Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 441 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT07349550Recruiting
Cognitive function, mental health, and work
This trial explores how thinking skills (like memory and focus) relate to common mental health challenges and work life. It aims to find better ways to support people with depression or anxiety who are at risk of needing sick leave.
OsloAges 18–65 - NCT04900064Recruiting
Self-help CBT added to primary care behavioral health
This trial studies whether adding a Swedish self-help version of “CBT” (a structured talking-therapy approach) improves care for adults getting behavioral health support in primary care. It may help people who want support for mental health without needing fully guided therapy sessions.
Varberg, Halland CountyAges 18 years+ - NCT07130734Recruiting
Digital activity program for young adults with depression
This study tests a smartphone app to help people with depressive symptoms become more physically active. If you are between 19 and 40, feel down or low, and are not very active, this program may support you in getting moving.
Auburn, AlabamaAges 19–40 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT06899490Recruiting
Acupuncture study for anxiety with tongue analysis
This trial uses machine learning to analyze tongue color and anxiety scores in people getting acupuncture for anxiety. It aims to see if tongue color can help predict treatment response.
NarbonneAges 18 years+ - NCT06917339Recruiting
A study looking at past treatment records
This trial looks back at medical records in the TrakStar database to understand how treatments were given. It does not test a new drug, but helps researchers learn from past treatment experiences.
Malvern, PennsylvaniaAges 5–120 - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Sunnyvale, CaliforniaAges 18–65 - NCT06295250Recruiting
Help for depression and poverty in Bangladesh
This study tests a program in Bangladesh that helps people with depression and poverty. You and your family would work together to improve your mood and financial situation over 18 months.
Dhaka, Dhaka DivisionAges 18–45 - NCT07799805Recruiting
Doula support for pregnant women in North Central Florida
This study looks at whether having a doula—a trained support person—during pregnancy can help reduce stress and improve health outcomes for mothers. It is designed for women who are eligible for Medicaid and live in North Central Florida.
Gainesville, FloridaAges 15–49 - NCT05961306Recruiting
Testing a stepped screening plan during pregnancy and after birth
This study checks how well a step-by-step screening approach and its tools work for identifying issues during pregnancy (weeks 20–24) or in early postpartum (6–10 weeks after delivery). It may help doctors use more accurate screening to decide who needs further care.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07594743Recruiting
Digital app to prevent depression in new fathers
This study tests a smartphone app designed to help fathers manage stress and mood after their baby is born. Researchers want to see if fathers find the app helpful and easy to use during this major life change.
Providence, Rhode IslandAges 18 years+ - NCT07216638Enrolling by invitation
Better mental health care for kids in primary care
This trial studies how to better integrate mental health care into pediatric primary care clinics across Indiana. It involves surveys, interviews, and looking at patient records to understand and improve care for children.
Indianapolis, IndianaAges 5 years+ - NCT07033052Recruiting
Art therapy for anxiety and depression in teens
This trial tests whether art-based activities can help children and teens aged 8 to 17 who feel anxious or depressed. Parents must agree to let their child join.
Cleveland, OhioAges 8–17 - NCT03364803Recruiting
Sharing treatment results for people with Cushing’s syndrome
This is a study that collects and reviews information about how people with Cushing’s syndrome (including some mild forms and certain “silent” tumors) are diagnosed and treated, and what outcomes they have. It may help researchers understand which treatments work best in different types of the condition.
Basking Ridge, New JerseyAges 14 years+ - NCT02568878RecruitingPhase 3
Creatine to help depression and anxiety in meth users
This trial studies whether creatine can reduce depression and anxiety symptoms in people who currently use methamphetamine and also have depression and anxiety. It may help by improving mood and anxiety scores over the course of the study.
Missoula, MontanaAges 18–59 - NCT06074250RecruitingPhase 2/Phase 3
Pregnancy, mood, and gut health study
This study tests whether a nutritional supplement can help prevent depression and anxiety during and after pregnancy. It looks at how the mother's gut bacteria may influence mood.
Toronto, OntarioAges 18–43 - NCT07871916Recruiting
Mindfulness app for parents going through divorce or separation
This study tests a mindfulness app designed to help parents manage stress during divorce or separation. It may help you feel calmer and more focused as you navigate this challenging time.
Stamford, ConnecticutAges 18 years+ - NCT06766526Recruiting
Online support for emotional adjustment after prostate cancer
This trial tests an online support program to help men cope with emotional distress after prostate cancer. You participate from home using a computer or smartphone.
LinköpingAges 18 years+ - NCT00018057RecruitingPhase 2
Brain study of pediatric anxiety disorders
This study looks at how the brain works in children and adults with anxiety disorders. It uses brain scans (fMRI) and other safe tests to understand anxiety better.
Bethesda, MarylandAges 8–65 - NCT07707037Recruiting
Helping parents cope after a child's cardiac arrest
This study tests if providing clearer information to parents after their child's cardiac arrest can reduce fear and anxiety. It is for parents of children under 17.5 years old who are expected to leave the hospital soon.
Philadelphia, PennsylvaniaAges birth–17 years - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT07272252Recruiting
Nursing support to reduce anxiety after planned C-section
This study tests a special kind of nursing care (narrative nursing) to see if it helps mothers feel less anxious and more confident about breastfeeding after a planned, full-term cesarean section. If you are having a scheduled C-section with a healthy pregnancy and baby, you may be able to join.
Nanchong, SichuanAges 18–50
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 441 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.