. It aims to help you manage these feelings and improve your well-being.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT07391540Recruiting
Internet therapy for financial stress
This trial tests an internet-based cognitive behavioral therapy (ICBT) program for people feeling mild to moderate psychological symptoms because of money worries. It aims to see if online treatment can help reduce these symptoms.
Linköping, Östergötland CountyAges 18 years+ - NCT07375485Enrolling by invitation
Occupational therapy for brain injury recovery at home
This trial explores how occupational therapy can help people with brain injuries stay engaged in daily life. Researchers want to learn from therapists working in home or community settings to improve care.
Denver, ColoradoAges 18 years+ - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 441 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.