Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 441 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06871397Recruiting
Online support program for well-being in early pregnancy
This study tests an online program designed to help pregnant women feel better emotionally and mentally. It includes lessons and support you can access from your phone.
Reus, TarragonaAges 18 years+ - NCT04191811Recruiting
Using brain signals to predict CBT success for mood or sleep issues
This study tests whether brain measurements can help predict who will benefit from a type of talk therapy called CBT (cognitive behavioral therapy). If you have depression, social anxiety, or insomnia, your brain “response variability” may be used to personalize or improve treatment planning.
Huddinge, Stockholm CountyAges 18 years+ - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06906003Recruiting
Vision rehab and depression in age-related macular degeneration
This trial tests whether visual rehabilitation can help improve both vision and mood in people with advanced dry age-related macular degeneration. It aims to understand the link between vision loss and depression.
Rome, ItalyAges 55 years+ - NCT06627764Recruiting
Family support program for Latino families with teens
This study tests a family-based program to help Latino families with teenagers aged 12-17. The program addresses overlapping health and social challenges to improve family well-being.
Durham, North CarolinaAges 12–100 - NCT03065413Recruiting
Study of heart health, habits, and mood in sailors
This study looks at how common heart and blood vessel problems are, and how changes in activity, diet, and anxiety or depression show up over time in naval personnel. It may help improve understanding of risk factors and mental well-being in this group.
Athens, AthensAges 18 years+ - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05648539Recruiting
Music therapy for mood and anxiety symptoms
This trial studies whether music therapy can improve symptoms of depression or anxiety. You may be invited if you have mild mood or anxiety symptoms on common screening questionnaires.
Nanjing, JiangsuAges 16–35 - NCT04499066Recruiting
Mental health study during early pregnancy in Guangzhou
This study follows pregnant people in early pregnancy to better understand mental health during the perinatal (pregnancy and around delivery) period. It may help the clinic improve support for mental well-being before and after birth.
Guangzhou, GuangdongAges Any age - NCT06654414Recruiting
Smoking cessation support for transgender and gender-diverse adults
This study tests a skills-based program to help transgender and gender-diverse adults quit smoking or vaping. The program focuses on managing stress related to identity and health, and may be more supportive than standard quit programs.
Boston, MassachusettsAges 18 years+ - NCT07865052Recruiting
Psychological support before complex stomach or intestinal surgery
This study tests whether a psychological program before major abdominal surgery can help reduce distress and improve recovery. Participants will receive extra mental health support to prepare for their operation.
Chicago, IllinoisAges 18 years+ - NCT05288140Recruiting
Using daily diaries for people in the intensive care unit
This study checks whether keeping a daily diary for people in the intensive care unit can help after an ICU stay. You may be eligible if you are in the ICU, are sedated and on a breathing machine for at least 24 hours, and can agree to follow-up visits.
BarcelonaAges 18–100 - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75 - NCT06438276Recruiting
Mental health support for teens through school services
This study tests whether psychiatric outreach nurses can help teenagers aged 12-16 who are dealing with mood issues, anxiety, obsessive-compulsive or eating disorder symptoms, or mild self-harm. The goal is to see if this extra support improves their mental health compared to the usual school services.
Kuopio, Northern SavoniaAges 12–16 - NCT07806864Recruiting
Short online program for mental health self-management
This trial offers a short online program that teaches practical skills to help you manage mental health difficulties on your own. It is designed to be quick and easy to use from home.
Regina, SaskatchewanAges 18 years+ - NCT07792837Recruiting
Online intuitive eating program for pregnant women with obesity
This study tests an online program that helps pregnant women with obesity learn to eat intuitively, which means listening to their body's hunger and fullness signals instead of dieting. The goal is to support their well-being during pregnancy.
San Diego, CaliforniaAges 18 years+ - NCT07768670Recruiting
Smartphone exercise program for older adults
This study tests a personalized exercise program delivered through a smartphone app to help older adults become more active. You would use the app to get exercise recommendations and track your progress.
Knoxville, TennesseeAges 65 years+ - NCT06362538Recruiting
Heart health prevention program
This trial tests a program to help prevent heart problems in people who have not had a heart attack or stroke. It is for adults aged 30 and older.
Cotignola, RavennaAges 18–30 - NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+ - NCT07722949Recruiting
A nurse-led program for caregivers of children with autism
This study tests a culturally adapted program where nurses help caregivers build skills to support a child with autism. It aims to reduce stress and improve well-being for both the caregiver and the child.
Faisalābad, Punjab ProvinceAges 18 years+ - NCT07698379Recruiting
Preventing burnout in healthcare workers with compassion therapy
This trial tests whether an online compassion-based therapy program can prevent burnout in Spanish doctors and nurses. It aims to help you manage stress and emotional exhaustion from work.
Zaragoza, SpainAges 18–75
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 441 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.